Search Our Scientific Publications & Authors

Publications
find publications by category +
Translate page:

Frequency of elevated troponin I and diagnosis of acute myocardial infarction.

Authors:
Usman Javed Waqas Aftab John A Ambrose Ralph J Wessel Mouatou Mouanoutoua Grace Huang Rajat S Barua Michael Weilert Fridolin Sy Deepak Thatai

Am J Cardiol 2009 Jul 4;104(1):9-13. Epub 2009 May 4.

Division of Cardiology, UCSF Fresno Medical Education Program, Fresno, CA, USA.

This study evaluated the incidence and type of acute myocardial infarction (AMI) in a consecutive population with increased troponin I (TnI). AMI has recently been redefined and subclassified. Incidence, demographic data, angiographic findings, and hospital mortality of patients with various AMI subtypes or an increased TnI in the absence of AMI have not been previously reported in a prospective study. Over a 3-month period, all patients admitted from an emergency room or from in-patient services with >1 TnI level >0.04 ng/ml were evaluated and subclassified in AMI subgroups. In-hospital or recent coronary angiograms were reviewed. In-hospital mortality was noted. Of 2,944 patients with serial TnI measurements, 728 had an increased TnI and 701 (23.8%) were evaluated. Two hundred sixteen (30.8% with increased TnI and 42.7% with "rule-out MI" on admission) met criteria for AMI. One hundred forty-three (20.4%) had type 1, 64 (9.1%) had type 2, whereas 461 (65.8%) did not meet criteria for AMI. On multivariate analysis, use of angiography, peak TnI level, hyperlipidemia, and illicit drug use were independently associated with the diagnosis of AMI. TnI of 0.28 ng/ml had a 70% sensitivity and specificity for AMI diagnosis. In conclusion, a minority admitted with increased TnI have AMI by the universal definition. Type 1 is the most common AMI and is associated with higher TnI values and these patients are more likely to undergo angiography. Type 2 AMI is often associated with illicit drug use.

Download full-text PDF

 Source
http://dx.doi.org/10.1016/j.amjcard.2009.03.003DOI Listing
July 2009

Publication Analysis

Top Keywords

increased tni
16
ami
12
tni
10
acute myocardial
8
tni ami
8
criteria ami
8
ami associated
8
myocardial infarction
8
tni level
8
illicit drug
8
type
5
increased
5
subclassified ami
4
level >004
4
patients serial
4
ami universal
4
serial tni
4
diagnosis conclusion
4
tni measurements
4
measurements 728
4

Keyword Occurance

Similar Publications

C-Reactive Protein and High-Sensitive Cardiac Troponins Correlate with Oxidative Stress in Valvular Heart Disease Patients.

Authors:
Muhammad Ishtiaq Jan Riaz Anwar Khan Fozia Ijaz Ahmad Naeem Khan Komal Urooj Azhar Ul Haq Ali Shah Asif Ullah Khan Tahir Ali Ayesha Ishtiaq Muhib Shah Anwar Ullah Iram Murtaza Riaz Ullah Amal Alotaibi H C Ananda Murthy

Oxid Med Cell Longev 2022 30;2022:5029853. Epub 2022 Apr 30.

Department of Applied Chemistry, School of Applied Natural Science, Adama Science and Technology University, P.O. Box, 1888 Adama, Ethiopia.

Background: Valvular heart disease (VHD) is a major contributor to loss of physical function and longevity. Oxidative stress is one of the key causative factors involved in heart disease including VHD. Here, we aimed to illuminate the role and relation of oxidative stress to the VHD risk markers in the human population. Read More

View Article and Full-Text PDF
May 2022
Similar Publications

Early Change in Area Strain Detected by 3D Speckle Tracking Is Associated With Subsequent Cardiotoxicity in Patients Treated With Low Doses of Anthracyclines.

Authors:
Rafael B Piveta Ana Clara T Rodrigues Marcelo L C Vieira Cláudio H Fischer Tania R Afonso Edgar Daminello Felipe M Cruz Tatiana F G Galvão Edgar B L Filho Marcelo Katz Samira S Morhy

Front Cardiovasc Med 2022 21;9:842532. Epub 2022 Mar 21.

Department of Echocardiography, Hospital Israelita Albert Einstein, São Paulo, Brazil.

Objective: To evaluate the prognostic impact of the parameters of myocardial deformation using three-dimensional speckle tracking echocardiography (3DSTE) in patients with breast cancer who underwent chemotherapy with low doses of anthracyclines.

Background: Chemotherapy-related cardiotoxicity has an important prognostic impact on cancer survivors. Three-dimensional STE has revealed more consistent data than two-dimensional techniques and may represent a more accurate tool in the evaluation of myocardial function in patients who underwent chemotherapy. Read More

View Article and Full-Text PDF
March 2022
Similar Publications

Inhibiting thyroid activation in aged human explants prevents mechanical induced detrimental signalling by mitigating metabolic processes.

Authors:
Evelyn Houtman Margo Tuerlings H Eka D Suchiman Nico Lakenberg Frederique M F Cornelis Hailiang Mei Demiën Broekhuis Rob G H H Nelissen Rodrigo Coutinho de Almeida Yolande F M Ramos Rik J Lories Luis J Cruz Ingrid Meulenbelt

Rheumatology (Oxford) 2022 Apr 5. Epub 2022 Apr 5.

Molecular Epidemiology, Department of Biomedical Data Sciences, Leiden University Medical Center, Leiden, The Netherlands.

Objectives: To investigate whether deiodinase inhibitor iopanoic acid (IOP) has chondroprotective properties, a mechanically stress induced model of human aged explants was used to test both repeated dosing and slow-released IOP.

Methods: Human osteochondral explants subjected to injurious mechanical stress (65%MS) were treated with IOP or IOP incapsulated in Poly lactic-co-glycolic acid (PLGA)-polyethylene glycol (PEG) nanoparticles (NP) (PLGA-PEG NPs (NP(IOP)). Changes to cartilage integrity and signalling was determined by Mankin scoring of histology, sulphated glycosaminoglycan (sGAG) release and expression levels of catabolic, anabolic and hypertrophic markers. Read More

View Article and Full-Text PDF
April 2022
Similar Publications

High-efficiency treatment of electroless nickel plating effluent using core-shell [email protected] combined with ozonation: Performance and mechanism.

Authors:
Zhijie Guan Yanping Guo Zhihua Mo Shaojin Chen Jialin Liang Xiaojian Liao Yumin Zhang Zhenhua Huang Weifeng Song Yanbin Xu Xuelian Ou Shuiyu Sun

J Hazard Mater 2022 07 24;433:128768. Epub 2022 Mar 24.

Guangzhou Key Laboratory Environmental Catalysis and Pollution Control, Guangdong Key Laboratory of Environmental Catalysis and Health Risk Control, School of Environmental Science and Engineering, Institute of Environmental Health and Pollution Control, Guangdong University of Technology, Guangzhou 510006, China; Guangdong Province Solid Waste Recycling and Heavy Metal Pollution Control Engineering Technology Research Center, Guangdong Polytechnic of Environmental Protection Engineering, Foshan 528216, China. Electronic address:

Heterogeneous catalytic ozonation (HCO) has been widely applied for the treatment of wastewater. In order to maintain the structural stability and surface catalytic activity of heterogeneous catalysts during the HCO treatment of electroless nickel plating effluent (ENPE), a [email protected] catalyst with a core-shell structure was synthesized. [email protected] was characterized and applied in the removal of total nickel (T) and organic contaminants from actual ENPE, using a coupled system of HCO combined with a magnetic dithiocarbamate chelating resin ([email protected]/O-MDCR). Read More

View Article and Full-Text PDF
July 2022
Similar Publications

Effects of liraglutide vs. lifestyle changes on soluble suppression of tumorigenesis-2 (sST2) and galectin-3 in obese subjects with prediabetes or type 2 diabetes after comparable weight loss.

Authors:
Paola Simeone Romina Tripaldi Annika Michelsen Thor Ueland Rossella Liani Sonia Ciotti Kåre I Birkeland Hanne L Gulseth Augusto Di Castelnuovo Francesco Cipollone Pål Aukrust Agostino Consoli Bente Halvorsen Francesca Santilli

Cardiovasc Diabetol 2022 03 11;21(1):36. Epub 2022 Mar 11.

Department of Medicine and Aging, and Center for Advanced Studies and Technology (CAST), "G. D'Annunzio" University Foundation, Via Luigi Polacchi, 66013, Chieti, Italy.

Background: Soluble suppression of tumorigenesis-2 (sST2) and galectin (Gal)-3 are two biomarkers related to inflammation, metabolic disturbances and to myocardial fibrosis that characterize several cardiac pathological conditions. Increased circulating levels of these molecules have been associated with risk of cardiovascular death. Treatment with liraglutide, a glucagon-like peptide 1 analog, is associated with weight loss, improved glycemic control, and reduced cardiovascular risk. Read More

View Article and Full-Text PDF
March 2022
Similar Publications
}