Alpha(2)-blocker helps to avoid systemic to pulmonary shunt in a prostaglandin dependent infant with critical pulmonary valve stenosis.

J Coll Physicians Surg Pak 2006 Dec;16(12):780-2

Department of Cardiovascular Diseases, Section of Pediatric Cardiology, King Faisal Specialist Hospital and RC, Jeddah, Saudi Arabia.

A 27 days old newborn with critical pulmonary valve stenosis remained prostaglandin (PGE(1)) dependent for 2 weeks after successful balloon valvuloplasty. Only the introduction of Phentolamine in his medication regimen, allowed PGE(1) to be weaned off within days of this therapy. The medication was continued for 4 days and replaced by angiotensin converting enzyme inhibitor (Captopril). Few weeks after the discharge, the patient remained clinically stable with acceptable saturation.

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http://dx.doi.org/12.2005/JCPSP.780782DOI Listing
December 2006
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