Visual outcome of juvenile rheumatoid arthritis-associated uveitis in adults.

Ocul Immunol Inflamm 2005 Feb;13(1):33-8

McGill University, Department of Ophthalmology, Uveitis Service Montréal Canada.

Purpose: Juvenile rheumatoid arthritis (JRA) is the systemic disease most frequently associated in childhood uveitis. The disease may cause several ocular complications, visual impairment, and blindness. Recent studies revealed a more favorable ocular prognosis. Our purpose was to analyze the long-term visual outcome of JRA-associated uveitis.

Methods: Ocular complications and visual outcome in adult patients with JRA-associated uveitis were evaluated. Among 18 patients included in the study, uveitis was bilateral in 12 (66.7%) and unilateral in six (33.3%), for a total of 30 eyes with ocular involvement.

Results: The mean durations of JRA and its associated uveitis were 24.9 and 20.5 years, respectively. All eyes (100%) had at least one ocular complication. The most frequently observed ocular complications were cataract (83.3%), band keratopathy (60%), posterior synechia (46.7%), glaucoma (33.3%), hypotony (16.7%), and macular pathology (13.3%). Final visual acuity was impaired in 40% of the eyes, poor in 20%, and totally lost in 10%. Therefore, 70% of the eyes were either visually handicapped or totally blind. Most eyes underwent at least one surgical procedure. Inflammation was active at last examination in 63.3% of eyes. All patients were still treated topically and with systemic NSAID. Sixty-one percent of the patients were using an immunosuppressive agent.

Conclusion: JRA-associated uveitis still has a severe course and blinding potential. Patients suffer from uveitis and its complications even during the adulthood period. However, because our series represents a more severe subset of the disease, the outcome may be poorer than that of some other outcome studies.

Download full-text PDF

Source Listing
February 2005
Get 20% Off Journals at

Similar Publications

Incidence, risk factors and complications of ocular graft-versus-host disease following hematopoietic stem cell transplantation: Incidence, risk factors and complications of ocular GVHD.

Am J Ophthalmol 2021 Feb 21. Epub 2021 Feb 21.

IRCCS Azienda Ospedaliero Universitaria di Bologna, Bologna, Italy.

Purpose: The purpose of this research was to evaluate the incidence, risk factors and complications of ocular graft-versus-host disease (GVHD) in a large single center study.

Design: Retrospective observational case series.

Methods: This study included 283 patients who underwent hematopoietic stem cell transplantation (HSCT) between 2005 and 2020. Read More

View Article and Full-Text PDF
February 2021

Scleral Fixation of Carlevale Intraocular Lens in Children: A Novel Tool in Correcting Aphakia With No Capsular Support.

Ophthalmic Surg Lasers Imaging Retina 2021 Feb;52(2):94-101

Background And Objective: To report the clinical outcomes of the use of a novel, specially designed, scleral-fixated intraocular lens (IOL) for the correction of aphakia in the absence of capsular support of variable etiology in children.

Patients And Methods: This is a retrospective, noncomparative, interventional case series of five eyes of five consecutive patients who underwent three-port pars plana vitrectomy and scleral fixation of the IOL. Inclusion criteria were at least 6 months of follow-up in children who underwent vitrectomy and IOL placement for aphakia and inadequate capsular support. Read More

View Article and Full-Text PDF
February 2021

Ocular complications of perioperative anesthesia: a review.

Graefes Arch Clin Exp Ophthalmol 2021 Feb 24. Epub 2021 Feb 24.

Advanced Eye Center, Department of Ophthalmology, Post Graduate Institute of Medical Education and Research (PGIMER), Sector 12, Chandigarh, 160012, India.

Ocular complications associated with anesthesia in ocular and non-ocular surgeries are rare adverse events which may present with clinical presentations vacillating between easily treatable corneal abrasions to more serious complication such as irreversible bilateral vision loss. In this review, we outline the different techniques of anesthetic delivery in ocular surgeries and highlight the incidence and etiologies of associated injuries. The changes in vision in non-ocular surgeries are mistaken for residual sedation or anesthetics, therefore require high clinical suspicion on part of the treating ophthalmologists, to ensure early diagnosis, adequate and swift management especially in surgeries such as cardiac, spine, head and neck, and some orthopedic procedures, that have a comparatively higher incidence of ocular complications. Read More

View Article and Full-Text PDF
February 2021

Clinical features of childhood uveitis at a tertiary referral center in Southern Turkey.

Int Ophthalmol 2021 Feb 24. Epub 2021 Feb 24.

School of Medicine, Department of Ophthalmology, Cukurova University, Adana, Turkey.

Purpose: To report the epidemiology, etiology, ocular characteristics, management, and visual outcomes of pediatric uveitis patients in Southern Turkey.

Methods: The clinical records of pediatric patients with a diagnosis of uveitis under the age of 16 years and followed up longer than 6 months were analyzed retrospectively.

Results: The study included 102 patients and 173 affected eyes. Read More

View Article and Full-Text PDF
February 2021

Long-term outcomes following primary versus secondary Boston keratoprosthesis type 1 implantation.

Br J Ophthalmol 2021 Feb 23. Epub 2021 Feb 23.

Department of Ophthalmology, Centre Hospitalier de l'Université de Montréal, Montreal, Quebec, Canada.

Background/aims: To compare long-term outcomes of primary versus secondary (postgraft failure) Boston keratoprosthesis type 1 (KPro) implantation.

Methods: Medical records of patients at the Centre hospitalier de l'Université de Montréal having undergone KPro implantation between 2008 and 2017 were reviewed and included if they had a preoperative Snellen best-corrected visual acuity (BCVA) of 20/100 or worse and a minimum of 5 years of follow-up. Eighty-two eyes were separated into two cohorts (40 primary, 42 secondary KPro) and BCVA, complications and device retention were evaluated between groups. Read More

View Article and Full-Text PDF
February 2021