Mammary myofibroblastoma: report of two cases with fine-needle aspiration cytology and review of the cytology literature.

Diagn Cytopathol 2004 Jun;30(6):406-10

Lac Laboratorio de Anatomia Patologica e Citopatologia, Campo Grande, Mato Grosso do Sul, Brazil.

Fine-needle aspirates from two histologically, immunohistochemically, and ultrastructurally confirmed mammary myofibroblastomas (MM) of two elderly women revealed abundant, randomly arranged single and clustered benign spindle-shaped mesenchymal cells with scant cytoplasm and elongated or oval nuclei displaying a finely granular chromatin pattern and inconspicuous nucleoli. In one case a few cells showed inconspicuous nuclear grooves. The aspirated tumor cells from the other case stained positively with desmin and CD34 antibodies and negatively with cytokeratin and S-100 protein antibodies, in keeping with an MM. A review of the literature was briefly presented.

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http://dx.doi.org/10.1002/dc.20042DOI Listing
June 2004
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