Int J Pediatr Otorhinolaryngol 2009 Jun 25;73(6):833-7. Epub 2009 Mar 25.
Department of Oral and Maxillofacil Surgery, China.
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Int J Oral Maxillofac Surg 2011 Jun 1;40(6):572-6. Epub 2011 Mar 1.
Department of Oral and Maxillofacial Surgery, The Second Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.
Picibanil (OK-432) and bleomycin have been used as alternative sclerosing agents for lymphatic malformations. This study evaluated the clinical curative effect of sclerotherapy using fibrin glue combined with OK-432 and bleomycin for the treatment of macrocystic lymphatic malformations of the face and neck. Fifteen paediatric patients (6 males; 9 females, aged 13 months to 14 years) who had received percutaneous sclerotherapy for massive macrocystic lymphatic malformations of the face and neck were retrospectively reviewed. Read More
Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2007 Sep 11;104(3):338-44. Epub 2007 Apr 11.
Department of Oral and Maxillofacial Surgery, School and Hospital of Stomatology, Wuhan University, Wuhan, People's Republic of China.
Objective: The objective of this study was to determine prognostic factors and complication rates related to the surgical management of lymphatic malformations of oral and cervicofacial regions in children.
Study Design: The charts of 117 children operated on for oral and cervicofacial lymphatic malformations were retrospectively reviewed. Treatment outcomes were analyzed for correlation with several factors, including age at presentation, sex, associated symptoms, anatomical site of involvement, extent of disease, operative complications, histological pattern, and recurrence. Read More
Int J Pediatr Otorhinolaryngol 2011 May 21;75(5):673-7. Epub 2011 Mar 21.
Department of Paediatric Otolaryngology, Great Ormond Street Hospital, Great Ormond Street, London, WC1N 3JH, United Kingdom.
Objective: There has been much recent focus on sclerotherapy treatment of lymphatic malformations with OK432. Surgical treatment however can have a number of advantages, including complete curative excision. The aim of this study was to evaluate the results of surgical excision as the primary (first) treatment for this condition. Read More
J Craniofac Surg 2013 Jul;24(4):1307-9
Department of Maxillofacial Surgery and ENT, Avicenne University Medical Center, Rabat, Morocco.
Purpose: Lymphatic malformations (LMs) are benign lesions. Most of them are found in head and neck regions as asymptomatic mass, but giant lymphangiomas may affect breathing or swallowing and constitute a major therapeutic challenge.
Methods: A retrospective analysis of giant head and neck LMs with impairment of respiration or swallow for the past 11 years was performed in the Department of Maxillofacial Surgery and ENT of the Avicenne Medical University Center. Read More