Search Our Scientific Publications & Authors

Diabetes Metab Syndr 2021 Feb 23;15(2):487-491. Epub 2021 Feb 23.

Arkadi M. Rywlin M.D. Department of Pathology and Laboratory Medicine, Mount Sinai Medical Center, Miami Beach, FL, USA; Herbert Wertheim College of Medicine, Florida International University, Miami, FL, USA.

Background And Aims: Diabetes mellitus (DM) is a chronic metabolic disease associated with long-term multisystem complications, among which nonhealing diabetic foot ulcers (DFUs) are recognized as major cause of morbidity and mortality. Treating DFUs with surgical procedures such as synthetic or biological skin grafts or skin substitutes has several limitations, where none of the currently available skin substitutes is ideal.

Methods: OVID/Medline and PubMed databases were searched using the Medical Subject Heading (MeSH) or Title/Abstract words ("diabetic foot ulcers", "skin substitutes", and "nanofibers"), to identify published research studies on DFUs and nanofibers. Read More

Clin Neurol Neurosurg 2021 Feb 18;203:106565. Epub 2021 Feb 18.

Department of Neurology, Yale University School of Medicine, New Haven, CT, 06510, USA.

Background: Although spinal cord injury (SCI) is a major cause of disability, current therapeutic options remain limited. Recent progress in cellular therapy with mesenchymal stem cells (MSCs) has provided improved function in animal models of SCI. We investigated the safety and feasibility of intravenous infusion of MSCs for SCI patients and assessed functional status after MSC infusion. Read More

Phytomedicine 2021 Jan 29;84:153484. Epub 2021 Jan 29.

Genotoxicity Laboratory, Division of Toxicology and Experimental Medicine, Lucknow 226031, Uttar Pradesh, India. Electronic address:

Background: Celecoxib (CXB), a selective COX-2 inhibitor NSAID, has exhibited prominent anti-proliferative potential against numerous cancers. However, its low bioavailability and long term exposure related cardiovascular side effects, limit its clinical application. In order to overcome these limitations, natural bioactive compounds with lower toxicity profile are used in combination with therapeutic drugs. Read More

Stem Cell Res 2021 Feb 24;53:102269. Epub 2021 Feb 24.

Department of Child and Adolescent Psychiatry and Psychotherapy, Psychiatric Hospital, University of Zurich, Zurich, Switzerland; Neuroscience Center Zurich, University of Zurich and the ETH Zurich, Zurich, Switzerland; Zurich Center for Integrative Human Physiology, University of Zurich, Switzerland. Electronic address:

Ten human induced pluripotent stem cell (iPSC) lines have been derived from five healthy controls matched to a study including Attention-Deficit Hyperactivity Disorder patients (ADHD). Both female and male children and adolescents aged 6-18 years were recruited. Isolated keratinocyte cells from the participants were reprogrammed into iPSCs using non-integrating Sendai virus to deliver the reprogramming factors Oct3/4, Sox2, Klf4 and cMyc. Read More

Ecotoxicol Environ Saf 2021 Mar 2;214:112097. Epub 2021 Mar 2.

Tianjin Key Laboratory of Animal and Plant Resistance, College of Life Sciences, Tianjin Normal University, China. Electronic address:

Plant ZIP genes represent an important transporter family and may be involved in cadmium (Cd) accumulation and Cd resistance. In order to explore the function of SmZIP isolated from Salix matsudana, the roles of SmZIP in Cd tolerance, uptake, translocation, and distribution were determined in the present investigation. The transgenic SmZIP tobacco was found to respond to external Cd stress differently from WT tobacco by exhibiting a higher growth rate and more vigorous phenotype. Read More