MD, PhD VANIA PIATTO, MD, PhD - Faculdade de Medicina de São José do Rio Preto - PROF DR

MD, PhD VANIA PIATTO

MD, PhD

Faculdade de Medicina de São José do Rio Preto

PROF DR

Sao Jose do Rio Preto, SP | Brazil

Main Specialties: Medical Genetics, Neonatal-Perinatal Medicine, Otology - Neurotology, Pediatric Otolaryngology, Pediatrics

ORCID logohttps://orcid.org/0000-0003-2677-8243


Top Author

MD, PhD VANIA PIATTO, MD, PhD - Faculdade de Medicina de São José do Rio Preto - PROF DR

MD, PhD VANIA PIATTO

MD, PhD

Introduction

Graduated in Medicine from the Regional Medical School Foundation of Sao Jose do Rio Preto (1989), and Housing Specialist in Pediatrics, Master of Health Sciences, Fac Med SJRio Black (1998) and Doctorate in Health Science Fac Med Rio Preto SJ (2003), Title of Proficiency in Human Anatomy by Notorious Know (2010). Professor IV-D of the Department of Anatomy, Fac Med SJRioPreto, Chairman of the Standing Committee of the Bid FAMERP, Advisor Professor of the Graduate Course in Health Sciences (FAMERP). It is part of the Bank of Examiners of SINAES (INEP) as well as the Institutional Reviewer for Undergraduate Courses Medicina and for ARCU-SUL. Experience in Medicine with emphasis in pediatrics, working mainly in the following areas: Pediatrics, Profile and prevalence of ORL diseases; Molecular biology: hearing impairment non-syndromic sensorineural, the syndrome of obstructive sleep apnea syndrome, lactose intolerance and related diseases to the ORL.Periventricular leukomalacia in preterm infants: correlation of diagnostic neuroimaging with cytokine gene polymorphisms; molecular evaluation of persistent and refractory anemia after bariatric surgery.

Primary Affiliation: Faculdade de Medicina de São José do Rio Preto - Sao Jose do Rio Preto, SP , Brazil

Specialties:


View MD, PhD VANIA PIATTO’s Resume / CV

Education

Sep 1994
FAMERP
PROF DR
MORPHOLOGY
FAMERP
PROF DR
ANATOMY

Experience

Sep 1994
Faculdade de Medicina de São José do Rio Preto
PROF DR
MORPHOLOGY
FAMERP
PROF DR
RESEARCHER

Publications

20Publications

378Reads

12Profile Views

35PubMed Central Citations

Vitamin D Deficiency And Insufficiency Levels In Patients Attended At A Healthcare Teaching-Hospital Laboratory

IJDReses.2019;9(3):26648-52

International Journal of Development Research

Aim: Characterize the Vitamin D serum profile, by means of exams done in patients, from 2012 to 2016, in a healthcare Teaching-Hospital laboratory, correlating it with gender, age range, and health care systems types-Public or Private. Material and Methods:Retrospective, registry-scan study using reports of 44,700 Vitamin D serum dosages dosages carried out in patients in routine consultations, from the age of two. Results:Female patientsdone 36,654 (82%) Vitamin D exams and male 8,046 (18%) exams.By the Public system 24,965 (55.8%) exams were performed and 19,735 (44.2%) by the Private system (p<0.005).Male patients’ age in the Public system varied from 5 to 94 years and for the Privatesystem, it varied from 2 to 75 years (p<0.005).Female patients’ age in Public system varied from 12 to 97 years and for the Private, it varied from 3 to 86 years (p<0.005).The age ranges with the highest number of requests were adult (43%) and elderly (33%).Levels of Vitamin D Deficiency and Insufficiency were found in all age levels (30.5%) except for infancy (p<0.005). Conclusion: Vitamin D Deficiency and Insufficiency levels were found, in both genders, in all age ranges, except for infancy, but with predominance in the Private system and in female gender.

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March 2019
8 Reads

Leucomalácia periventricular e correlação com citocinas pro e antiinflamatórias

Arq Cien Saude. 2018;25(1):3-5

Arquivos de Ciências da Saúde

Introdução: Polimorfismos em genes de citocinas inflamatórias (TNF-α e IL-1β) e antiinflamatórias (IL-10) intensificam a resposta inflamatória, após anóxia, aumentando as afecções decorrentes da síndrome hipóxico-isquêmica como a leucomalácia periventricular (LPV). Objetivos: Investigar a associação entre ambos os polimorfismos inflamatórios (-1031T/C no gene TNF-α e -511C/T no gene IL-1β) e o antiinflamatório (-1082G/A no gene IL-10) e a etiopatogênese/risco da LPV em neonatos com esta afecção. Material e Métodos: Estudo prospectivo de casos-controle em 50 neonatos prematuros e a termo (Grupo Casos) e em 50 neonatos a termo (Grupo Controle), de ambos os sexos. DNA foi extraído de leucócitos de sangue periférico e a análise molecular realizada pela Reação em Cadeia da Polimerase/Análise de Restrição Enzimática (PCR/RFLP). Resultados: A idade gestacional média entre casos e controles foi, respectivamente, de 31,0 semanas e 39,4 semanas (p<0,0001). O peso médio, em gramas, foi de 1561,1 para os casos e 3509,9 para controles (p<0,0001). Foi encontrada associação entre o genótipo TC (produtor intermediário de citocina inflamatória) (OR: 2.495; IC95%: 1,10-5,63; p=0,043) assim como entre os genótipos TC+CC (produtores inflamatórios intermediário+alto) (OR: 2,471; IC95%: 1,10-5,55; p=0,044) no gene TNF-α e o risco de LPV. Estatisticamente significante associação foi encontrada entre os genótipos (CT+TT) (produtores inflamatórios intermediário +alto) (OR: 23,120; IC95%: 1,31-409,4; p=0,003) no gene IL-1β e o risco de LPV. No gene IL-10, foi encontrada redução significativa do risco de LPV para o genótipo GG (alto produtor antiinflamatório) (OR: 0,07407; IC95%: 0,02-0,34; p<0,0001) assim como para o alelo G (OR: 0,5098; IC95%: 0,29-0,91; p=0,030). Conclusão: há associação entre os polimorfismos inflamatórios (-1031T/C no gene TNF-α e -511C/T no gene IL-1β) e o risco de desenvolvimento de LPV e associação entre o polimorfismo antiinflamatório (-1082G/A no gene IL-10) na proteção ao desenvolvimento da LPV, na população estudada.

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April 2018
20 Reads

PREVALÊNCIA DE HIPOTIREOIDISMO EM PACIENTES COM QUEIXAS DE DISTÚRBIOS RESPIRATÓRIOS RELACIONADOS AO SONO

Arq Cienc Saude. 2016;23:30-5.

Arquivos de Ciencias da Saude

Introdução: A síndrome da apneia obstrutiva do sono (SAOS) é um dos distúrbios respiratórios mais complexos do sono. A associação entre hipotireoidismo e a referida síndrome tem sido motivo de investigação devido à similaridade dos sintomas de ambas as afecções. Objetivo: Determinar a prevalência de hipotireoidismo em pacientes com queixas de distúrbios respiratórios relacionados a sono. Material e Métodos: Foram revisados 200 prontuários de pacientes de ambos os gêneros que foram encami-nhados para primeira consulta, ao Ambulatório de Apneia do Sono de um serviço terciário, entre os anos de 2013 e 2014, sendo coletados os seguintes dados: idade à época da realização da polissonografia, nível sérico dos hormônios tiroxina livre (T4L) e estimulante da tireoide (TSH), índice de massa corpórea (IMC) e o índice de apneia/hipopneia (IAH). Estudo de casos retrospec-tivo em corte transversal. Resultados: Foi encontrada a prevalência de 16,2% (21/130) de hipotireoidismo em pacientes com síndrome da apneia obstrutiva do sono sendo a maioria do gênero masculino e 10% (7/70) de hipotireoidismo em pacientes sem síndrome da apneia obstrutiva do sono sendo todos (100%) do gênero feminino (OR-1,734; IC95%-0,6979-4,308; χ2-0,96565; p=0,3258). Conclusão: A prevalência de hipotireoidismo clínico na população estudada foi maior que a determinada na população geral. Pacientes com sinais e sintomas similares tanto ao hipotireoidismo como a síndrome da apneia obstrutiva do sono podem se beneficiar da dosagem hormonal tireoidiana.

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July 2016
18 Reads

Gradual approach to refinement of the nasal tip: surgical results.

Braz J Otorhinolaryngol 2015 Jan-Feb;81(1):31-6. Epub 2014 Oct 18.

Departamento de Otorrinolaringologia e Cirurgia de Cabeça e Pescoço do Hospital de Base de São José do Rio Preto - Faculdade de Medicina de São José do Rio Preto (FAMERP), São José do Rio Preto, SP, Brazil.

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http://www.scielo.br/pdf/bjorl/v81n1/pt_1808-8694-bjorl-81-0
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http://www.redalyc.org/pdf/3924/392437932007.pdf
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http://linkinghub.elsevier.com/retrieve/pii/S180886941400131
Publisher Site
http://dx.doi.org/10.1016/j.bjorl.2014.04.003DOI Listing
May 2016
20 Reads

Molecular approach of auditory neuropathy.

Braz J Otorhinolaryngol 2015 May-Jun;81(3):321-8. Epub 2015 Mar 30.

Department of Otorhinolaryngology and Head and Neck Surgery, Faculdade de Medicina de São José do Rio Preto (FAMERP), São José do Rio Preto, SP, Brazil.

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http://dx.doi.org/10.1016/j.bjorl.2015.03.005DOI Listing
October 2015
11 Reads

Association of temporomandibular dysfunction with the 102T-C polymorphism in the serotonin receptor gene in Brazilian patients.

Arch Med Sci 2013 Dec 29;9(6):1013-8. Epub 2013 Nov 29.

Department of Otolaryngology and Head and Neck Surgery, Faculty of Medicine of São José do Rio Preto, São Paulo, Brazil (FAMERP).

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http://dx.doi.org/10.5114/aoms.2013.39215DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3902708PMC
December 2013
24 Reads
1 Citation
1.890 Impact Factor

Relationship of obstructive sleep apnea syndrome with the 5-HT2A receptor gene in Brazilian patients.

Sleep Breath 2013 Mar 27;17(1):57-62. Epub 2012 Jan 27.

Department of Otorhinolaryngology and Sleep Disorder Out Clinics, São José do Rio Preto Medical School, São Paulo, Brazil.

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http://link.springer.com/10.1007/s11325-012-0645-y
Publisher Site
http://dx.doi.org/10.1007/s11325-012-0645-yDOI Listing
March 2013
25 Reads
5 Citations
2.870 Impact Factor

Polymorphisms in the 5-HTR2A gene related to obstructive sleep apnea syndrome.

Braz J Otorhinolaryngol 2011 Jun;77(3):348-55

Otorhinolaryngology and Head & Neck Surgery Department, FAMERP.

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http://dx.doi.org/10.1590/s1808-86942011000300013DOI Listing
June 2011
17 Reads
1 Citation

Perspectives for early genetic screening of lactose intolerance: -13910C/T polymorphism tracking in the MCM6 gene.

Open Biol J. 2010;3:66-71.

Open Biol J

Abstract: Introduction: For many years Lactose intolerance has been, considered as a universal problem in many children and adults. Objective: The aim is to investigate the prevalence of polymorphism -13910C/T, in a neonatal tracking, for early diagnosis of lactose tolerance/intolerance. Materials and Methods: In a cross-sectional study of 310 Brazilian newborns, DNA was extracted from leukocyte umbilical cord and specific primers were used to amplify the region that encloses the -13910C/T polymorphism of the MCM6 gene, using the polymerase chain reaction and the restriction fragment length polymorphism tests. Results: One hundred and sixty (52%) male newborns and 150 (48%) female new borns were evaluated. Out of these, 191 (62%) presented CC genotype (lactose intolerant), 95 (31%) CT genotype, and 24 (7%) TT genotype, comprising a total of 119 (38%) lactose tolerant newborns. Accordingly the newborns´ gender distribution in relation to the phenotypes has been found; 97 (32%) of male gender and 94 (30%) of female gender lactose intolerant, and 63 (20%) male and 56 (18%) female lactose tolerant newborns, not being such distribution statistically significant (p = 0.801). Conclusions: The molecular analysis made possible the identification of the presence or absence of lactase persistence variant in the Brazilian newborns. The neonatal molecular diagnosis can optimize the follow-up of positive results in newborn screening for lactose intolerance.

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July 2010
15 Reads

Screening of the mitochondrial A1555G mutation in patients with sensorineural hearing loss.

Braz J Otorhinolaryngol 2008 Sep-Oct;74(5):731-736

Livre-docente (habilitation) professor, head of the Otorhinolaryngology and Head & Neck Surgery Department, Medical School, S. J. Rio Preto, SP, FAMERP. Medical School, São José do Rio Preto, SP, FAMERP.

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http://dx.doi.org/10.1016/S1808-8694(15)31384-7DOI Listing
August 2009
15 Reads
5 Citations

Tracking of the genetic deafness associated to the aging in Brazilian patients.

Neurobiol Aging 2009 Jul 26;30(7):1173-4. Epub 2007 Nov 26.

Medical School of São José do Rio Preto (FAMERP), Department of Otorhinolaryngology, São Paulo, Brazil.

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http://dx.doi.org/10.1016/j.neurobiolaging.2007.10.004DOI Listing
July 2009
10 Reads
5.013 Impact Factor

Correlation between audiometric data and the 35delG mutation in ten patients.

Braz J Otorhinolaryngol 2007 Nov-Dec;73(6):777-783

PhD. Head of the Center for Molecular Biology and Genetic Engineering - CBMEG-UNICAMP; Faculdade de Medicina de São José do Rio Preto, SP - FAMERP.

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http://dx.doi.org/10.1016/S1808-8694(15)31174-5DOI Listing
June 2008
93 Reads
1 Citation

Molecular genetics of non-syndromic deafness.

Braz J Otorhinolaryngol 2005 Mar-Apr;71(2):216-23. Epub 2005 Aug 2.

Department of Anatomy, Medical School, FAMERP, São José do Rio Preto, SP.

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http://dx.doi.org/10.1016/s1808-8694(15)31313-6DOI Listing
July 2006
12 Reads
5 Citations

[Prospects for genetic hearing loss screening: 35delG mutation tracking in a newborn population].

J Pediatr (Rio J) 2005 Mar-Apr;81(2):139-42

Departamento de Anatomia, Faculdade de Medicina de São José do Rio Preto (FAMERP), SP.

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December 2005
11 Reads
1 Citation
0.940 Impact Factor

Prevalence of the GJB2 mutations and the del(GJB6-D13S1830) mutation in Brazilian patients with deafness.

Hear Res 2004 Oct;196(1-2):87-93

Medical School of São José do Rio Preto, Rua Frei Baltazar, No. 415, Boa Vista, São José do Rio Preto, São Paulo 15025-390, Brazil.

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http://dx.doi.org/10.1016/j.heares.2004.05.007DOI Listing
October 2004
15 Reads
3 Citations
2.970 Impact Factor

[Hearing evaluation in children aged 3-6 years in day-care centers]

J Pediatr (Rio J) 2001 Mar-Apr;77(2):124-30

Faculdade de Medicina de São José do Rio Preto (FAMERP), São Paulo, SP, Brazil.

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http://dx.doi.org/10.2223/jped.188DOI Listing
December 2003
19 Reads
0.940 Impact Factor