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PLoS Pathog 2023 Jun 8;19(6):e1011425. Epub 2023 Jun 8.

BioMEMS Resource Center, Center for Engineering in Medicine and Surgery, Department of Surgery, Massachusetts General Hospital, Harvard Medical School, and Shriners Children`s Boston, Boston, Massachusetts, United States of America.

Cryptosporidium hominis is a serious cause of childhood diarrhea in developing countries. The development of therapeutics is impeded by major technical roadblocks including lack of cryopreservation and simple culturing methods. This impacts the availability of optimized/standardized singular sources of infectious parasite oocysts for research and human challenge studies. Read More

Front Cell Infect Microbiol 2023 22;13:1178576. Epub 2023 May 22.

School of Veterinary Science, Hopkirk Research Institute, Massey University, Palmerston North, New Zealand.

Cryptosporidiosis is a worldwide diarrheal disease caused by the protozoan . The primary symptom is diarrhea, but patients may exhibit different symptoms based on the species of the parasite they are infected with. Furthermore, some genotypes within species are more transmissible and apparently virulent than others. Read More

PLOS Glob Public Health 2023 30;3(5):e0001527. Epub 2023 May 30.

Institute of Environmental Science and Research Ltd. (ESR), Christchurch, New Zealand.

Cryptosporidium and Giardia are major causes of diarrhoea globally, and two of the most notified infectious diseases in New Zealand. Diagnosis requires laboratory confirmation carried out mostly via antigen or microscopy-based techniques. However, these methods are increasingly being superseded by molecular techniques. Read More

Environ Monit Assess 2023 Mar 22;195(4):499. Epub 2023 Mar 22.

Cellular and Molecular Research Center, Cellular and Molecular Medicine Research Institute, Urmia University of Medical Sciences, Urmia, Iran.

Cryptosporidium is an obligate intracellular parasite reported from all over the world. This protozoan infects a wide range of animals as well as humans. Cryptosporidium parvum and Cryptosporidium hominis are the most prevalent infecting species with mild and self-limiting infection in healthy people. Read More

Microbiol Spectr 2023 Feb 23;11(1):e0392122. Epub 2023 Jan 23.

Parasitology Laboratory, New York State Department of Health, Albany, New York, USA.

Watersheds that supply residents with drinking water have the potential for contamination with oocysts. To evaluate any potential similarities between species previously found in the New York City (NYC) watershed and those causing disease in NYC, the species were identified in stool specimens from residents with cryptosporidiosis. Genetic analysis was performed on 628 positive stool samples collected from NYC residents between 2015 and 2018 to determine the species present. Read More