Mr Afees Oladejo, B.Sc., M.Sc. - Afe Babalola University Ado Ekiti  - Mr

Mr Afees Oladejo

B.Sc., M.Sc.

Afe Babalola University Ado Ekiti

Mr

Ado Ekiti, Ekiti State | Nigeria

Main Specialties: Hematology, Medical Toxicology, Pharmacology

Additional Specialties: Medical biochemistry and toxicology


Top Author

Mr Afees Oladejo, B.Sc., M.Sc. - Afe Babalola University Ado Ekiti  - Mr

Mr Afees Oladejo

B.Sc., M.Sc.

Introduction

Afees Adebayo Oladejo (B. Sc., M.Sc.) is a researcher who is currently pursuing his PhD degree in Medical Biochemistry and Immunochemistry. He bagged his Masters degree in Medical Biochemistry and Toxicology from Afe Babalola University in October, 2017 and his B.Sc. in Biochemistry from Ekiti State University in April, 2013. His research focuses on medicinal properties and nutritive values of plant parts. He has authored research publications in numerous reputable peer reviewed journals including British Journal of Pharmaceutical Research, Journal of Applied Life Science International and Journal of Advances in Microbiology among others.

Primary Affiliation: Afe Babalola University Ado Ekiti - Ado Ekiti, Ekiti State , Nigeria

Specialties:

Additional Specialties:

Research Interests:


View Mr Afees Oladejo’s Resume / CV

Education

Oct 2017
Afe Babalola University
M.Sc
Distinction
Apr 2013
Ekiti State University
B.Sc
Hons.

Experience

Nov 2017
Certificate of Presentation. NAMS
presented a paper at the national conference
National Association of Microbiology Students
Oct 2017
Certificate of Presentation. NSBMB
presented a paper at the international conference of NSBMB
National Association of Biochemistry and Molecular Biology
Oct 2017
Certificate of Presentation. NSBMB
presented a paper at the international conference of NSBMB
National Association of Biochemistry and Molecular Biology
Aug 2006
Certificate of Participation. Chemical Society of Nigeria
Participated in national chemistry competition
Chemical Society of Nigeria

Publications

6Publications

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Evaluation of Goitrogenic Content of Common Vegetables in South West Nigeria

AFSJ. 2018 Aug 4(1): 1-6.

African food science journal

Endemic goiter and associated iodine deficiency disorders (IDD) are prevalent in south west Nigeria. The present study was undertaken to identify the role of dietary goitrogen in the etiology of endemic goiter. Perchlorate, fluoride, nitrate, bromide, chloride, phosphate and cyanide content of common vegetables viz., cabbage, African Eggplant, Giant pigweed, Scent leaf, Amaranth, Tree Spinach, Black nightshade, consumed by the population of the region were measured. All the dietary goitrogen content in the investigated vegetables were found to be within the Acceptable Daily Intake and this observation suggests that in addition to iodine deficiency dietary intake of a cyanogenic plant, the combination of chemicals may play some role for the persistence of endemic goiter in Southwest Nigeria.

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August 2018
3 Reads

Anthelmintic and antioxidant potentials of leaf fractions of Bridelia ferruginea

Int. J. of Pharm. Life Sci. 2018 April 9(4):5785-5795

INTERNATIONAL JOURNAL OF PHARMACY & LIFE SCIENCES

Bridelia ferruginea leaf generally used in indigenous folk medicine for diverse purpose was evaluated scientifically to elucidate its anthelmintic and antioxidant activity of various fractions in-vitro. Antioxidant properties of the fractions were evaluated using total phenol (mg/GAE g), total flavonoids (mg/QUEg), and ferric reducing ability (mg/g). The total antioxidant activities results indicated that, n-hexane fraction has significant higher antioxidant properties compared to other fractions (n-butanol, ethyl acetate and residual aqueous). The in vitro anthelmintic activities of the plant fractions were carried out on Pheretima posthuma, Ascaris suum and Heamonchus placei at varying concentrations of 25-100 mg/ml in three replicates. The plants’ fractions caused a dose-dependent motility inhibition with highest effect from n-hexane fraction. The results confirm that Bridelia ferruginea leaves are potential sources for novel anthelmintics and their varied degrees of antioxidant activity has the potential to be developed into dietary supplements and synergically modified with synthetic antioxidants.

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April 2018
1 Read

Comparative Proximate, Minerals and Antinutrient Analysis of Selected Nigerian Leafy Vegetables

JALSI. 2018 Jan 16(1): 1-8.

Journal of Applied Life Sciences International

Aims: To evaluate the contributions of Nigerian leafy vegetables to nutrition and health. Methodology: Eight leafy vegetables were comparatively analyzed for proximate, mineral and antinutrient compositions. Results: The proximate composition showed that the vegetables are good sources of protein, energy and fiber. Brassica oleracea has the highest protein content while Brassica oleracea and Trianthema portulacastrum are the richest in fiber. The result showed that the vegetables are good sources of iron, manganese, magnesium, potassium and calcium. Trianthema portulacastrum has the highest levels of minerals. The Recommended Dietary Allowance for manganese, magnesium and calcium can be met by a 100 g per day servings of the vegetables; while up to 60% of the Recommended Dietary Allowance for iron and potassium can be met by a 100 g per day servings of the vegetables. The vegetables were poor sources of zinc. The level of sodium in the vegetables was very low. The antinutrients in the investigated vegetables were much lower than safe limits and levels reported for other plant sourced foods including nuts, roots, beans and berries. Conclusion: The investigated vegetables are good sources of essential nutrients and are low in antinutrients.

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January 2018

Inhibitory Effects of Aqueous Extract of Bridelia ferruginea Stem Bark on Iron (II) Sulphate - Induced Oxidative Stress in Brain and Liver of Albino Wistar Rats

JALSI. 2017 14(2): 1-7.

Journal of Applied Life Sciences International

The antioxidant potential of Bridelia ferruginea, which is a widely used medicinal plant in Nigeria, sub-tropical Africa and parts of Asia was investigated using thiobarbituric acid reactive species (TBARS) assay. The aqueous extract of Bridelia ferruginea stem bark used in this study showed inhibition against the formation of thiobarbituric acid reactive species (TBARS) induced by Iron (II) sulphate in the liver and brain tissue homogenates of the locally bred male and female albino- Wistar rats used. The extract was discovered to have different antioxidant potentials in a manner that was concentration dependent. The aqueous extract of the plant showed a good percentage inhibition of 56.06% in the liver homogenate and 60.65% in the brain homogenate both at a concentration of 0.33 mg/ml using iron (II) sulphate as pro-oxidant with IC50 values of 3.00 ± 1.59mg/ml for the liver and 3.00 ± 1.60 mg/ml for the brain. The result therefore suggests the medicinal benefit of Bridelia ferruginea in the treatment of various diseases induced by oxidative stress due to its ability to act as antioxidant.

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October 2017

Phytochemical Constituents, Proximate Composition and Mineral Analysis of Aqueous and Ethanolic Stem Bark, Seed Extracts and Plant Parts of Moringa oleifera

JALSI. 2017 10(4): 1-7, 2017;

Journal of Applied Life Sciences International

Moringa oleifera is a small size multipurpose tree of approximately 5 to 10 m in height which is cultivated all over the world. The phytochemical constituents of aqueous and ethanolic stem bark and seed extracts of Moringa oleifera were assessed and compared. The mineral and proximate analyses were carried out on some selected parts of the plant. The result of the qualitative phytochemical constituents showed the presence of tannins, flavonoid, alkaloids, saponins, steroids, terpenoids and cardiac glycoside in both aqueous and ethanolic extracts. Results showed the presence of iron, calcium, potassium and zinc. Proximate analysis in all the investigated plant parts revealed the presence of carbohydrate, protein, fat, fiber and ash with the leaves having highest percentage of protein (18.61%). The results from this study prove extensively the use of the plant in ethnomedicine and its potential for diet formulation

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March 2017
1 Read

Phytochemical Screening and Antimicrobial Activity of Leaf Extract of Jatropha curcas

JAMPS. 2016 May 8(1): 1-6.

Journal of Advances in Medical and Pharmaceutical Sciences

The study investigated the antibacterial activity of Jatropha curcas using aqueous, methanol and ethanolic extracts that were obtained from the leaf against growth inhibition of Escherichia coli, Staphylococcus aureus, Proteus spp, Klebsiella pneumonia and Pseudomonas aeruginosa. Tannins, saponins, flavonoids, alkaloids, oxalates and cyanogenic glycosides were the phytochemicals present. All test microorganisms were significantly inhibited by the leaf extracts but the presence of oxalates and cyanogenic glycosides in the leaf could present potential toxicity and therefore reduces the application of this plant to topical but not systemic use. Clearly, additional pharmacology and safety studies are warranted to investigate clinical potential of Jatropha curcas as a topical antibiotic for use against susceptible pathogens.

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May 2016
1 Read