Enteropathogen Resource Integration Center (ERIC): bioinformatics support for research on biodefense-relevant enterobacteria.

Nucleic Acids Res 2008 Jan 13;36(Database issue):D519-23. Epub 2007 Nov 13.

Genome Center, University of Wisconsin, 425G Henry Mall, Madison, Madison, WI 53703, USA.

ERIC, the Enteropathogen Resource Integration Center (www.ericbrc.org), is a new web portal serving as a rich source of information about enterobacteria on the NIAID established list of Select Agents related to biodefense-diarrheagenic Escherichia coli, Shigella spp., Salmonella spp., Yersinia enterocolitica and Yersinia pestis. More than 30 genomes have been completely sequenced, many more exist in draft form and additional projects are underway. These organisms are increasingly the focus of studies using high-throughput experimental technologies and computational approaches. This wealth of data provides unprecedented opportunities for understanding the workings of basic biological systems and discovery of novel targets for development of vaccines, diagnostics and therapeutics. ERIC brings information together from disparate sources and supports data comparison across different organisms, analysis of varying data types and visualization of analyses in human and computer-readable formats.

Download full-text PDF

Source
http://dx.doi.org/10.1093/nar/gkm973DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2238966PMC
January 2008
19 Reads

Publication Analysis

Top Keywords

resource integration
8
integration center
8
enteropathogen resource
8
experimental technologies
4
technologies computational
4
high-throughput experimental
4
studies high-throughput
4
focus studies
4
computational approaches
4
data unprecedented
4
opportunities understanding
4
understanding workings
4
unprecedented opportunities
4
increasingly focus
4
wealth data
4
approaches wealth
4
underway organisms
4
genomes completely
4
completely sequenced
4
pestis genomes
4

References

(Supplied by CrossRef)

Peters et al.
PLoS biology 2005

Glasner et al.
Nucleic Acids Research 2006

Brinkley et al.
Infection and Immunity 2006

Finn et al.
Nucleic Acids Research 2006

Nucleic Acids Research 2007

Siguier et al.
Nucleic Acids Research 2006

Molecular & Cellular Proteomics 2006

Darling et al.
Genome Research 2004

Stein et al.
Genome Research 2002

Gene Ontology Consortium et al.
Nucleic Acids Research 2004

Ashburner et al.
Nature genetics 2000

Similar Publications