Regular abdominal pain and fever in each menstruation onset: an unusual menses-associated familial Mediterrenean fever attacks and a favor result on colchicine treatment.

Rheumatol Int 2006 Jun 23;26(8):760-1. Epub 2005 Sep 23.

Department of Clinical Immunology and Rheumatology, Ankara University, School of Medicine, Ankara, Turkey.

We present a 38-year-old woman suffering from regular abdominal pain and fever only in each menstruation onset for 7 years. The clinical symptoms, along with inflammatory findings during painful attacks, the beneficial effect of colchicine and genetic mutation (M694 V and M680I) supported the diagnosis of familial Mediterranean fever (FMF). A literature review indicated that FMF attacks occurring only during menstruation are rarely seen. This clinical picture may be confused with gynecological disorders especially in the people of Mediterranean origin.

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http://dx.doi.org/10.1007/s00296-005-0055-6DOI Listing
June 2006
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