Redecoration of apartments promotes obstructive bronchitis in atopy risk infants--results of the LARS Study.

Int J Hyg Environ Health 2003 Jun;206(3):173-9

Centre for Environmental Research, Department of Human Exposure Research and Epidemiology, Permoser Strasse 15, D-04318 Leipzig, Germany.

Findings by other authors indicate that exposure to chemical emissions from indoor paint is related to asthma symptoms in adults. In their first years of life children are receptive to obstructive airway diseases. The aim of this study was to investigate the influence of redecoration of the apartment on airway symptoms in infants during the first two years of life. The Leipzig Allergy Risk Children Study (LARS) is a birth cohort study with the following inclusion criteria: double positive family atopy anamnesis, cord blood IgE > 0.9 kU/l, or low birth weight between 1500-2500 g. Within the context of LARS, 186 parents of risk children completed a questionnaire on the respiratory symptoms of their children and the redecoration of their apartment at the end of the first and second year of life. A total 22% of the children suffered from obstructive bronchitis once or more during their first year, and 11% experienced this condition during their second year of life. Redecoration of the apartment had a significant influence on the appearance of obstructive bronchitis in the first (OR 4.1 95% CI 1.4-11.9) and in the second year of life (OR 4.2 95% CI 1.4-12.9). (The OR are adjusted for cord blood-IgE > 0.9 kU/l, birth weight < or = 2500 g, male sex and double positive parental atopy anamnesis, dampness, smoking or pet in the apartment). Simultaneous contamination from redecoration activities and additional exposures such as smoking, a pet or dampness in the apartment increased the risk for obstructive bronchitis in the first year (OR 9.1; 95% CI 2.3-34.8) as well as in the second year (OR 5.1; 95% CI 1.6-15.6). Our data suggest that redecoration of the apartment is associated with the development of acute inflammations, but not with a chronic influence on the airways in atopy risk infants. At an exposure to more than one environmental factor, pronounced effects were seen.

Download full-text PDF

Source
http://dx.doi.org/10.1078/1438-4639-00218DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7129632PMC
June 2003
Get 20% Off Journals at LWW.com

Similar Publications

Effects of indoor painting and smoking on airway symptoms in atopy risk children in the first year of life results of the LARS-study. Leipzig Allergy High-Risk Children Study.

Int J Hyg Environ Health 2000 Mar;203(1):23-8

Centre of Environmental Research, Department of Human Exposure Research and Epidemiology, Leipzig, Germany.

Introduction: The Leipzig Allergy High-Risk Children Study (LARS) is a prospective nested cohort control study about the influence of chemical indoor exposure in dwellings on the health outcome of atopy-risk children during the first years of life.

Design And Methods: 475 premature children and children with allergic risk factors have been selected out of the 1995/1996 birth cohort in the city of Leipzig. Twenty-five volatile organic compounds (VOC) were measured in the infant's bedrooms using passive sampling systems for 4 weeks after birth. Read More

View Article and Full-Text PDF
March 2000

Association between indoor renovation activities and eczema in early childhood.

Int J Hyg Environ Health 2006 May 21;209(3):241-7. Epub 2006 Feb 21.

Department of Human Exposure Research and Epidemiology, UFZ Leipzig-Halle, Permoserstrasse 15, 04318 Leipzig, Germany.

Background: Other factors besides a genetic disposition seem to play a role in the development of allergic disorders. Exposure to risk factors such as indoor air pollution is becoming increasingly interesting, especially during early childhood.

Methods: Within an epidemiological study (LISS: Leipzig infection, allergy and airway diseases study among school starters, involving 2536 children, birth cohort 1991/92, carried out in 1997/98) the effect of indoor exposure on physician-confirmed eczema and allergic symptoms has been investigated. Read More

View Article and Full-Text PDF
May 2006

Chronic bronchitis and airflow obstruction is associated with household cooking fuel use among never-smoking women: a community-based cross-sectional study in Odisha, India.

BMC Public Health 2018 07 27;18(1):924. Epub 2018 Jul 27.

Center for Environmental and Occupational Health, AIPH University, Bhubaneswar, India.

Background: The use of solid biomass as cooking fuel could be a potential risk factor for chronic bronchitis (CB) and airflow obstruction (AFO) among never-smoking women. The disease burden in India among women is generally underestimated due to limited population-based epidemiological investigations. The aim of the study was to determine the prevalence of CB and AFO among never-smoking women, and its association with household cooking fuel use. Read More

View Article and Full-Text PDF
July 2018

Indoor exposure to environmental tobacco smoke and dampness: respiratory symptoms in Sardinian children--DRIAS study.

Environ Res 2009 Jan 25;109(1):59-65. Epub 2008 Oct 25.

Department of Animal and Human Biology, University La Sapienza, Piazz. Le A. Moro 5, 00185 Rome, Italy.

Indoor exposures at home, environmental tobacco smoke (ETS) and mould/dampness adversely affect respiratory health of children. Disturbi Respiratori nell'Infanzia e Ambiente in Sardegna (DRIAS) (Respiratory Symptoms in children and the Environment in Sardegna, Italy) aims at relating the prevalence of respiratory and allergic symptoms to indoor exposures in Sardinian children. DRIAS, a cross-sectional investigation of respiratory symptoms/diseases, used a modified version of ISAAC questionnaire, included 4122 children attending 29 primary schools in the school year 2004-2005. Read More

View Article and Full-Text PDF
January 2009