Am J Clin Pathol 2006 Jun;125 Suppl:S95-123
Department of Internal Medicine, University of Modena and Reggio Emilia, Italy.
Mod Pathol 1997 May;10(5):510-4
Department of Pathology, University of Michigan Medical Center, Ann Arbor, USA.
Spindle epithelial tumor with thymus-like differentiation (SETTLE) is a rare and distinctive low-grade neoplasm of thymic or related branchial pouch differentiation. The tumor usually presents in the thyroid or lateral neck of children and adolescents and could mimic spindle-cell carcinoma, synovial sarcoma, or malignant teratoma. We report the clinical, cytologic, histologic, immunohistochemical, and ultrastructural features of a SETTLE present for 10 years in a 15-year-old boy. Read More
Am J Surg Pathol 2001 Nov;25(11):1424-8
Hospital de la Santa Creu i Sant Pau, Barcelona, Spain.
Solitary fibrous tumor is a soft tissue neoplasm initially described in the pleura but subsequently reported in a wide variety of locations. The clinical behavior is usually benign, but the existence of aggressive cases has been documented both in the pleura and in extrapleural sites. In this report clinical and pathologic features of seven solitary fibrous tumors of the thyroid gland are presented. Read More
Arch Pathol Lab Med 2004 Jan;128(1):87-9
Department of Pathology, The Mount Sinai School of Medicine, The Mount Sinai New York University Medical Center, New York, NY 10029, USA.
Spindle cells are not routinely encountered in the context of thyroid pathology and are most often present in anaplastic thyroid carcinoma, medullary thyroid carcinoma, and benign conditions such as Riedel struma or de Quervain granulomatous thyroiditis. Only a few publications have reported papillary thyroid carcinoma admixed with a prominent spindle cell component. While these tumors are clearly distinct from anaplastic thyroid carcinoma, prognostication as to their oncologic potential is not yet established. Read More
Pathology 2004 Apr;36(2):196-211