Hodgkin's disease--the rare cause of nephrotic syndrome in children.

Ann Acad Med Stetin 2008 ;54(3):10-2; discussion 12

Klinika Pediatrii, Hematologii i Onkologii Dzieciecej Pomorskiej Akademii Medycznej w Szczecinie, Szczecin.

Purpose: Hodgkin's disease (HD) is a potentially curable malignant lymphoma with distinct histology, biologic behavior and clinical characteristics. Renal involvement in HD is rare, but it may be underestimated because renal lesions are not the major manifestation of the disease. The pathogenesis of proteinuria in HD remains unknown.

Case Report: The case of a 17-year-old girl suffering from Hodgkin's disease and nephrotic syndrome has been described.

Conclusion: The authors would like to underline the very rare coincidence of Hodgkin's disease and nephrotic syndrome, the lack of remission after routine prednisone administration and disappearance of nephrotic proteinuria after anticancer therapy.

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December 2009
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