Usefulness of routine use of multidetector coronary computed tomography in the "fast track" evaluation of patients with acute chest pain.

Am J Cardiol 2009 Jun 8;103(11):1481-6. Epub 2009 Apr 8.

Heart Institute, Chaim Sheba Medical Center, Tel-Hashomer, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.

Recently published American Heart Association/American College of Cardiology guidelines suggest that multidetector computed tomography (MDCT) may be appropriate for investigating acute chest pain (ACP). Only a few small studies have evaluated the use of MDCT in ACP, where it was not part of routine investigation. We sought to evaluate the routine use of MDCT in a large cohort of patients presenting with ACP in a real-world setting. We studied 785 consecutive patients with ACP who underwent evaluation by MDCT or myocardial perfusion scintigraphy after an observation period of > or = 12 hours. Patients with findings suggestive of significant coronary artery disease (CAD) were referred to coronary angiography. Forty-two patients were hospitalized due to evidence of myocardial ischemia and 44 patients were discharged after the observation period. Of the remaining 699 patients, 340 underwent MDCT and 359 myocardial perfusion scintigraphy. In 22 patients (7%) multidetector computed tomogram showed significant CAD and in 32 (9%) patients myocardial perfusion scintigram showed significant ischemia. Significant CAD was confirmed by coronary angiography in 65% and 60%, respectively. Multidetector computed tomogram was nondiagnostic in 31 patients (9%). Extracardiac findings that might be related to ACP and/or necessitated further investigation were demonstrated by multidetector computed tomogram in 71 patients (21%). During 3-month follow-up, 1 patient (0.3%) with negative multidetector computed tomographic and 9 (3%) with negative myocardial perfusion scintigraphic findings developed an acute coronary syndrome or died. Rehospitalization, due to recurrent chest pain, occurred in 9 patients (3.3%) and 21 patients (7.2%), respectively. In conclusion, MDCT could be an appropriate alternative to traditional noninvasive techniques for investigating ACP.

Download full-text PDF

Source
http://linkinghub.elsevier.com/retrieve/pii/S000291490900536
Publisher Site
http://dx.doi.org/10.1016/j.amjcard.2009.02.009DOI Listing
June 2009

Publication Analysis

Top Keywords

multidetector computed
20
myocardial perfusion
16
patients
13
chest pain
12
computed tomogram
12
acute chest
8
observation period
8
coronary angiography
8
perfusion scintigraphy
8
mdct appropriate
8
computed tomography
8
computed
6
acp
6
mdct
6
multidetector
5
coronary
5
myocardial
5
disease cad
4
tomogram patients
4
patients 21%
4

Altmetric Statistics

Similar Publications