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Front Med (Lausanne) 2021 17;8:547849. Epub 2021 Feb 17.

Department of Immunology, University Clinical Hospital Virgen de la Arrixaca-Biomedical Research Institute of Murcia (IMIB), Murcia, Spain.

Antibody-mediated rejection (AMR) is the major cause of kidney transplant rejection. The donor-specific human leukocyte antigen (HLA) antibody (DSA) response to a renal allograft is not fully understood yet. mTOR complex has been described in the accommodation or rejection of transplants and integrates responses from a wide variety of signals. Read More

Int J Legal Med 2021 Mar 6. Epub 2021 Mar 6.

Department of Forensic Science, School of Basic Medical Sciences, Central South University, No:172, Tongzipo Road, Changsha, 410013, Hunan, People's Republic of China.

Burkina Faso (BF) is a landlocked Sahelian country located in the middle of West Africa. Sixty-three local languages are spoken in BF. Despite this high diversity, the BF population remains poorly investigated, and updated forensic parameters with a large number of Y chromosome short tandem repeats (Y-STRs) are still missing. Read More

Talanta 2021 May 18;226:122115. Epub 2021 Jan 18.

Department of Chemistry, National Chung Hsing University, 250, Kuo Kuang Rd., Taichung, 402, Taiwan. Electronic address:

An antibody conjugated boronic acid modified silver chip (ABAS ship) is fabricated as a simple, rapid, accurate, sensitive and cost-effective sample preparation method for abused drug quantification in human urine. Ketamine, one common abused drug, was applied as proof of concept for ABAS chip with high resolution matrix-assisted laser desorption ionization time-of-flight mass spectrometer (MALDI-TOF MS) analysis. The overall testing process required 10 min at part per billion (ppb) sensitivity level, where current drug testing method necessitated several hours with similar sensitivity. Read More

Micromachines (Basel) 2021 Feb 27;12(3). Epub 2021 Feb 27.

Life Science Interface Group, Tyndall National Institute, University College Cork, T12 R5CP Cork, Ireland.

Capillary electrochromatography (CEC) is a separation technique that hybridizes liquid chromatography (LC) and capillary electrophoresis (CE). The selectivity offered by LC stationary phase results in rapid separations, high efficiency, high selectivity, minimal analyte and buffer consumption. Chip-based CE and CEC separation techniques are also gaining interest, as the microchip can provide precise on-chip control over the experiment. Read More

Insects 2021 Feb 17;12(2). Epub 2021 Feb 17.

Department of Life Sciences, Natural History Museum, London SW7 5BD, UK.

Research is a vital component of all forensic sciences and is often stimulated by casework, which identifies gaps in our knowledge. In such a niche area of forensic science as entomology there should be a close and mutually beneficial relationship between research and casework: to some extent there is a continuum between the two and many forensic entomologists are involved in both to a greater or lesser degree. However, research and casework involve quite differing challenges, from the replicated, highly controlled, sometimes esoteric aspects of research to the very individual, sometimes chaotic and disruptive, but highly applied aspects of casework. Read More