Ophthalmic Surg Lasers Imaging 2010 Jan-Feb;41(1):72-7
Department of Ophthalmology, Chang Gung Memorial Hospital, No. 5, Fu-Shin Street, Kweishan, Taoyuan, 333, Taiwan.
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Cochrane Database Syst Rev 2015 Aug 7(8):CD008214. Epub 2015 Aug 7.
Sunderland Eye Infirmary, Queen Alexandra Road, Sunderland, UK, SR2 9HP.
Background: Postoperative vitreous cavity haemorrhage (POVCH) is a significant complication following vitrectomy for proliferative diabetic retinopathy (PDR). It delays visual recovery and can make further treatment difficult if the view of the fundus is significantly obscured. A number of interventions to reduce the incidence of POVCH have been proposed, including the perioperative use of anti-vascular endothelial growth factor (anti-VEGF). Read More
Ophthalmology 2009 Oct 21;116(10):1943-8. Epub 2009 Aug 21.
Ophthalmic Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Objective: To evaluate the effect of preoperative intravitreal bevacizumab (IVB) injection on the rate of early (< or =4 weeks) postvitrectomy hemorrhage in patients with proliferative diabetic retinopathy (PDR).
Design: Prospective, randomized, double-masked clinical trial.
Participants: Sixty-eight eyes of 68 patients undergoing pars plana vitrectomy for management of PDR complications. Read More
Retina 2010 Nov-Dec;30(10):1646-50
Division of Vitreoretinal Surgery, Dhahran Eye Specialist Hospital, Dhahran, Saudi Arabia.
Purpose: The purpose of this study was to evaluate the role of bevacizumab (Avastin), an antivascular endothelial growth factor agent, injected at the end of surgery for preventing postoperative recurrent vitreous hemorrhage in patients undergoing vitrectomy for diabetic eye disease.
Methods: This was a retrospective, comparative, and nonrandomized study on a consecutive series of patients who underwent vitrectomy for diabetic eye disease. Recurrence of postoperative vitreous hemorrhage was compared in patients with and without intravitreal 1. Read More
Middle East Afr J Ophthalmol 2013 Jan-Mar;20(1):51-5
Osaka Rosai Hospital, Clinical Research Center for Occupational Sensory Organ Disability, Kita-Ku, Sakai, Japan.
Purpose: To evaluate the effect of preoperative intravitreal bevacizumab (IVB) on surgical procedures, visual prognosis, and postoperative complications, especially postoperative vitreous hemorrhage, in cases with proliferative diabetic retinopathy (PDR).
Materials And Methods: Seventy-one eyes of 54 consecutive patients (23 eyes of 18 women, 48 eyes of 36 men) were investigated in this study. Twenty-five eyes received IVB one to 30 days before the vitrectomy (Bevacizumab Group) and the other 46 eyes had the vitrectomy alone (Control Group). Read More