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Cyclic pamidronate treatment in Bruck syndrome: proposal of a new modality of treatment.

Pediatr Int 2008 Dec;50(6):836-8

Division of Endocrinology, Department of Pediatrics, Faculty of Medicine, Hacettepe University, Ankara, Turkey.

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December 2008
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ICD therapy in the elderly: a retrospective single-center analysis of mortality.

Herzschrittmacherther Elektrophysiol 2021 Jan 29. Epub 2021 Jan 29.

Department of Electrophysiology, Cologne, University Heart Center Cologne, Kerpener Str. 62, 50937, Köln, Germany.

Background: Current implantable cardioverter-defibrillator (ICD) guidelines do not impose age limitations for ICD implantation (IMPL) and generator exchange (GE); however, patients (pts) should be expected to survive for 1 year. With higher age, comorbidity and mortality due to non-sudden cardiac death increase. Thus, the benefit of ICD therapy in elderly pts remains unclear. Read More

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January 2021

Non invasive in vivo monitoring of dimethyl fumarate treatment in EAE by assessing the glucose metabolism in secondary lymphoid organs.

Eur J Immunol 2020 Dec 28. Epub 2020 Dec 28.

Department of Dermatology, Venerology and Allergology, Charité Universitätsmedizin Berlin, Charitéplatz1, Berlin, Germany.

[ F]FDG-PET/CT is a high sensitive functional diagnostic imaging modality to monitor tumor but also immune cell activation by determination of the glucose metabolism. Our results show that the anti-inflammatory effects of immunotherapeutics like DMF can be assessed non invasively in vivo during Th1/Th17 cell-mediated encephalomyelitis (EAE) by [ F]FDG-PET/CT imaging of the draining lymph nodes. Read More

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December 2020

Optical coherence tomography-based assessment of retinal vascular pathology in cerebral small vessel disease.

Neurol Res Pract 2020 15;2:13. Epub 2020 May 15.

Department of Neurology, University Hospital of Ulm, Ulm, Germany.

Background: Cerebral small vessel disease (CSVD) is a disorder of brain vasculature that causes various structural changes in the brain parenchyma, and is associated with various clinical symptoms such as cognitive impairment and gait disorders. Structural changes of brain arterioles cannot be visualized with routine imaging techniques in vivo. However, optical coherence tomography (OCT) is thought to be a "window to the brain". Read More

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Nudging children toward healthier food choices: An experiment combining school and home gardens.

Glob Food Sec 2020 Sep;26:100454

Leibniz Institute of Vegetable and Ornamental Crops (IGZ), Großbeeren, Germany.

School gardens have become a widely used approach to influence children's food knowledge, preferences and choices in low- and high-income countries alike. However, evidence indicates that such programs are more effective at influencing food knowledge and preferences than actual food choices. Such finding may occur because school gardens insufficiently influence the food behavior of parents and because healthy food items are not always available in children's homes. Read More

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September 2020

Non-responsive celiac disease may coincide with additional food intolerance/malabsorption, including histamine intolerance.

Med Hypotheses 2021 Jan 21;146:110404. Epub 2020 Nov 21.

Clinical Institute of Medical and Chemical Laboratory Diagnosis, Medical University of Graz, Auenbruggerplatz 30, A-8036 Graz, Austria.

Background And Pilot Study: Celiac disease (CD) or gluten malabsorption is a well-defined autoimmune disorder characterized by mucosal gastrointestinal reaction to ingested gluten proteins. The necessary treatment for CD is a gluten-free diet. However, up to 30% of celiac patients experience persistent or recurring abdominal complaints despite following an exact gluten-free diet. Read More

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January 2021