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    Localized hyperkeratosis lenticularis perstans (Flegel's disease).

    Cutis 1991 Sep;48(3):201-4
    Department of Dermatology, Fundación Jiménez Díaz, Universidad Autónoma, Madrid, Spain.
    A case of hyperkeratosis lenticularis perstans involving only the back of a thirty-nine-year-old woman is reported. Histologic examination showed foci of compact and eosinophilic hyperkeratosis overlying a thinned stratum malpighii. In the underlying papillary dermis there was no evidence of inflammatory infiltrate. This case demonstrates that hyperkeratosis lenticularis perstans may appear as a localized disorder, and that the inflammation is not an essential pathogenic process in this disorder.

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