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[Esophageal cancer in patient with chagasic megaesophagus].

Authors:
Maria Aparecida Coelho de Arruda Henry Mauro Masson Lerco Walmar Kerche de Oliveira

Arq Gastroenterol 2007 Apr-Jun;44(2):151-5

Departamento de Cirurgia e Ortopedia, Faculdade de Medicina de Botucatu, Universidade Estadual Paulista, Botucatu, SP.

Background: Megaesophagus constitutes a public health problem in our country since it affects individuals in the most productive phase of their lives. During the development of the disease, people suffering from it may present association with esophageal cancer.

Aim: To analyze the clinical and epidemiological aspects of patients with megaesophagus and esophageal cancer.

Methods: Twenty patients with megaesophagus and cancer (group 1) and 20 patients with esophageal cancer (group 2) were retrospectively analyzed. Demographic data, habits (alcoholism and smoking), tumor histological type, lesion location, cellular differentiation, staging, treatment and survival were assessed.

Results: No difference was observed between the groups in relation to age, sex, lesion location, tumor histological type, cellular differentiation, staging or survival. As regards habits, the association of alcoholism with smoking was observed in a larger number of patients with esophageal cancer without the megaesophagus antecedent.

Conclusion: The clinical characteristics of patients with megaesophagus and cancer do not differ from those of patients with malignant esophageal neoplasia, particularly as regards the unfavorable prognosis with the instituted treatment. Patients with megaesophagus may present esophageal tumor at any part of the organ.

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http://dx.doi.org/10.1590/s0004-28032007000200013DOI Listing
June 2008

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