Zvi Fuks

Zvi Fuks

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Zvi Fuks

Zvi Fuks

Publications by authors named "Zvi Fuks"

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Phenotype-Oriented Ablation of Oligometastatic Cancer with Single Dose Radiation Therapy.

Int J Radiat Oncol Biol Phys 2019 07 21;104(3):593-603. Epub 2019 Feb 21.

The Champalimaud Centre for the Unknown, Lisbon, Portugal; Memorial Sloan Kettering Cancer Center, New York, New York.

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http://dx.doi.org/10.1016/j.ijrobp.2019.02.033DOI Listing
July 2019

Long-Term Implications of a Positive Posttreatment Biopsy in Patients Treated with External Beam Radiotherapy for Clinically Localized Prostate Cancer.

J Urol 2019 06;201(6):1127-1133

Departments of Radiation Oncology, Pathology and Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center , New York , New York.

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http://dx.doi.org/10.1097/JU.0000000000000110DOI Listing
June 2019

The evolving role of external beam radiotherapy in localized prostate cancer.

Semin Oncol 2019 06 22;46(3):246-253. Epub 2019 Aug 22.

The Champalimaud Centre for the Unknown, Lisbon, Portugal; Memorial Sloan Kettering Cancer Center, New York, New York.

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http://dx.doi.org/10.1053/j.seminoncol.2019.08.001DOI Listing
June 2019

Logarithmic expansion of LGR5 cells in human colorectal cancer.

Cell Signal 2018 Jan 25;42:97-105. Epub 2017 Sep 25.

Department of Surgery, Memorial Sloan-Kettering Cancer Center, New York, NY 10065, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cellsig.2017.09.018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5766032PMC
January 2018

Gemcitabine kills proliferating endothelial cells exclusively via acid sphingomyelinase activation.

Cell Signal 2017 06 24;34:86-91. Epub 2017 Feb 24.

Laboratory of Signal Transduction, Memorial Sloan-Kettering Cancer Center, New York, NY 10065, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cellsig.2017.02.021DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5565230PMC
June 2017

Spinal metastases: From conventional fractionated radiotherapy to single-dose SBRT.

Rep Pract Oncol Radiother 2015 Nov-Dec;20(6):454-63. Epub 2015 Apr 18.

Radiation Oncology, Champalimaud Centre for the Unknown, Lisbon, Portugal.

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http://dx.doi.org/10.1016/j.rpor.2015.03.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4661345PMC
December 2015

Axitinib sensitization of high Single Dose Radiotherapy.

Radiother Oncol 2014 Apr 29;111(1):88-93. Epub 2014 Apr 29.

Laboratory of Signal Transduction, Memorial Sloan-Kettering Cancer Center, New York, USA.

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http://dx.doi.org/10.1016/j.radonc.2014.02.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4278650PMC
April 2014

Crypt base columnar stem cells in small intestines of mice are radioresistant.

Gastroenterology 2012 Nov 27;143(5):1266-1276. Epub 2012 Jul 27.

Laboratory of Signal Transduction, Memorial Sloan-Kettering Cancer Center, New York, New York. Electronic address:

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http://dx.doi.org/10.1053/j.gastro.2012.07.106DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3480544PMC
November 2012

Anti-ceramide antibody prevents the radiation gastrointestinal syndrome in mice.

J Clin Invest 2012 May 2;122(5):1786-90. Epub 2012 Apr 2.

Laboratory of Signal Transduction, Memorial Sloan-Kettering Cancer Center (MSKCC), New York, New York, USA.

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http://dx.doi.org/10.1172/JCI59920DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3336980PMC
May 2012

Predictors of local control after single-dose stereotactic image-guided intensity-modulated radiotherapy for extracranial metastases.

Int J Radiat Oncol Biol Phys 2011 Mar 25;79(4):1151-7. Epub 2010 May 25.

Department of Radiation Oncology, Memorial Sloan-Kettering Cancer Center, New York, NY 10065, USA.

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http://dx.doi.org/10.1016/j.ijrobp.2009.12.038DOI Listing
March 2011

Impact of stromal sensitivity on radiation response of tumors implanted in SCID hosts revisited.

Cancer Res 2010 Oct 5;70(20):8179-86. Epub 2010 Oct 5.

Laboratory of Signal Transduction and Department of Radiation Oncology, Memorial Sloan-Kettering Cancer Center; Department of Pathology, Columbia University, New York, NY 10065, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-10-1871DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2976483PMC
October 2010

Ceramide synthases 2, 5, and 6 confer distinct roles in radiation-induced apoptosis in HeLa cells.

Cell Signal 2010 Sep 18;22(9):1300-7. Epub 2010 Apr 18.

Laboratory of Signal Transduction, Memorial Sloan-Kettering Cancer Center, 1275 York Avenue, New York, NY 10021, USA.

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http://dx.doi.org/10.1016/j.cellsig.2010.04.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4348005PMC
September 2010

Regulation of ceramide synthase-mediated crypt epithelium apoptosis by DNA damage repair enzymes.

Cancer Res 2010 Feb 19;70(3):957-67. Epub 2010 Jan 19.

Laboratory of Signal Transduction, Memorial Sloan-Kettering Cancer Center, New York, New York 10021, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-09-1562DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4440583PMC
February 2010

Kinase suppressor of Ras transphosphorylates c-Raf-1.

Biochem Biophys Res Commun 2009 Dec 17;390(3):434-40. Epub 2009 Sep 17.

Laboratory of Signal Transduction, Memorial Sloan-Kettering Cancer Center, 1275 York Avenue, New York, NY 10065, USA.

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http://dx.doi.org/10.1016/j.bbrc.2009.09.048DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2800940PMC
December 2009

A ceramide-binding C1 domain mediates kinase suppressor of ras membrane translocation.

Cell Physiol Biochem 2009 3;24(3-4):219-30. Epub 2009 Aug 3.

Laboratory of Signal Transduction, Department of Radiation Oncology, Memorial Sloan-Kettering Cancer Center, New York, NY 10021, USA.

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http://dx.doi.org/10.1159/000233248DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2978518PMC
November 2009

Timing of lethality from gastrointestinal syndrome in mice revisited.

Int J Radiat Oncol Biol Phys 2009 Jan;73(1):6-8

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http://dx.doi.org/10.1016/j.ijrobp.2008.09.009DOI Listing
January 2009

Ceramide biogenesis is required for radiation-induced apoptosis in the germ line of C. elegans.

Science 2008 Oct;322(5898):110-5

Laboratory of Signal Transduction, Memorial Sloan-Kettering Cancer Center (MSKCC), New York, NY 10021, USA.

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http://dx.doi.org/10.1126/science.1158111DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2585063PMC
October 2008

Downregulation of KSR1 in pancreatic cancer xenografts by antisense oligonucleotide correlates with tumor drug uptake.

Cancer Biol Ther 2008 Sep 15;7(9):1490-5. Epub 2008 Sep 15.

Laboratory of Signal Transduction, Memorial Sloan-Kettering Cancer Center, New York, New York 10065, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2576298PMC
http://dx.doi.org/10.4161/cbt.7.9.6472DOI Listing
September 2008

Comparison of kilovoltage cone-beam computed tomography with megavoltage projection pairs for paraspinal radiosurgery patient alignment and position verification.

Int J Radiat Oncol Biol Phys 2008 Aug 6;71(5):1572-80. Epub 2008 Jun 6.

Department of Medical Physics, Memorial Sloan-Kettering Cancer Center, 1275 York Avenue, New York, NY 10021, USA.

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http://dx.doi.org/10.1016/j.ijrobp.2008.04.029DOI Listing
August 2008

Long-term results of conformal radiotherapy for prostate cancer: impact of dose escalation on biochemical tumor control and distant metastases-free survival outcomes.

Int J Radiat Oncol Biol Phys 2008 Jul 14;71(4):1028-33. Epub 2008 Feb 14.

Department of Radiation Oncology, Memorial Sloan-Kettering Cancer Center, New York, NY 10065, USA.

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http://dx.doi.org/10.1016/j.ijrobp.2007.11.066DOI Listing
July 2008

Ultra-high dose (86.4 Gy) IMRT for localized prostate cancer: toxicity and biochemical outcomes.

Int J Radiat Oncol Biol Phys 2008 Jun 31;71(2):330-7. Epub 2007 Dec 31.

Department of Radiation Oncology, Memorial Sloan-Kettering Cancer Center, New York, NY, USA.

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http://dx.doi.org/10.1016/j.ijrobp.2007.10.004DOI Listing
June 2008

High-dose, single-fraction image-guided intensity-modulated radiotherapy for metastatic spinal lesions.

Int J Radiat Oncol Biol Phys 2008 Jun 30;71(2):484-90. Epub 2008 Jan 30.

Department of Radiation Oncology, Memorial Sloan-Kettering Cancer Center, New York, NY 10021, USA.

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http://dx.doi.org/10.1016/j.ijrobp.2007.11.046DOI Listing
June 2008

Influence of local tumor control on distant metastases and cancer related mortality after external beam radiotherapy for prostate cancer.

J Urol 2008 Apr 4;179(4):1368-73; discussion 1373. Epub 2008 Mar 4.

Department of Radiation Oncology, Memorial Sloan-Kettering Cancer Center, New York, New York, USA.

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http://dx.doi.org/10.1016/j.juro.2007.11.063DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2646887PMC
April 2008

Bax and Bak do not exhibit functional redundancy in mediating radiation-induced endothelial apoptosis in the intestinal mucosa.

Int J Radiat Oncol Biol Phys 2008 Mar 11;70(3):804-15. Epub 2008 Jan 11.

Laboratory of Signal Transduction, Memorial Sloan-Kettering Cancer Center, New York, NY 10021, USA.

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http://dx.doi.org/10.1016/j.ijrobp.2007.11.043DOI Listing
March 2008

Kinetic characterization of mammalian ceramide synthases: determination of K(m) values towards sphinganine.

FEBS Lett 2007 Nov 23;581(27):5289-94. Epub 2007 Oct 23.

Department of Biological Chemistry, Weizmann Institute of Science, Rehovot 76100, Israel.

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http://dx.doi.org/10.1016/j.febslet.2007.10.018DOI Listing
November 2007

A CERTain role for ceramide in taxane-induced cell death.

Cancer Cell 2007 Jun;11(6):473-5

Program of Molecular Pharmacology and Chemistry, Memorial Sloan-Kettering Cancer Center, 1275 York Avenue, New York, NY 10021, USA.

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http://linkinghub.elsevier.com/retrieve/pii/S153561080700147
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http://dx.doi.org/10.1016/j.ccr.2007.05.003DOI Listing
June 2007

From IMRT to IGRT: frontierland or neverland?

Radiother Oncol 2006 Feb 18;78(2):119-22. Epub 2006 Jan 18.

Department of Medical Physics, Memorial Sloan Kettering Cancer Center, New York, NY, USA.

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http://dx.doi.org/10.1016/j.radonc.2005.12.005DOI Listing
February 2006

Image-fusion of MR spectroscopic images for treatment planning of gliomas.

Med Phys 2006 Jan;33(1):32-40

Department of Medical Physics, Memorial Sloan-Kettering Cancer Center, 1275 York Avenue, New York, New York 10021, USA.

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http://dx.doi.org/10.1118/1.2128497DOI Listing
January 2006

Whole pelvic radiotherapy for prostate cancer using 3D conformal and intensity-modulated radiotherapy.

Int J Radiat Oncol Biol Phys 2005 Nov;63(3):765-71

Department of Radiation Oncology, Memorial Sloan-Kettering Cancer Center, New York, NY 10021, USA.

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http://dx.doi.org/10.1016/j.ijrobp.2005.02.050DOI Listing
November 2005

Engaging the vascular component of the tumor response.

Cancer Cell 2005 Aug;8(2):89-91

Department of Radiation Oncology, Memorial Sloan-Kettering Cancer Center, 1275 York Avenue, New York, New York 10021, USA.

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http://linkinghub.elsevier.com/retrieve/pii/S153561080500235
Publisher Site
http://dx.doi.org/10.1016/j.ccr.2005.07.014DOI Listing
August 2005

Accurate setup of paraspinal patients using a noninvasive patient immobilization cradle and portal imaging.

Med Phys 2005 Aug;32(8):2606-14

Department of Medical Physics, Memorial Sloan-Kettering Cancer Center, New York, New York 10021, USA.

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http://dx.doi.org/10.1118/1.1951042DOI Listing
August 2005

Caspase-dependent and -independent activation of acid sphingomyelinase signaling.

J Biol Chem 2005 Jul 22;280(28):26425-34. Epub 2005 Apr 22.

Laboratory of Signal Transduction and Department of Radiation Oncology, Memorial Sloan-Kettering Cancer Center, New York, New York 10021, USA.

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http://dx.doi.org/10.1074/jbc.M414569200DOI Listing
July 2005

Down-regulation of ATM protein sensitizes human prostate cancer cells to radiation-induced apoptosis.

J Biol Chem 2005 Jun 18;280(24):23262-72. Epub 2005 Apr 18.

Department of Radiation Oncology, Memorial Sloan-Kettering Cancer Center, New York, New York 10021, USA.

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http://dx.doi.org/10.1074/jbc.M503701200DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1855286PMC
June 2005

ATM regulates target switching to escalating doses of radiation in the intestines.

Nat Med 2005 May 1;11(5):484-90. Epub 2005 May 1.

Department of Radiation Oncology, Memorial Sloan-Kettering Cancer Center, 1275 York Avenue, New York, New York 10021, USA.

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http://dx.doi.org/10.1038/nm1237DOI Listing
May 2005

Outcome predictors for the increasing PSA state after definitive external-beam radiotherapy for prostate cancer.

J Clin Oncol 2005 Feb;23(4):826-31

Department of Radiation Oncology, Memorial Sloan-Kettering Cancer Center, 1275 York Avenue, New York, NY 10021, USA.

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http://dx.doi.org/10.1200/JCO.2005.02.111DOI Listing
February 2005

Host acid sphingomyelinase regulates microvascular function not tumor immunity.

Cancer Res 2004 Nov;64(22):8285-91

Laboratory of Signal Transduction, Memorial Sloan-Kettering Cancer Center, New York, New York 10021, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-04-2715DOI Listing
November 2004

Advances in translational radiation oncology: from molecular signaling to cancer cure.

Int J Radiat Oncol Biol Phys 2004 Feb;58(2):305-6

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http://dx.doi.org/10.1016/j.ijrobp.2003.09.055DOI Listing
February 2004

Improved biochemical disease-free survival of men younger than 60 years with prostate cancer treated with high dose conformal external beam radiotherapy.

J Urol 2003 Nov;170(5):1828-32

Department of Radiation Oncology, Memorial Sloan-Kettering Cancer Center, 1275 York Avenue, New York, NY 10021, USA.

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http://dx.doi.org/10.1097/01.ju.0000093720.46502.24DOI Listing
November 2003

Pharmacologic inactivation of kinase suppressor of ras-1 abrogates Ras-mediated pancreatic cancer.

Nat Med 2003 Oct 7;9(10):1266-8. Epub 2003 Sep 7.

Laboratory of Signal Transduction, Memorial Sloan-Kettering Cancer Center, 1275 York Avenue, New York, New York 10021, USA.

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http://dx.doi.org/10.1038/nm927DOI Listing
October 2003

Technological advances in external-beam radiation therapy for the treatment of localized prostate cancer.

Semin Oncol 2003 Oct;30(5):596-615

Department of Radiation Oncology, Memorial Sloan-Kettering Cancer Center, New York, NY 10021, USA.

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http://dx.doi.org/10.1016/s0093-7754(03)00354-3DOI Listing
October 2003

Radiation and ceramide-induced apoptosis.

Oncogene 2003 Sep;22(37):5897-906

Laboratory of Signal Transduction, Department of Radiation Oncology, Memorial Sloan-Kettering Cancer Center, 1275 York Avenue, New York, NY 10021, USA.

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http://dx.doi.org/10.1038/sj.onc.1206702DOI Listing
September 2003

Microvascular function regulates intestinal crypt response to radiation.

Cancer Res 2003 Aug;63(15):4338-41

Laboratory of Signal Transduction, Department of Radiation Oncology, Memorial Sloan-Kettering Cancer Center, 1275 York Avenue, New York, NY 10021.

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August 2003

Tumor response to radiotherapy regulated by endothelial cell apoptosis.

Science 2003 May;300(5622):1155-9

Laboratory of Signal Transduction, Memorial Sloan-Kettering Cancer Center, 1275 York Avenue, New York, NY 10021, USA.

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http://dx.doi.org/10.1126/science.1082504DOI Listing
May 2003

A study of the effects of internal organ motion on dose escalation in conformal prostate treatments.

Radiother Oncol 2003 Mar;66(3):263-70

Department of Medical Physics, Memorial Sloan-Kettering Cancer Center, 1275 York Avenue, New York, NY 10021, USA.

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http://dx.doi.org/10.1016/s0167-8140(03)00039-2DOI Listing
March 2003

Predictors of biochemical outcome with salvage conformal radiotherapy after radical prostatectomy for prostate cancer.

J Clin Oncol 2003 Feb;21(3):483-9

Departments of Radiation Oncology and Biostatistics, Memorial Sloan-Kettering Cancer Center, New York, NY 10021, USA.

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http://dx.doi.org/10.1200/JCO.2003.12.043DOI Listing
February 2003

IMRT of large fields: whole-abdomen irradiation.

Int J Radiat Oncol Biol Phys 2002 Sep;54(1):278-89

Department of Medical Physics, Memorial Sloan-Kettering Cancer Center, 1275 York Avenue, New York, NY 10021, USA.

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http://dx.doi.org/10.1016/s0360-3016(02)02921-8DOI Listing
September 2002

High-dose intensity modulated radiation therapy for prostate cancer: early toxicity and biochemical outcome in 772 patients.

Int J Radiat Oncol Biol Phys 2002 Aug;53(5):1111-6

Department of Radiation Oncology, Memorial Sloan-Kettering Cancer Center, New York, NY 10021, USA.

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http://dx.doi.org/10.1016/s0360-3016(02)02857-2DOI Listing
August 2002

Intensity-modulated radiation therapy for prostate cancer.

Semin Radiat Oncol 2002 Jul;12(3):229-37

Department of Radiation Oncology, Memorial Sloan-Kettering Cancer Center, New York, NY 10021, USA.

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http://dx.doi.org/10.1053/srao.2002.00000DOI Listing
July 2002

Involvement of membrane signaling in the bystander effect in irradiated cells.

Cancer Res 2002 May;62(9):2531-4

Laboratory of Radiobiology, Harvard School of Public Health, Boston, Massachusetts 02115, USA.

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May 2002

Normalization of serum testosterone levels in patients treated with neoadjuvant hormonal therapy and three-dimensional conformal radiotherapy for prostate cancer.

Int J Radiat Oncol Biol Phys 2002 Feb;52(2):439-43

Department of Radiation Oncology, Memorial Sloan-Kettering Cancer Center, New York, NY 10021, USA.

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http://dx.doi.org/10.1016/s0360-3016(01)02604-9DOI Listing
February 2002