Frequency-dependent transversal flow control in centrifugal microfluidics.

Authors:
Thilo Brenner
Thilo Brenner
IMTEK-University of Freiburg
Freiburg | Germany
Thomas Glatzel
Thomas Glatzel
Institute for Medical Microbiology and Immunology
Germany
Roland Zengerle
Roland Zengerle
University of Freiburg
Germany
Dr. Jens Ducree, Dr. rer. nat. habil. Dipl. Phys.
Dr. Jens Ducree, Dr. rer. nat. habil. Dipl. Phys.
Fraunhofer Project Centre at Dublin City University
Professor (Full)
microfluidics, Lab-on-a-Chip, hydrodynanmics, business development, project management, organisational leadership
Glasnevin, Dublin 9 | Ireland

Lab Chip 2005 Feb 14;5(2):146-50. Epub 2004 Oct 14.

IMTEK-University of Freiburg, Laboratory for MEMS Applications, Georges-Koehler-Allee 106, D-79110 Freiburg, Germany.

This work presents a novel flow switch for centrifugal microfluidic platforms which is solely controlled by the Coriolis pseudo force. This Coriolis switch consists of an inverse Y-structure with one common upstream channel and two symmetric outlets on a rotating disk. Above a certain threshold frequency, the Coriolis force becomes dominant that the entire flow is diverted into one of the outlets which is selected by the direction of rotation. The threshold frequency has been measured to be 350 rad s(-1)(approximately 55.7 Hz) for a channel width of 360 microm and a depth of 125 microm. The results are supported by extensive CFD simulations.

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February 2005
4 Reads
3 PubMed Central Citations(source)

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