J Clin Neuromuscul Dis 2009 Sep;11(1):35-43
Department of Neurology, Tel Aviv Sourasky Medical Center, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.
Sarcoidosis is a multisystem inflammatory disease that can affect the nervous system. Cranial neuropathies are the most frequent presentation of neurosarcoidosis. Involvement of the peripheral nervous system is less common. The presentation is usually subacute or chronic sensorimotor axonal polyneuropathy, whereas acute polyradiculopathy is extremely rare. We report a case of Guillain-Barré-like syndrome probably secondary to sarcoidosis. A review of the literature revealed 9 similar cases. The possibility of a Guillain-Barré-like syndrome as a presenting symptom of sarcoidosis should be considered, especially in patients with atypical features such as cerebrospinal fluid pleocytosis.