Biol Psychol 2005 Apr 29;69(1):5-21. Epub 2004 Dec 29.
Department of Psychiatry, University of North Carolina, CB 7175 Medical Building A, Chapel Hill, NC 27599-7175, USA.
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Psychosom Med 2005 Jul-Aug;67(4):531-8
Department of Psychiatry, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.
Objective: We examined whether the magnitude of plasma oxytocin (OT), norepinephrine (NE), cortisol, and blood pressure (BP) responses before and after a brief episode of warm contact (WC) with the spouse/partner may be related to the strength of perceived partner support.
Methods: Subjects were 38 cohabiting couples (38 men, 38 women) aged 20 to 49 years. All underwent 10 minutes of resting baseline alone, 10 minutes of WC together with their partner, and 10 minutes of postcontact rest alone. Read More
Horm Behav 2005 May;47(5):540-8
School of Medicine, University of North Carolina at Chapel Hill, NC 27599-7175, USA.
Estrogen administration results in increased release of the oxytocin (OT) prohormone reflected by increases in oxytocin intermediate peptide (OT Int) in both animal models and humans, and sequential treatment of ovariectomized rats with estrogen/progesterone then progesterone withdrawal leads to increased hypothalamic OT mRNA. Blood pressure (BP) reductions have been related to increased exogenous and endogenous OT in rats and to higher endogenous OT activity in premenopausal women, but not previously in postmenopausal women. Thus, we used plasma obtained at rest and during a speech stressor from 54 postmenopausal women who participated in a 6-month randomized trial of oral conjugated estrogens vs. Read More
Psychoneuroendocrinology 2011 Sep 19;36(8):1249-56. Epub 2011 Apr 19.
Department of Psychology, Brigham Young University, Provo, UT 84602, United States.
Oxytocin (OT) activity increases in response to stress as well as to warm social contact. Subclinical depression is associated with higher stress but less reward from social contacts. The present investigation was intended to examine whether husbands and wives with high depressive symptomatology scores have increased plasma and salivary OT that may be mediated partly by higher perceived stress, and also to assess whether an intervention to convey partner support through "warm touch" may reduce effects of depressive symptoms on OT. Read More
Health Psychol 2000 Nov;19(6):560-7
Department of Psychiatry, University of North Carolina at Chapel Hill, 27599-7175, USA.
The neuropeptide oxytocin (OT) enhances maternal behavior and decreases blood pressure (BP) and stress responses in animals. Thus, the relationship of OT responsivity to BP in 14 breast- and 11 bottle-feeding mothers of infants was examined. Laboratory BP was assessed during baseline, speech preparation, active speech, and recovery on 2 days, 1 in which baseline and speech were separated by 10 min of baby holding and the other by no baby contact. Read More