YjhS (NanS) is required for Escherichia coli to grow on 9-O-acetylated N-acetylneuraminic acid.

J Bacteriol 2009 Nov 11;191(22):7134-9. Epub 2009 Sep 11.

Laboratory of Sialobiology, Department of Pathobiology, University of Illinois at Urbana-Champaign, Urbana, Illinois 61802, USA.

The nanATEK-yhcH, yjhATS, and yjhBC operons in Escherichia coli are coregulated by environmental N-acetylneuraminic acid, the most prevalent sialic acid in nature. Here we show that YjhS (NanS) is a probable 9-O-acetyl N-acetylneuraminic acid esterase required for E. coli to grow on this alternative sialic acid, which is commonly found in mammalian host mucosal sites.

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Source
http://dx.doi.org/10.1128/JB.01000-09DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2772488PMC
November 2009
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