[Dermatofibrosarcoma protuberans: surgical treatment using the Tübingen technique (31 cases)].

Ann Dermatol Venereol 2007 Jan;134(1):31-4

Clinique de Dermatologie, Université du Piémont Oriental, Novara, Italie.

Background: Dermatofibrosarcoma protuberans is a rare cutaneous sarcoma that progresses slowly. Although it exhibits pronounced local aggressiveness, it rarely metastasises. The condition is difficult to treat on account of asymmetric and unpredictable growth as well as the frequency of relapse. Treatment is primarily surgical.

Patients And Methods: We report 31 cases of dermatofibrosarcoma protuberans operated at the Dermatology Clinic of Novara between 1997 and 2004 using the Tübingen technique. An immunohistochimical study was performed and screening was carried out for possible extension of the neoplasm into muscle.

Results: Muscular involvement was seen in 4 cases. No relapses were seen over a median survival period of 3 years and no patients were lost to follow-up.

Discussion: The Mohs technique is the surgical method of reference and allows tumour eradication with sparing of healthy tissue. The Tübingen method constitutes an alternative approach requiring fewer histological sections. The results obtained in our series were good and no relapses were seen over a median survival period of 3 years.

Download full-text PDF

Source

Still can't find the full text of the article?

We can help you send a request to the authors directly.
January 2007
4 Reads

Publication Analysis

Top Keywords

dermatofibrosarcoma protuberans
8
tübingen technique
8
median survival
8
relapses median
8
survival period
8
period years
8
cases dermatofibrosarcoma
4
eradication sparing
4
report cases
4
protuberans operated
4
methods report
4
dermatology clinic
4
clinic novara
4
allows tumour
4
operated dermatology
4
tumour eradication
4
relapse treatment
4
growth well
4
tissue tübingen
4
unpredictable growth
4

Similar Publications