The use of evidence-based public health (EBPH) approaches is generally recognized as essential to changing public health outcomes. However, using an EBPH decision-making process requires public health practitioners to have the skills to review the evidence and pick the most workable strategy to address the problem at hand for their population of interest and the local context. Although there has been a growing body of academic literature examining the skills needed to translate evidence-based programs in local settings, many public health practitioners have not had the opportunity to learn or develop these skills. This article reports on qualitative interviews conducted to evaluate the process and impact of an EBPH course. The course has been found to assist participants in integrating new and existing skills to make evidence-based decisions. However, participants emphasize that factors external to the course influence their ability to engage in the EBPH process they learned.