J Emerg Med 2007 Jan;32(1):119-21
Department of Radiology, Faculty of Medicine, Dokuz Eylul University, Izmir, Turkey.
Abdom Radiol (NY) 2022 Jul 22. Epub 2022 Jul 22.
Radiology and Imaging Sciences, Clinical Center (CC), National Institutes of Health, 10 Center Drive, Bethesda, MD, 20892-1109, USA.
Purpose: Upfront knowledge of tumor growth rates of clear cell renal cell carcinoma in von Hippel-Lindau syndrome (VHL) patients can allow for a more personalized approach to either surveillance imaging frequency or surgical planning. In this study, we implement a machine learning algorithm utilizing radiomic features of renal tumors identified on baseline magnetic resonance imaging (MRI) in VHL patients to predict the volumetric growth rate category of these tumors.Materials And Methods: A total of 73 VHL patients with 173 pathologically confirmed Clear Cell Renal Cell Carcinoma (ccRCCs) underwent MRI at least at two different time points between 2015 and 2021. Read More
J Investig Med High Impact Case Rep 2022 Jan-Dec;10:23247096221111775
Division of Neonatology, Department of Pediatrics, Los Angeles County Hospital Medical Center, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.
A male infant born at 34 weeks' gestation presented with acute cardiorespiratory decompensation soon after birth followed by renal failure. Initial clinical course was complicated by ventilator requirement, bilateral pneumothoraces, and hypotension managed with multiple inotropes. Persistent renal failure with oliguria and renal ultrasound showing noncystic medical renal disease prompted further investigation. Read More
Abdom Radiol (NY) 2022 Jul 1. Epub 2022 Jul 1.
Division of Abdominal Imaging, Department of Radiology, Massachusetts General Hospital, 55 Fruit Street, White Building, Room 270, Boston, MA, 02114, USA.
Purpose: Prior case reports have noted an increase in renal size and perinephric stranding accompanying immunotherapy-related renal toxicity due to checkpoint-inhibitor therapy. The purpose of this investigation was to systematically evaluate if immunotherapy-related renal toxicity affects renal size and possible associated imaging findings.Methods: This retrospective multi-hospital study included 25 patients (13 men), mean age 67 years (range 46-83) who received immune-checkpoint inhibitors for cancer treatment, developed biopsy-proven immunotherapy-related nephritis, and who also had abdominal imaging before, during, and after nephritis was diagnosed. Read More
AJR Am J Roentgenol 2022 Jun 29. Epub 2022 Jun 29.
Department of Medical Imaging, The Ottawa Hospital, 1053 Carling Avenue, Room C159, Ottawa, ON.
The MRI clear-cell likelihood score predicts the likelihood that a renal mass is clear-cell renal cell carcinoma (ccRCC). A CT-based algorithm has not yet been established. To develop and evaluate a CT-based algorithm for diagnosing ccRCC among small (≤4 cm) solid renal masses. Read More
Pflugers Arch 2022 08 24;474(8):783-797. Epub 2022 Jun 24.
Institute of Physiology and National Centre of Competence in Research "Kidney.CH", University of Zürich, CH-8057, Zurich, Switzerland.
Renal erythropoietin (Epo)-producing (REP) cells represent a rare and incompletely understood cell type. REP cells are fibroblast-like cells located in close proximity to blood vessels and tubules of the corticomedullary border region. Epo mRNA in REP cells is produced in a pronounced "on-off" mode, showing transient transcriptional bursts upon exposure to hypoxia. Read More