Primitive neuroectodermal tumor of the lung with pericardial extension: a case report.

Cardiovasc Pathol 2007 Nov-Dec;16(6):351-3. Epub 2007 Apr 2.

Department of Internal Medicine, International Islamic University Malaysia, Jalan Hospital Campus, Kuantan, Pahang Darul Makmur 25150, Malaysia.

A 16-year-old student presented with a 4-week history of progressive shortness of breath, loss of appetite, and occasional blood-tinged sputum. The chest X-ray revealed massive right-sided pleural effusion with cardiomegaly. An echocardiogram revealed a large pericardial mass with massive pericardial effusion. Subsequent computed tomography of the thorax revealed a large heterogeneous mass in the right lung with extension into the pericardium. Lung biopsy revealed primitive neuroectodermal tumor (PNET) with small round blue cells, Homer-Wright rosettes, and CD99 positivity. We discuss pericardial metastases of PNET and its implication in this patient.

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http://dx.doi.org/10.1016/j.carpath.2007.02.002DOI Listing
January 2008
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