Aust Vet J 2001 Dec;79(12):808-17
Department of Veterinary Clinical Sciences, Faculty of Veterinary Science, The University of Sydney, New South Wales.
Jpn J Clin Oncol 1999 Jul;29(7):340-8
Mie University School of Medicine, Tsu, Japan.
Background: Patients with acute lymphocytic leukemia (ALL) and those with lymphoblastic lymphoma (LBL) have overlapping clinical and immunophenotypic features and they have been treated with the same or very similar chemotherapy regimens. The goal of this multi-institutional phase II trial was to evaluate the therapeutic efficacy of a short-term, six-drug chemotherapy regimen for adult patients with untreated ALL or LBL.
Methods: Forty-six eligible patients, 41 with ALL and five with LBL, were treated with a short-term (planned total therapy duration; 36-38 weeks), simplified chemotherapy program; two courses of VEPA-L (vincristine, cyclophosphamide, prednisolone, doxorubicin, I-asparaginase plus intrathecal methotrexate and prednisolone) followed by four courses of M-VEPA (methotrexate plus VEPA), without the traditional maintenance therapy using daily 6-mercaptopurine and weekly methotrexate. Read More
J Am Vet Med Assoc 1998 Oct;213(8):1144-9
Veterinary Medical Teaching Hospital, School of Veterinary Medicine, University of California, Davis 95616-8734, USA.
Objective: To determine clinical and pathologic findings in cats with alimentary malignant lymphoma and results of treatment with a combination of prednisone, L-asparaginase, vincristine, cyclophosphamide, doxorubicin, and methotrexate.
Design: Retrospective study.
Animals: 21 cats with alimentary malignant lymphoma. Read More
Ann Hematol 2001 Nov;80(11):647-52
Department of Medicine, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan, Republic of China.
Lymphoblastic lymphoma (LBL) frequently affects young adults and usually presents with a mediastinal mass as well as bone marrow involvement. Although the frequency of LBL in the Far East is higher than that of Western countries, no reports regarding treatment of this disease have as yet been reported. We herein report our treatment experience and verify the efficacy of the Stanford/Northern California Oncology Group (NCOG) protocol for this disease and recommend treatment strategies for LBL patients. Read More
Aust Vet J 1999 Jul;77(7):442-4
Children's Cancer Research Institute, Sydney Children's Hospital, Randwick, New South Wales.
Objective: To determine the efficacy of doxorubicin when used alone in inducing remission in cats with lymphosarcoma.
Design: Prospective multi-institutional study of naturally occurring disease.
Methods: Cases were accrued from veterinary institutions in Australia and New Zealand after obtaining consent from informed owners. Read More