The changing pattern of kidney cancer incidence and mortality in Europe.

BJU Int 2008 Apr 30;101(8):949-58. Epub 2008 Jan 30.

Unité d'épidemiologie du cancer et Registres des tumeurs de Vaud et Neuchâtel, Institut de médecine sociale et préventive, Centre Hospitalier Universitaire Vaudois et Université de Lausanne, Lausanne, Switzerland.

Objective: To update trends in kidney cancer mortality in 32 European countries and the European Union (EU) as a whole, as mortality from kidney cancer has increased throughout Europe until the late 1980s or early 1990s, and has tended to stabilise or decline thereafter.

Methods: Data from the World Health Organization mortality database over the period 1980-2004 were used to compute age-specific and age-standardized (world standard) rates per 100,000 persons at all ages, and truncated to 35-64 years.

Results: In men in the EU, mortality rates from kidney cancer peaked at 4.8 per 100,000 in 1990-1994, and declined to 4.1 (-13%) in 2000-2004. In women in the EU, the corresponding values were 2.1 in 1990-1994 and 1.8 (-17%) in 2000-2004. The main decreases were in Scandinavian countries, and other western European countries. In most eastern European countries kidney mortality rates tended to stabilise, even if values remained high, especially in the Czech Republic and Baltic countries. For kidney cancer incidence, there were decreases in rates for both sexes in Sweden throughout the 25-year calendar period considered. In the last 10 years considered, incidence rates decreased or tended to stabilise also in other northern European countries in both sexes, except in the UK.

Conclusion: The present work confirms and further quantifies the recent favourable trends in kidney cancer mortality and (to a lesser degree) in incidence across most European countries. Thus, improvements in diagnosis and treatments cannot largely explain the declines in mortality. Apart from a favourable role of reduced tobacco smoking in men, the interpretation of these trends remains undefined.

Download full-text PDF

Source
http://doi.wiley.com/10.1111/j.1464-410X.2008.07451.x
Publisher Site
http://dx.doi.org/10.1111/j.1464-410X.2008.07451.xDOI Listing
April 2008
6 Reads

Publication Analysis

Top Keywords

kidney cancer
24
european countries
20
tended stabilise
12
mortality
8
trends kidney
8
cancer mortality
8
cancer incidence
8
countries kidney
8
mortality rates
8
countries
7
kidney
7
cancer
6
european
6
rates
5
remained high
4
stabilise values
4
eastern european
4
high czech
4
kidney mortality
4
rates tended
4

References

(Supplied by CrossRef)
Price and cigarette consumption in Europe
Gallus et al.
Tob Control 2006

World Health Organization. et al.
1967

World Health Organization. et al.
1977

World Health Organization. et al.
1992

Doll et al.
1982

Parkin et al.
2005

Engholm et al.
2007

Similar Publications