Narrowband UVB (311 nm, TL01) phototherapy for pityriasis lichenoides.

Authors:
Kenan Aydogan
Kenan Aydogan
Uludag University
Turkey
Hayriye Saricaoglu
Hayriye Saricaoglu
Uludag University Medical Faculty
Turkey
Hakan Turan
Hakan Turan
Duzce University Medical Faculty
Turkey

Photodermatol Photoimmunol Photomed 2008 Jun;24(3):128-33

Department of Dermatology, Faculty of Medicine, Uludag University, Bursa, Turkey.

Background/purpose: Narrowband (NB) UVB (NB-UVB) phototherapy has recently demonstrated high levels of efficacy and tolerability in a variety of skin diseases. The purpose of the present study was to assess the efficacy of NB-UVB phototherapy in the management of pityriasis lichenoides (PL).

Methods: The therapeutic response in 31 PL patients (23 pityriasis lichenoides et varioliformis acuta; PLEVA, eight pityriasis lichenoides chronica; PLC) treated with NB-UVB phototherapy between 2000 and 2007 was assessed.

Results: NB-UVB treatment led to a complete response (CR) in 15 out of 23 PLEVA patients (65.2%) with a mean cumulative dose of 23 J/cm(2) after a mean number of 43.4 exposures and a partial response (PR) in eight patients (34.8%) with a cumulative dose of 15.6 J/cm(2) after a mean number of 32.3 exposures. NB-UVB treatment led to CR in seven out of eight PLC patients (87.5%) with a mean cumulative dose of 18.4 J/cm(2) after a mean number of 45.8 exposures and PR in one patient (12.5%) with a cumulative dose of 9.1 J/cm(2) after a mean number of 19 exposures. Relapses occurred in four PL patients within a mean time period of 6 months.

Conclusion: NB-UVB therapy is an effective, safe and practical alternative treatment modality for the management of PLEVA and PLC.

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Source
http://doi.wiley.com/10.1111/j.1600-0781.2008.00350.x
Publisher Site
http://dx.doi.org/10.1111/j.1600-0781.2008.00350.xDOI Listing
June 2008
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