Regression of symptoms after selective iron chelation therapy in a case of neurodegeneration with brain iron accumulation.

Mov Disord 2008 Apr;23(6):904-7

Centro della Microcitemia e Anemie Congenite, Ospedale Galliera, Genoa, Italy.

We report the results of iron chelating treatment with deferiprone in a 61-year-old woman with signs and symptoms of neurodegeneration with brain iron accumulation (NBIA). After 6 months of therapy the patient's gait had improved and a reduction in the incidence of choreic dyskinesias was observed. Her gait returned to normal after an additional 2 months of therapy, at which time there was a further reduction in involuntary movements and a partial resolution of the blepharospasm.

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http://dx.doi.org/10.1002/mds.22002DOI Listing
April 2008
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