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    Treatment of angiokeratoma of Fordyce with pulsed dye laser.
    Dermatol Surg 2006 Sep;32(9):1147-50
    Department of Dermatology, Tel Aviv University, Tel Aviv, Israel.
    Background: Angiokeratomas of Fordyce are typically asymptomatic vascular lesions characterized by blue-to-red papules with a scale surface, most often located on the scrotum. Although considered benign, the lesions may bleed, either spontaneously or secondary to rupture, leading to patient anxiety and social embarrassment.

    Objective: The objective was to determine the safety and effectiveness of 585-nm pulsed dye laser for the treatment of angiokeratomas of Fordyce.

    Methods: Twelve patients with Fitzpatrick skin type II to IV were treated for angiokeratomas of Fordyce with pulsed dye laser (5.5-8.0 J/cm(2)) in two to six sessions. Lesion clearance was evaluated by two specialists on the basis of digital photographs taken before the first treatment and 2 months after the last treatment.

    Results: Seven patients had an excellent response (clearance rating 75%-100%) and five patients had a good response (clearance rating 50%-75%). Transient purpura and pain were present in all patients. Bleeding during treatment occurred in five patients. There were no permanent side effects.

    Conclusion: Pulsed dye laser is effective and safe for the treatment of angiokeratoma of Fordyce, with minimum side effects, providing an additional nonablative therapeutic option.

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    Treatment of angiokeratoma of Fordyce with long-pulse neodymium-doped yttrium aluminium garnet laser.
    Dermatol Surg 2009 Jan 8;35(1):92-7. Epub 2008 Dec 8.
    Department of Dermatology, Meram Medical Faculty, Selçuk University, Konya, Turkey.
    Background: Angiokeratomas are typically asymptomatic, blue-to-red papules with a scaly surface located on the scrotum, shaft of penis, labia majora, inner thigh, or lower abdomen. The treatment of angiokeratomas may be necessary if they bleed and lead to patient anxiety.

    Objective: To determine the safety and effectiveness of long-pulse 1,064 neodymium-doped yttrium aluminium garnet (Nd:YAG) laser for the treatment of angiokeratomas of Fordyce. Read More
    Pulsed dye laser versus long pulsed Nd:YAG laser in the treatment of angiokeratoma of Fordyce: A randomized, comparative, observer-blinded study.
    J Dermatolog Treat 2016 7;27(3):270-4. Epub 2015 Oct 7.
    a Department of Dermatology , Faculty of Medicine, Al-Azhar University Hospital , Cairo , Egypt.
    Background: Angiokeratoma of Fordyce is typically asymptomatic, blue-to-red papules with a scaly surface located on the scrotum, shaft of penis or labia majora. They can be treated with some locally destructive treatment modalities such as excision, electrocoagulation, cryotherapy and laser.

    Objectives: To compare the effects of the pulsed dye laser versus long pulsed Nd:YAG laser in the treatment of angiokeratoma of Fordyce. Read More
    [Multiple Fordyce-type angiokeratomas of the scrotum. An iatrogenic case].
    Pathologica 1998 Feb;90(1):46-50
    Servizio di Anatomia Patologica, IRCCS-Ospedale, Casa Sollievo della Sofferenza, San Giovanni Rotondo (FG).
    Background: Angiokeratoma is a wart-like vascular lesion of the skin. There are five types of angiokeratoma: the Mibelli-type, the Fordyce-type, the solitary and multiple (papular) types, the angiokeratoma circumscriptum, and the angiokeratoma corporis diffusum. The "Mibelli-type" occurs on the acral sites, mainly digits, of young people affected by repeated attacks of chilblain, which result in a deleterious effects on vessel walls. Read More
    Report of two angiokeratoma of Fordyce cases treated with a 1064 nm long-pulsed Nd:YAG laser.
    Photodermatol Photoimmunol Photomed 2009 Jun;25(3):166-8
    Civaş Clinic, Ankara, Turkey.
    Various laser treatment modalities for angiokeratomas have been reported in the literature. A 60-year-old male patient presented for the treatment of multiple angiokeratomas of the scrotum and a 56-year-old female patient presented for the treatment of vulvar angiokeratomas. A 1064 nm long-pulsed Nd:YAG laser was used to treat the patients' lesions. Read More