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Before the call.

Authors:
Robert Resta

J Genet Couns 2009 Feb 21;18(1):12. Epub 2008 Oct 21.

Hereditary Cancer Clinic, Swedish Medical Center, 1221 Madison, #1220, Seattle, WA 98104, USA.

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http://dx.doi.org/10.1007/s10897-008-9193-9DOI Listing
February 2009

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A mobile app to transparently distinguish single- from dual-task walking for the ecological monitoring of age-related changes in daily-life gait.

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Francesca Lunardini Milad Malavolti Alessandra Laura Giulia Pedrocchi N Alberto Borghese Simona Ferrante

Gait Posture 2021 Feb 25;86:27-32. Epub 2021 Feb 25.

NearLab, Department of Electronics, Information and Bioengineering, Politecnico di Milano, Via Ponzio 34/5, 20133, Milano, MI, Italy.

Background: Early detection of gait impairments in older adults allows the early uncovering of fall risk and/or cognitive deficits, resulting in timely interventions. Dual-task paradigms have been shown to be more sensitive than single-task conditions for the detection of subtle yet relevant gait impairments.

Research Question: Can a system - encompassing a pair of instrumented insoles and a customized mobile app - transparently and accurately study ecological walking activities in single- and dual-task conditions, with the aim of detecting early and subtle age-related alterations of gait?

Methods: The system was tested on 19 older adults during outdoor walking (two identical single-task trials and two motor-cognitive dual-task trials with the user engaged in a simple phone call and in a cognitive-demanding phone call). Read More

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Federica Guerrini Lorenzo Mari Renato Casagrandi

Sci Total Environ 2021 Feb 20;777:145944. Epub 2021 Feb 20.

Dipartimento di Elettronica, Informazione e Bioingegneria, Politecnico di Milano Via Ponzio 34/5, 20133 Milano, Italy. Electronic address:

Plastic pollution is widespread in the global oceans, but at the same time several other types of hydrophobic pollutants contaminate the marine environment. As more and more evidence highlights, microplastics and polluting chemicals are intertwined via adsorption/desorption processes. A thorough assessment of their total impact on marine ecosystems thus requires that these two kinds of pollution are not considered separately. Read More

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Hydrocarbon pollution in Atlantic coast of Mauritania (Levrier Bay Zone): Call for sustainable management.

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Cherif Ahmed Ahmed Elmamy Bah Mohamed Lemine Abdellahi Hassan Er-Raioui Aly Dartige Mohamed Lemine Zamel Pr Mohamed Vadel Deida

Mar Pollut Bull 2021 Mar 3;166:112040. Epub 2021 Mar 3.

Unit of Molecular Chemistry and Environment, Faculty of Sciences and Techniques, University of Nouakchott Al-Aasriya, King Faiçal Avenue, Nouakchott, Mauritania.

Levrier Bay is an important fishing area which is under growing anthropogenic pressures seriously threatening this treasure. Among these pressures Polycyclic Aromatic Hydrocarbon are of great environmental concern. Therefore, 16 EPA-PAHs were analyzed using GC-MS in Perna perna species and sediment. Read More

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Multiple roles of ABC transporters in yeast.

Authors:
Sonam Kumari Mohit Kumar Naseem A Gaur Rajendra Prasad

Fungal Genet Biol 2021 Mar 3:103550. Epub 2021 Mar 3.

Amity Institute of Integrative Science and Health and Amity Institute of Biotechnology, Amity University Gurgaon, Haryana, India. Electronic address:

The ATP binding cassette (ABC) transporters, first discovered as high-affinity nutrient importers in bacteria, rose to prominence when their ability to confer multidrug resistance (MDR) to cancer cells was realized. The most characterized human permeability glycoprotein (P-gp) is a dominant exporter of anti-cancer drugs and its overexpression is directly linked to MDR. The overexpression of drug efflux pumps belonging to the ABC superfamily is also a frequent cause of resistance to antifungals. Read More

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The FDA and PLATO Investigators death lists: Call for a match.

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Victor L Serebruany Jean-Francois Tanguay Thomas A Marciniak

Int J Clin Pract 2021 Mar 6:e14105. Epub 2021 Mar 6.

Bethany Beach, DE, USA.

Purpose: The FDA-issued PLATO trial dataset revealed that some primary death causes (PDCs) were inaccurately reported favouring ticagrelor. However, the PLATO Investigators operated the shorter death list of uncertain quality. We compared if PDC match when trial fatalities were reported to the FDA and by the PLATO Investigators. Read More

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