A useful radiologic method for preoperative joint-line determination in revision total knee arthroplasty.

Authors:
Jose Romero
Jose Romero
Harvard Medical School
United States
Burkhardt Seifert
Burkhardt Seifert
Biostatistics and Prevention Institute
Switzerland
Oliver Kessler
Oliver Kessler
University of Zurich
Switzerland

Clin Orthop Relat Res 2010 May 5;468(5):1279-83. Epub 2009 Nov 5.

Department of Orthopaedic Surgery, University of Zurich, Balgrist, Switzerland.

Unlabelled: Intraoperative joint-line determination during revision TKA is difficult and no method exists to plan the position preoperatively. Two questions need to be answered: to which extent does the joint line differ from its anatomic position after revision TKA if it has only been determined intraoperatively, and can the joint line be calculated preoperatively based on the transepicondylar width. Of 22 consecutive patients with complete preoperative (before and after primary TKA) and postoperative (after revision TKA) radiograph documentation, the joint-line position was measured on plane radiographs using the medial epicondyle as a reference. On another set of 45 consecutive patients with no knee disorders other than meniscal lesions, the transepicondylar axis width (TEAW) and the perpendicular distance from the medial and lateral epicondyles to the joint line were measured twice by two independent observers on plane AP radiographs of the knee. Significant joint-line alterations were observed after primary and revision TKA, implicating that a method for preoperative planning is needed. Because a linear correlation between the TEAW and the perpendicular distance from the epicondyles to the joint-line tangent was found, the ratio is useful to calculate the true joint-line position from the TEAW before revision TKA.

Level Of Evidence: Level III, therapeutic study. See Guidelines for Authors for a complete description of levels of evidence.

Download full-text PDF

Source
http://dx.doi.org/10.1007/s11999-009-1114-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2853645PMC

Still can't find the full text of the article?

Sign up to send a request to the authors directly.
May 2010
16 Reads

Publication Analysis

Top Keywords

revision tka
16
determination revision
8
teaw perpendicular
8
plane radiographs
8
consecutive patients
8
joint-line position
8
joint-line determination
8
perpendicular distance
8
method preoperative
8
revision
6
joint-line
6
tka
5
epicondyle reference
4
radiographs medial
4
revision tkalevel
4
medial epicondyle
4
reference set
4
teaw revision
4
disorders meniscal
4
true joint-line
4

Similar Publications

Cryptic sequence features in the active postmortem transcriptome.

BMC Genomics 2018 Sep 14;19(1):675. Epub 2018 Sep 14.

City of Hope, Information Sciences - Beckman Research Institute, 4920 Rivergrade Rd., Irwindale, CA, 91706, USA.

Background: Our previous study found that more than 500 transcripts significantly increased in abundance in the zebrafish and mouse several hours to days postmortem relative to live controls. The current literature suggests that most mRNAs are post-transcriptionally regulated in stressful conditions. We rationalized that the postmortem transcripts must contain sequence features (3- to 9- mers) that are unique from those in the rest of the transcriptome and that these features putatively serve as binding sites for proteins and/or non-coding RNAs involved in post-transcriptional regulation. Read More

View Article
September 2018
44 Reads
3.99 Impact Factor

Direct observation of Medicaid beneficiary attempts to fill prescriptions for nicotine replacement medications.

J Am Pharm Assoc (2003) 2018 Jul - Aug;58(4):432-437. Epub 2018 Apr 22.

Objectives: Although many states have expanded Medicaid coverage of cessation medications, utilization remains low. Anecdotal reports suggest that beneficiaries are at times denied coverage of cessation medications at the pharmacy counter. We conducted an observational community-wide case study of Medicaid beneficiary attempts to fill over-the-counter nicotine replacement therapy at pharmacies. Read More

View Article
April 2018
40 Reads

Chemical reaction dynamics.

Chem Soc Rev 2017 Dec;46(24):7481-7482

State Key Laboratory of Molecular Reaction Dynamics, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian 116023, China.

View Article
December 2017
37 Reads
33.38 Impact Factor

Activity of 2-(quinolin-4-yloxy)acetamides in Mycobacterium tuberculosis clinical isolates and identification of their molecular target by whole-genome sequencing.

Int J Antimicrob Agents 2018 Mar 23;51(3):378-384. Epub 2017 Aug 23.

Instituto Nacional de Ciência e Tecnologia em Tuberculose (INCT-TB), Centro de Pesquisas em Biologia Molecular e Funcional, Pontifícia Universidade Católica do Rio Grande do Sul, PUCRS, Av. Ipiranga 6681 - Prédio 92A Tecnopuc, Porto Alegre, RS 90619-900, Brazil; Programa de Pós-Graduação em Biologia Celular e Molecular, PUCRS, Porto Alegre, Brazil.

The 2-(quinolin-4-yloxy)acetamides (QOAs) have been reported to be promising molecules for tuberculosis treatment. Recent studies demonstrated their potent antimycobacterial activity, biological stability and synergism with rifampicin. The identification of the molecular target is an essential step towards the development of a novel drug candidate. Read More

View Article
March 2018
62 Reads
2 PubMed Central Citations(source)
4.30 Impact Factor

Covalent inhibition of protein tyrosine phosphatases.

Mol Biosyst 2017 Jun;13(7):1257-1279

Department of Medicinal Chemistry and Molecular Pharmacology, Department of Chemistry, Center for Cancer Research, and Institute for Drug Discovery, Purdue University, 720 Clinic Drive, West Lafayette, IN 47907, USA.

Protein tyrosine phosphatases (PTPs) are a large family of 107 signaling enzymes that catalyze the hydrolytic removal of phosphate groups from tyrosine residues in a target protein. The phosphorylation status of tyrosine residues on proteins serve as a ubiquitous mechanism for cellular signal transduction. Aberrant function of PTPs can lead to many human diseases, such as diabetes, obesity, cancer, and autoimmune diseases. Read More

View Article
June 2017
57 Reads