Fundus pigment distribution in rhesus monkeys.

Vet Ophthalmol 2004 Nov-Dec;7(6):391-6

Department of Ophthalmology, University of Florida, Box 100284, Gainesville, FL 32610-0284, USA.

There is growing evidence for an interaction among fundus pigmentation, character, geography and the function and structure of the outer retina. We examined three inbred groups of rhesus macaques (132 eyes) including all ages. One was a smaller (18 eyes) group. Coat colors were variations of brown-tan however, the smaller group had lighter 'golden' coats and colors. Fundus images were classified for pigmentation and its geographic distribution. In golden-coated animals there was bias toward nasal fundus hypopigmentation with the optic disk as a watershed demarcation zone, which extended in the superior-inferior direction. Temporal fundus hypopigmentation did not occur in the absence of nasal hypopigmentation. More common, darker coated samples showed a characteristic diffuse fundus pigmentation. There was no evidence for albinism or large variations in macular pigmentation. Rhesus monkeys can exhibit geographically controlled genetic development of fundus pigmentation. Hypopigmentation provides for access to the choroidal infrastructure.

Download full-text PDF

Source
http://dx.doi.org/10.1111/j.1463-5224.2004.04042.xDOI Listing
January 2005
7 Reads

Publication Analysis

Top Keywords

fundus pigmentation
12
fundus hypopigmentation
8
rhesus monkeys
8
fundus
7
pigmentation
5
hypopigmentation optic
4
optic disk
4
smaller group
4
hypopigmentation
4
nasal fundus
4
disk watershed
4
watershed demarcation
4
superior-inferior direction
4
direction temporal
4
extended superior-inferior
4
zone extended
4
demarcation zone
4
bias nasal
4
animals bias
4
images classified
4

Similar Publications