Effects of alpha-pinene odor in different concentrations on stress-induced hyperthermia in rats.

J Vet Med Sci 2003 Sep;65(9):1023-5

Laboratory of Veterinary Ethology, The University of Tokyo, Japan.

Stress-induced hyperthermia is observed in animals exposed to stressful conditions. In our previous study, plant-derived fragrances such as green odor and alpha-pinene were shown to suppress this stress response in rats. In the present study, we examined the concentration-dependence of the alpha-pinene effects on stress-induced hyperthermia. Male rats carrying telemetry transmitters were transferred individually to a new cage containing bedding that had been sprayed with 0.3, 0.03, and 0.003% concentrations of alpha-pinene or control solvent. Following transfer to the novel environment, the body temperature increased significantly, and this response was clearly suppressed when the cage was scattered with 0.03% alpha-pinene only. These results suggest that the effect of alpha-pinene on stress-induced hyperthermia can be observed only at a certain concentration.

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http://dx.doi.org/10.1292/jvms.65.1023DOI Listing
September 2003
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