Zuoming Sun

Zuoming Sun

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Zuoming Sun

Publications by authors named "Zuoming Sun"

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Effects of Microvesicles on Cell Apoptosis under Hypoxia.

Oxid Med Cell Longev 2019 17;2019:5972152. Epub 2019 Apr 17.

Department of Geriatrics, Tianjin Medical University General Hospital, Tianjin Geriatrics Institute, Tianjin, China.

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http://dx.doi.org/10.1155/2019/5972152DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6501227PMC
January 2020

4-phenylbutyric acid attenuates endoplasmic reticulum stress-mediated apoptosis and protects the hepatocytes from intermittent hypoxia-induced injury.

Sleep Breath 2019 Jun 15;23(2):711-717. Epub 2018 Oct 15.

Geriatrics, Institute of Gerontology of Tianjin, Tianjin Medical University General Hospital, No.154, Anshan Road, Heping District, Tianjin, China.

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http://link.springer.com/10.1007/s11325-018-1739-y
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http://dx.doi.org/10.1007/s11325-018-1739-yDOI Listing
June 2019

SRC3 Is a Cofactor for RORγt in Th17 Differentiation but Not Thymocyte Development.

J Immunol 2019 02 19;202(3):760-769. Epub 2018 Dec 19.

Department of Molecular Immunology, Beckman Research Institute of City of Hope, Duarte, CA 91010;

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http://dx.doi.org/10.4049/jimmunol.1801187DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6344289PMC
February 2019

Intermittent-Hypoxia-Induced Autophagy Activation Through the ER-Stress-Related PERK/eIF2α/ATF4 Pathway is a Protective Response to Pancreatic β-Cell Apoptosis.

Cell Physiol Biochem 2018 14;51(6):2955-2971. Epub 2018 Dec 14.

Department of Geriatrics, Tianjin Medical University General Hospital, Tianjin Geriatrics Institute, Tianjin,

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http://dx.doi.org/10.1159/000496047DOI Listing
January 2019

Sumoylation of RORγt regulates T17 differentiation and thymocyte development.

Nat Commun 2018 11 19;9(1):4870. Epub 2018 Nov 19.

Division of Molecular Immunology, Beckman Research Institute of City of Hope, Duarte, 91010, CA, USA.

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http://www.nature.com/articles/s41467-018-07203-z
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http://dx.doi.org/10.1038/s41467-018-07203-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6242824PMC
November 2018

CRACR2A-Mediated TCR Signaling Promotes Local Effector Th1 and Th17 Responses.

J Immunol 2018 08 9;201(4):1174-1185. Epub 2018 Jul 9.

Department of Physiology, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA 90095;

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http://dx.doi.org/10.4049/jimmunol.1800659DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6081249PMC
August 2018

PRMT1 Plays a Critical Role in Th17 Differentiation by Regulating Reciprocal Recruitment of STAT3 and STAT5.

J Immunol 2018 07 23;201(2):440-450. Epub 2018 May 23.

Division of Immunology, Beckman Research Institute of City of Hope, Duarte, CA 91010;

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http://dx.doi.org/10.4049/jimmunol.1701654DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6039255PMC
July 2018

TCF-1 Inhibits IL-17 Gene Expression To Restrain Th17 Immunity in a Stage-Specific Manner.

J Immunol 2018 05 9;200(10):3397-3406. Epub 2018 Apr 9.

Department of Molecular Immunology, Beckman Research Institute of the City of Hope, Duarte, CA 91010;

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http://dx.doi.org/10.4049/jimmunol.1800193DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5940498PMC
May 2018

SRC1 promotes Th17 differentiation by overriding Foxp3 suppression to stimulate RORγt activity in a PKC-θ-dependent manner.

Proc Natl Acad Sci U S A 2018 01 27;115(3):E458-E467. Epub 2017 Dec 27.

Division of Immunology, Beckman Research Institute of the City of Hope, Duarte, CA 91010;

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http://www.pnas.org/lookup/doi/10.1073/pnas.1717789115
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http://dx.doi.org/10.1073/pnas.1717789115DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5776998PMC
January 2018

Immunological Disorders: Regulation of Ca Signaling in T Lymphocytes.

Adv Exp Med Biol 2017 ;993:397-424

Department of Physiology, David Geffen School of Medicine at UCLA, 53-266 CHS, 10833 Le Conte Avenue, Los Angeles, CA, 90095, USA.

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http://dx.doi.org/10.1007/978-3-319-57732-6_21DOI Listing
December 2017

A two-amino-acid substitution in the transcription factor RORγt disrupts its function in T17 differentiation but not in thymocyte development.

Nat Immunol 2017 Oct 28;18(10):1128-1138. Epub 2017 Aug 28.

Division of Molecular Immunology, Beckman Research Institute of City of Hope, Duarte, California, USA.

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http://dx.doi.org/10.1038/ni.3832DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5678981PMC
October 2017

Regulation of Th17 Differentiation by IKKα-Dependent and -Independent Phosphorylation of RORγt.

J Immunol 2017 08 30;199(3):955-964. Epub 2017 Jun 30.

Department of Molecular Immunology, Beckman Research Institute, City of Hope, Duarte, CA 91010;

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http://dx.doi.org/10.4049/jimmunol.1700457DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5531059PMC
August 2017

Ubiquitination of RORγt at Lysine 446 Limits Th17 Differentiation by Controlling Coactivator Recruitment.

J Immunol 2016 08 18;197(4):1148-58. Epub 2016 Jul 18.

Department of Molecular Immunology, Beckman Research Institute of the City of Hope, Duarte, CA 91010;

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http://dx.doi.org/10.4049/jimmunol.1600548DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4976012PMC
August 2016

Canonical wnt signaling in dendritic cells regulates Th1/Th17 responses and suppresses autoimmune neuroinflammation.

J Immunol 2015 Apr 20;194(7):3295-304. Epub 2015 Feb 20.

Cancer Immunology, Inflammation, and Tolerance Program, Georgia Regents University Cancer Center, Georgia Regents University, Augusta, GA 30912; Department of Medicine, Medical College of Georgia, Georgia Regents University, Augusta, GA 30912;

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http://dx.doi.org/10.4049/jimmunol.1402691DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4369436PMC
April 2015

TLR2-dependent activation of β-catenin pathway in dendritic cells induces regulatory responses and attenuates autoimmune inflammation.

J Immunol 2014 Oct 10;193(8):4203-13. Epub 2014 Sep 10.

Cancer Immunology, Inflammation, and Tolerance Program, Georgia Regents University Cancer Center, Medical College of Georgia, Georgia Regents University, Augusta, GA 30912; Department of Medicine, Medical College of Georgia, Georgia Regents University, Augusta, GA 30912; and

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http://dx.doi.org/10.4049/jimmunol.1400614DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4185231PMC
October 2014

Simultaneous quantification of 22R and 22S epimers of budesonide in human plasma by ultra-high-performance liquid chromatography-tandem mass spectrometry: application in a stereoselective pharmacokinetic study.

J Chromatogr B Analyt Technol Biomed Life Sci 2013 Mar 28;921-922:27-34. Epub 2013 Jan 28.

Zhejiang University of Technology, Hangzhou 310014, PR China.

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http://dx.doi.org/10.1016/j.jchromb.2013.01.015DOI Listing
March 2013

β-catenin/TCF-1 pathway in T cell development and differentiation.

J Neuroimmune Pharmacol 2012 Dec 27;7(4):750-62. Epub 2012 Apr 27.

Division of Immunology, Beckman Research Institute of City of Hope, Duarte, CA 91010, USA.

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http://dx.doi.org/10.1007/s11481-012-9367-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3582214PMC
December 2012

Intervention of PKC-θ as an immunosuppressive regimen.

Authors:
Zuoming Sun

Front Immunol 2012 2;3:225. Epub 2012 Aug 2.

Division of Immunology, Beckman Research Institute of the City of Hope, Duarte, CA, USA.

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http://dx.doi.org/10.3389/fimmu.2012.00225DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3410430PMC
August 2012

Ameliorated ConA-induced hepatitis in the absence of PKC-theta.

PLoS One 2012 7;7(2):e31174. Epub 2012 Feb 7.

Division of Immunology, Beckman Research Institute of the City of Hope, Duarte, California, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0031174PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3274545PMC
July 2012

Protein kinase C-θ inhibits inducible regulatory T cell differentiation via an AKT-Foxo1/3a-dependent pathway.

J Immunol 2012 Jun 25;188(11):5337-47. Epub 2012 Apr 25.

Division of Immunology, Beckman Research Institute of City of Hope, Duarte, CA 91010, USA.

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http://dx.doi.org/10.4049/jimmunol.1102979DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3484896PMC
June 2012

Protein kinase C-θ promotes Th17 differentiation via upregulation of Stat3.

J Immunol 2012 Jun 14;188(12):5887-97. Epub 2012 May 14.

Division of Immunology, Beckman Research Institute of the City of Hope, Duarte, CA 91010, USA.

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http://dx.doi.org/10.4049/jimmunol.1102941DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3484892PMC
June 2012

Developing and activated T cell survival depends on differential signaling pathways to regulate anti-apoptotic Bcl-x(L).

Clin Dev Immunol 2012 26;2012:632837. Epub 2011 Dec 26.

Division of Immunology, Beckman Research Institute of the City of Hope, 1500 East Duarte Road, Duarte, CA 91010, USA.

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http://www.hindawi.com/journals/jir/2012/632837/
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http://dx.doi.org/10.1155/2012/632837DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3253460PMC
May 2012

Transcription factor network regulating CD(+)CD8(+) thymocyte survival.

Crit Rev Immunol 2011 ;31(6):447-58

Division of Immunology, Beckman Research Institute of the City of Hope, Duarte, CA 91010, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3281554PMC
http://dx.doi.org/10.1615/critrevimmunol.v31.i6.10DOI Listing
April 2012

Development and validation of a sensitive LC-MS/MS assay for simultaneous quantitation of ranolazine and its three metabolites in human plasma.

J Chromatogr B Analyt Technol Biomed Life Sci 2012 Mar 3;889-890:10-6. Epub 2012 Feb 3.

School of Pharmacy, Yantai University, Yantai, PR China.

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http://dx.doi.org/10.1016/j.jchromb.2012.01.003DOI Listing
March 2012

Critical role of TCF-1 in repression of the IL-17 gene.

PLoS One 2011 14;6(9):e24768. Epub 2011 Sep 14.

Division of Immunology, Beckman Research Institute of the City of Hope, Duarte, California, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0024768PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3173465PMC
February 2012

T cell factor 1 regulates thymocyte survival via a RORγt-dependent pathway.

J Immunol 2011 Dec 28;187(11):5964-73. Epub 2011 Oct 28.

Division of Immunology, Beckman Research Institute, City of Hope, Duarte, CA 91010, USA.

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http://dx.doi.org/10.4049/jimmunol.1101205DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3221934PMC
December 2011

PKC-θ is a drug target for prevention of T cell-mediated autoimmunity and allograft rejection.

Endocr Metab Immune Disord Drug Targets 2010 Dec;10(4):367-72

Beckman Research Institute of the City of Hope, Duarte, CA 91010, Los Angeles, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3517208PMC
http://dx.doi.org/10.2174/1871530311006040367DOI Listing
December 2010

Deficiency of protein kinase C-theta facilitates tolerance induction.

Transplantation 2009 Feb;87(4):507-16

Department of Surgery, Division of Hepatobiliary Surgery and Liver Transplantation, Vanderbilt University Medical Center, Nashville, TN, USA.

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http://dx.doi.org/10.1097/TP.0b013e318195fd36DOI Listing
February 2009

Differential requirement of PKC-theta in the development and function of natural regulatory T cells.

Mol Immunol 2008 Dec 8;46(2):213-24. Epub 2008 Oct 8.

Department of Microbiology & Immunology, School of Medicine, University of Illinois, Chicago, IL 60612, USA.

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http://dx.doi.org/10.1016/j.molimm.2008.08.275DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2700121PMC
December 2008

Regulation of thymocyte survival by transcriptional coactivators.

Crit Rev Immunol 2006 ;26(6):475-86

Department of Microbiology & Immunology, College of Medicine, University of Illinois, Chicago, IL 60612, USA.

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http://dx.doi.org/10.1615/critrevimmunol.v26.i6.10DOI Listing
August 2008

Mechanisms regulating the development and function of natural regulatory T cells.

Arch Immunol Ther Exp (Warsz) 2008 Mar-Apr;56(2):85-102. Epub 2008 Mar 31.

Department of Microbiology and Immunology, School of Medicine, University of Illinois, Chicago, IL 60612, USA.

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http://dx.doi.org/10.1007/s00005-008-0015-4DOI Listing
May 2008

Stabilized beta-catenin potentiates Fas-mediated T cell apoptosis.

J Immunol 2008 May;180(10):6586-92

Department of Microbiology and Immunology, College of Medicine, University of Illinois, Chicago, IL 60612, USA.

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http://dx.doi.org/10.4049/jimmunol.180.10.6586DOI Listing
May 2008

T-cell receptor-induced NF-kappaB activation is negatively regulated by E3 ubiquitin ligase Cbl-b.

Mol Cell Biol 2008 Apr 28;28(7):2470-80. Epub 2008 Jan 28.

Section of Nephrology, Department of Medicine, The University of Chicago, 5841 S. Maryland Ave., MC 5100, Suite S-521, Chicago, IL 60637, USA.

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http://dx.doi.org/10.1128/MCB.01505-07DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2268433PMC
April 2008

Requirement of calcineurin a beta for the survival of naive T cells.

J Immunol 2008 Jan;180(1):106-12

Division of Immunology, Beckman Research Institute of the City of Hope, Duarte, CA 91010, USA.

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http://dx.doi.org/10.4049/jimmunol.180.1.106DOI Listing
January 2008

Retinoid-related orphan receptor gamma t is a potential therapeutic target for controlling inflammatory autoimmunity.

Expert Opin Ther Targets 2007 Jun;11(6):737-43

Medical School of the University of Illinois, Department of Microbiology & Immunology, Chicago, IL 60612, USA.

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http://dx.doi.org/10.1517/14728222.11.6.737DOI Listing
June 2007

The critical role of protein kinase C-theta in Fas/Fas ligand-mediated apoptosis.

J Immunol 2007 Jan;178(1):312-9

Department of Microbiology and Immunology, School of Medicine, University of Illinois, Chicago, IL 60612, USA.

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http://dx.doi.org/10.4049/jimmunol.178.1.312DOI Listing
January 2007

Selective function of PKC-theta in T cells.

Cell Mol Immunol 2006 Aug;3(4):263-70

Department of Microbiology and Immunology, School of Medicine, University of Illinois, Chicago, IL 60612, USA.

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August 2006

Protein kinase C-theta-mediated signals enhance CD4+ T cell survival by up-regulating Bcl-xL.

J Immunol 2006 Jun;176(11):6709-16

Department of Microbiology and Immunology, College of Medicine, University of Illinois, Chicago, IL 60612, USA.

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http://dx.doi.org/10.4049/jimmunol.176.11.6709DOI Listing
June 2006

Transcriptional regulation of CD4 gene expression by T cell factor-1/beta-catenin pathway.

J Immunol 2006 Apr;176(8):4880-7

Department of Microbiology & Immunology, College of Medicine, University of Illinois, Chicago, IL 60612, USA.

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http://dx.doi.org/10.4049/jimmunol.176.8.4880DOI Listing
April 2006

Differential roles of PKC-theta in the regulation of intracellular calcium concentration in primary T cells.

J Mol Biol 2006 Jan 8;355(3):347-59. Epub 2005 Nov 8.

Department of Microbiology and Immunology, College of Medicine, University of Illinois, Chicago, IL 60612, USA.

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http://dx.doi.org/10.1016/j.jmb.2005.10.043DOI Listing
January 2006

Stabilized beta-catenin extends thymocyte survival by up-regulating Bcl-xL.

J Immunol 2005 Dec;175(12):7981-8

Department of Microbiology and Immunology, College of Medicine, University of Illinois, Chicago, IL 60612, USA.

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http://dx.doi.org/10.4049/jimmunol.175.12.7981DOI Listing
December 2005

RORgammat recruits steroid receptor coactivators to ensure thymocyte survival.

J Immunol 2005 Sep;175(6):3800-9

Department of Microbiology and Immunology, College of Medicine, University of Illinois, Chicago, IL 60612, USA.

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http://dx.doi.org/10.4049/jimmunol.175.6.3800DOI Listing
September 2005

Regulation of the TCRalpha repertoire by the survival window of CD4(+)CD8(+) thymocytes.

Nat Immunol 2002 May 22;3(5):469-76. Epub 2002 Apr 22.

Department of Immunology, Duke University Medical Center, Durham, NC 27710, USA.

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http://dx.doi.org/10.1038/ni791DOI Listing
May 2002