Eur J Dermatol 2006 Mar-Apr;16(2):181-3
Department of Dermatology, M. Bufalini Hospital, Viale Ghirotti, 286, 47023 Cesena, Italy.
Ann Dermatol Venereol 2009 Apr 26;136(4):346-9. Epub 2009 Feb 26.
Service de dermatologie, CHU Saint-Jacques, 2, place Saint-Jacques, 25000 Besançon cedex, France.
Background: Infantile myofibromatosis (IM) is the most common fibrous disorder of infancy and childhood. It is characterized by congenital tumours of the skin, striated muscle, bones and viscera. Most cases are sporadic and few familial cases have been reported. Read More
Int J Pediatr Otorhinolaryngol 1998 Oct;45(3):249-54
Department of Otolaryngology-Head and Neck Surgery, Emory University, Atlanta, GA 30322, USA.
Infantile myofibromatosis (IM) is a rare tumor of infancy and childhood, typically presenting as a firm, nodular mass involving soft tissue, bone or viscera. Approximately one-third of cases involve the head and neck. These tumors can be solitary or multicentric. Read More
Med J Malaysia 2001 Dec;56(4):497-9
Department of Paediatrics, University of Malaya Medical Centre, Kuala Lumpur.
Infantile myofibromatosis (IMF) is a rare tumour with a wide spectrum of disease activity ranging from a solitary cutaneous nodule through to a multicentric form with widespread visceral involvement. It is characterised by its unique ability to spontaneously regress and has a typical histological appearance of actin-positive fibroblasts arranged in whorls or fascicles and vessels in a pericytomatous pattern. A male infant with multiple lesions involving the subcutaneous tissue and bone from birth is described and followed-up for two years. Read More
Pediatrics 1999 Jul;104(1 Pt 1):113-5
Department of Medicine, Division of Dermatology, University of Louisville, KY 40202, USA.
Background: Infantile myofibromatosis is marked by the development of firm, discrete, flesh-colored to purple nodules in skin, muscle, bone, and/or subcutaneous tissues. In cases without visceral involvement, the prognosis is excellent with expected spontaneous regression of nodules in 1 to 2 years. Visceral lesions are associated with significant morbidity and mortality generally within the first few months of life secondary to obstruction of a vital organ, failure to thrive, or infection. Read More