Clin Chem 2006 Feb 8;52(2):303-6. Epub 2005 Dec 8.
Department of Microbiology, The University of Hong Kong, Hong Kong SAR.
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Evid Based Ment Health 2018 Nov 9;21(4):139-144. Epub 2018 Oct 9.
Department of Paediatric Intensive Care, St Mary's Hospital, Imperial College Healthcare NHS Trust, London, UK.
Background: Survivors of critical illness in childhood commonly display subsequent psychiatric symptoms including emotional and behavioural difficulties, and manifestations of post-traumatic stress disorder (PTSD). Anomalies in inflammatory profiles are an established finding in these childhood psychiatric conditions.
Objective: This exploratory study aimed to investigate whether abnormal peripheral blood inflammatory markers measured during paediatric intensive care unit (PICU) admission were associated with psychiatric symptoms after discharge. Read More
Org Biomol Chem 2018 Sep;16(35):6430-6437
National Institute for Interdisciplinary Science and Technology (CSIR), Thiruvananthapuram-19, India.
A palladium-catalyzed aminocarbonylation strategy exploiting chloroform as a CO source has been developed for the synthesis of biologically potent 2-amidoimidazopyridine scaffolds. The aminocarbonylation reaction was found to be general with a range of amines and substituted imidazopyridines. Preliminary biological evaluation of cytotoxicity on selected examples provides scope for future investigations. Read More
Angiogenesis 2018 May 13;21(2):267-285. Epub 2018 Jan 13.
Department of Ophthalmology, Institute for Clinical and Experimental Medicine, Faculty of Health Sciences, Linköping University, 58183, Linköping, Sweden.
Corneal neovascularization is a sight-threatening condition caused by angiogenesis in the normally avascular cornea. Neovascularization of the cornea is often associated with an inflammatory response, thus targeting VEGF-A alone yields only a limited efficacy. The NF-κB signaling pathway plays important roles in inflammation and angiogenesis. Read More
J Exp Clin Cancer Res 2017 10 26;36(1):150. Epub 2017 Oct 26.
Department of Obstetrics and Gynecology, Hokkaido University School of Medicine, Hokkaido University, Sapporo, 0608638, Japan.
Background: Although previous studies have shown promise for targeting Musashi RNA-binding protein 2 (MSI-2) in diverse tumors, the role and mechanism of MSI-2 for cervical cancer (CC) progression and the regulation of MSI-2 expression remains unclear.
Methods: Using gene expression and bioinformatic analysis, together with gain- and loss-of-function assays, we identified MSI-2 as a novel oncogenic driver and a poor prognostic marker in CC. We explored the regulation of c-FOS by MSI-2 via RNA-immunoprecipitation and luciferase assay, and confirmed a direct inhibition of MSI-2 by miR-143/miR-107 using luciferase assay. Read More
J Obstet Gynaecol India 2014 Dec 11;64(Suppl 1):92-4. Epub 2013 Apr 11.
Department of RT & Oncology, Cama & Albless Hospital, Mahapalika Marg, Mumbai, 400001 Maharashtra India.