Clin Cancer Res 2008 Mar;14(6):1788-96
Department of Internal Medicine, Washington University School of Medicine, St. Louis, Missouri, USA.
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Expert Rev Hematol 2018 Oct;11(10):761-771
a Division of Hematology , Mayo Clinic , Rochester , MN , USA.
Introduction: Proteasome inhibitors (PIs) have been an integral part of treatment for multiple myeloma (MM) over the past decade. Many newer PIs are being evaluated in pre-clinical and clinical setting, with an aim to improve the safety, efficacy and resistance profile of this class of drugs. Ixazomib is the first oral PI with a robust efficacy and favorable safety profile in MM. Read More
J Med Virol 2018 May 1;90(5):907-918. Epub 2018 Feb 1.
Evidence Based Medicine Research Group & Faculty of Applied Sciences, Ton Duc Thang University, Ho Chi Minh City, Vietnam.
Daclatasvir, asunaprevir (ASV), and beclabuvir (BCV) are direct-acting antivirals (DAAs) for patients with hepatitis C virus genotype 1 infection. This systematic review and meta-analysis investigating the efficacy and safety of this three-drug combination in HCV genotype 1 infection. Eleven electronic search engines were searched for relevant publications. Read More
Tumour Biol 2015 Aug 5;36(8):5727-42. Epub 2015 Jul 5.
Department of Immunology, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran.
The selective and efficient drug delivery to tumor cells can remarkably improve different cancer therapeutic approaches. There are several nanoparticles (NPs) which can act as a potent drug carrier for cancer therapy. However, the specific drug delivery to cancer cells is an important issue which should be considered before designing new NPs for in vivo application. Read More
Tunis Med 2013 Jul;91(7):471
J Reprod Med 2008 Sep;53(9):711-3
Department of Obstetrics and Gynecology, Alexandra General Hospital, Athens, Greece.
Background: Actinomycosis is a chronic infection caused by Actinomyces israeli, a gram-positive saprophytic anaerob, a normal inhabitant of the upper intestinal tract.
Case: We report a case of a 35-year-old female with an intrauterine device (IUD) who appeared in the emergency department with clinical characteristics of appendicitis. Ultrasound and computed tomography were performed, revealing an ovarian tumor formation and acute appendicitis. Read More