F-18 FDG PET-CT imaging in recurrent cerebral gliosarcoma.

Clin Nucl Med 2009 Mar;34(3):153-4

Department of Radiology, Division of Nuclear Medicine, PET Imaging Science Center, Keck School of Medicine, University of Southern California, Los Angeles, California 90033, USA.

We report the F-18 FDG PET-CT appearance of recurrent gliosarcoma (GS) with extracranial extension in a 47-year-old man who underwent surgical resection of a right frontal GS 5 months earlier. F-18 FDG PET demonstrated moderate uptake in the recurrent disease. GS is a very rare, biphasic primary neoplasm of the central nervous system, composed of glioblastoma multiforme mixed with a sarcomatous component. It occurs in adults of middle age and carries a poor prognosis. The median survival reported is less than a year. The results suggest that F-18 FDG PET imaging may be useful in detecting recurrent GS.

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http://dx.doi.org/10.1097/RLU.0b013e3181966fc6DOI Listing
March 2009
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