Publications Authored by Zouhair Aherrahrou

Short-term high-fat diet feeding protects from the development of experimental allergic asthma in mice.

Authors:

Torsten Schröder Anna V Wiese Fanny Ender Katharina M Quell Tillman Vollbrandt Jannis Duhn Annika Sünderhauf Axel Künstner Maria E Moreno-Fernandez Stefanie Derer Zouhair Aherrahrou Ian Lewkowich Senad Divanovic Christian Sina Jörg Köhl Yves Laumonnier

Clin Exp Allergy 2019 Sep 13;49(9):1245-1257. Epub 2019 Aug 13.

Institute for Systemic Inflammation Research, University of Lübeck, Lübeck, Germany.

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http://dx.doi.org/10.1111/cea.13454	DOI Listing

September 2019

Apolipoprotein A-I Mimetic Peptide L-4F Removes Bruch's Membrane Lipids in Aged Nonhuman Primates.

Authors:

Martin Rudolf Christine A Curcio Ursula Schlötzer-Schrehardt Armin Mir Mohi Sefat Aysegül Tura Zouhair Aherrahrou Max Brinkmann Salvatore Grisanti Yoko Miura Mahdy Ranjbar

Invest Ophthalmol Vis Sci 2019 02;60(2):461-472

Department of Ophthalmology, University of Lübeck, Lübeck, Germany.

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http://dx.doi.org/10.1167/iovs.18-25786	DOI Listing

February 2019

A familial congenital heart disease with a possible multigenic origin involving a mutation in BMPR1A.

Authors:

Till Joscha Demal Melina Heise Benedikt Reiz Deepika Dogra Ingrid Brænne Hermann Reichenspurner Jörg Männer Zouhair Aherrahrou Heribert Schunkert Jeanette Erdmann Salim Abdelilah-Seyfried

Sci Rep 2019 Feb 27;9(1):2959. Epub 2019 Feb 27.

Institute of Molecular Biology, Hannover Medical School, D-30625, Hannover, Germany.

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http://dx.doi.org/10.1038/s41598-019-39648-7	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6393482	PMC

February 2019

Differentiation of human iPSCs into VSMCs and generation of VSMC-derived calcifying vascular cells.

Authors:

Anja Trillhaase Undine Haferkamp Alexandra Rangnau Marlon Märtens Beatrice Schmidt Michaela Trilck Philip Seibler Redouane Aherrahrou Jeanette Erdmann Zouhair Aherrahrou

Stem Cell Res 2018 08 17;31:62-70. Epub 2018 Jul 17.

Institute for Cardiogenetics, University of Luebeck, Germany; DZHK (German Centre for Cardiovascular Research), Partner Site Hamburg/Kiel/Luebeck, Germany; University Heart Centre Luebeck, 23562 Luebeck, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.scr.2018.07.008	DOI Listing

August 2018

Etidronate prevents dystrophic cardiac calcification by inhibiting macrophage aggregation.

Authors:

Carolin Bauer Olivier le Saux Viola Pomozi Redouane Aherrahrou Rene Kriesen Stephanie Stölting Annett Liebers Thorsten Kessler Heribert Schunkert Jeanette Erdmann Zouhair Aherrahrou

Sci Rep 2018 04 11;8(1):5812. Epub 2018 Apr 11.

Institute for Cardiogenetics, Universität zu Lübeck; DZHK (German Centre for Cardiovascular Research), Partner Site Hamburg/Kiel/Lübeck, Germany, University Heart Centre Lübeck, 23562, Lübeck, Germany.

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http://dx.doi.org/10.1038/s41598-018-24228-y	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5895639	PMC

April 2018

Compartment-resolved Proteomic Analysis of Mouse Aorta during Atherosclerotic Plaque Formation Reveals Osteoclast-specific Protein Expression.

Authors:

Michael Wierer Matthias Prestel Herbert B Schiller Guangyao Yan Christoph Schaab Sepiede Azghandi Julia Werner Thorsten Kessler Rainer Malik Marta Murgia Zouhair Aherrahrou Heribert Schunkert Martin Dichgans Matthias Mann

Mol Cell Proteomics 2018 02 4;17(2):321-334. Epub 2017 Dec 4.

From the ‡Department of Proteomics and Signal Transduction, Max-Planck Institute of Biochemistry, Martinsried, Germany;

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http://www.mcponline.org/lookup/doi/10.1074/mcp.RA117.000315	Publisher Site
http://dx.doi.org/10.1074/mcp.RA117.000315	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5795394	PMC

February 2018

ApoA-I Mimetic Peptide 4F Reduces Age-Related Lipid Deposition in Murine Bruch's Membrane and Causes Its Structural Remodeling.

Authors:

Martin Rudolf Armin Mir Mohi Sefat Yoko Miura Aysegül Tura Walter Raasch Mahdy Ranjbar Salvatore Grisanti Zouhair Aherrahrou Anna Wagner Jeffrey D Messinger David W Garber G M Anantharamaiah Christine A Curcio

Curr Eye Res 2018 01 3;43(1):135-146. Epub 2017 Oct 3.

e Department of Ophthalmology , University of Alabama at Birmingham , Birmingham , AL , USA.

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http://dx.doi.org/10.1080/02713683.2017.1370118	DOI Listing

January 2018

Coronary artery disease associated gene Phactr1 modulates severity of vascular calcification in vitro.

Authors:

Redouane Aherrahrou Zouhair Aherrahrou Heribert Schunkert Jeanette Erdmann

Biochem Biophys Res Commun 2017 09 15;491(2):396-402. Epub 2017 Jul 15.

Institute for Cardiogenetics, University of Lübeck, DZHK (German Research Centre for Cardiovascular Research), Partner Site Hamburg/Lübeck/Kie, University Heart Center Luebeck, 23562 Lübeck, Germany.

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http://dx.doi.org/10.1016/j.bbrc.2017.07.090	DOI Listing

September 2017

Pyrophosphate Supplementation Prevents Chronic and Acute Calcification in ABCC6-Deficient Mice.

Authors:

Viola Pomozi Christopher Brampton Koen van de Wetering Janna Zoll Bianca Calio Kevin Pham Jesse B Owens Joel Marh Stefan Moisyadi András Váradi Ludovic Martin Carolin Bauer Jeanette Erdmann Zouhair Aherrahrou Olivier Le Saux

Am J Pathol 2017 Jun 14;187(6):1258-1272. Epub 2017 Apr 14.

Department of Cell and Molecular Biology, John A. Burns School of Medicine, University of Hawaii, Honolulu, Hawaii. Electronic address:

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http://dx.doi.org/10.1016/j.ajpath.2017.02.009	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5455066	PMC

June 2017

Proatherosclerotic Effect of the α1-Subunit of Soluble Guanylyl Cyclase by Promoting Smooth Muscle Phenotypic Switching.

Authors:

Maria Segura-Puimedon Evanthia Mergia Jaafar Al-Hasani Redouane Aherrahrou Stephanie Stoelting Felix Kremer Jennifer Freyer Doris Koesling Jeanette Erdmann Heribert Schunkert Cor de Wit Zouhair Aherrahrou

Am J Pathol 2016 08 15;186(8):2220-2231. Epub 2016 Jun 15.

Institute for Integrative and Experimental Genomics, University of Lübeck, DZHK (German Centre for Cardiovascular Research), Partner Site Hamburg/Kiel/Lübeck, University Heart Centre Lübeck, Lübeck, Germany. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00029440163012	Publisher Site
http://dx.doi.org/10.1016/j.ajpath.2016.04.010	DOI Listing

August 2016

Knock-out of nexilin in mice leads to dilated cardiomyopathy and endomyocardial fibroelastosis.

Authors:

Zouhair Aherrahrou Saskia Schlossarek Stephanie Stoelting Matthias Klinger Birgit Geertz Florian Weinberger Thorsten Kessler Redouane Aherrahrou Kristin Moreth Raffi Bekeredjian Martin Hrabě de Angelis Steffen Just Wolfgang Rottbauer Thomas Eschenhagen Heribert Schunkert Lucie Carrier Jeanette Erdmann

Basic Res Cardiol 2016 Jan 10;111(1). Epub 2015 Dec 10.

Institute for Integrative and Experimental Genomics, University of Lübeck, 23562, Lübeck, Germany.

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http://link.springer.com/content/pdf/10.1007/s00395-015-0522	Web Search
http://link.springer.com/10.1007/s00395-015-0522-5	Publisher Site
http://dx.doi.org/10.1007/s00395-015-0522-5	DOI Listing

January 2016

Identification of a novel ovine LH-beta promoter region, which dramatically enhances its promoter activity.

Authors:

Redouane Aherrahrou Zouhair Aherrahrou Jeanette Erdmann Mohieddine Moumni

Springerplus 2015 1;4:466. Epub 2015 Sep 1.

Department of Biology, Faculty of Sciences, Moulay Ismail University, Zitoune, BP 11201, 50000 Meknes, Morocco.

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http://dx.doi.org/10.1186/s40064-015-1182-5	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4554545	PMC

September 2015

ADAMTS-7 inhibits re-endothelialization of injured arteries and promotes vascular remodeling through cleavage of thrombospondin-1.

Authors:

Thorsten Kessler Lu Zhang Ziyi Liu Xiaoke Yin Yaqian Huang Yingbao Wang Yi Fu Manuel Mayr Qing Ge Qingbo Xu Yi Zhu Xian Wang Kjestine Schmidt Cor de Wit Jeanette Erdmann Heribert Schunkert Zouhair Aherrahrou Wei Kong

Circulation 2015 Mar 20;131(13):1191-201. Epub 2015 Feb 20.

From Deutsches Herzzentrum München, Klinik für Herz- und Kreislauferkrankungen, Technische Universität München, Germany (T.K., H.S.); Department of Physiology and Pathophysiology, School of Basic Medical Sciences, Peking University, Beijing, China (L.Z., Z.L.,Y.H.,Y.W., Y.F., X.W., W.K.); Key Laboratory of Molecular Cardiovascular Science, Ministry of Education, Beijing, China (L.Z., Z.L., Y.H., Y.W., Y.F., X.W., W.K.); Cardiovascular Division, Kings College London BHF Centre, United Kingdom (X.Y., M.M., Q.X.); Department of Immunology, School of Basic Medical Sciences, Peking University, Beijing, China (Q.G.); School of Basic Medical Sciences, Tianjin University, Beijing, China (Y.Z.); Institut für Physiologie, Universität zu Lübeck, Germany (K.S., C.d.W.); Deutsches Zentrum für Herz-Kreislauf-Forschung (DZHK) e.V. (German Center for Cardiovascular Research), partner site Hamburg/Kiel/Lübeck, Lübeck, Germany (K.S., C.d.W., J.E., Z.A.); Institut für Integrative und Experimentelle Genomik, Universität zu Lübeck, Germany (J.E., Z.A.); and Deutsches Zentrum für Herz-Kreislauf-Forschung (DZHK) e.V. (German Center for Cardiovascular Research), partner site Munich Heart Alliance (MHA), München, Germany (H.S.).

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http://dx.doi.org/10.1161/CIRCULATIONAHA.114.014072	DOI Listing

March 2015

Detection of esterified cholesterol in murine Bruch's membrane wholemounts with a perfringolysin O-based cholesterol marker.

Authors:

Martin Rudolf Armin Mohi Marie C Dettbarn Yoko Miura Zouhair Aherrahrou Mahdy Ranjbar Bulent Mutus Johannes K M Knobloch

Invest Ophthalmol Vis Sci 2014 Jul 1;55(8):4759-67. Epub 2014 Jul 1.

Institute for Medical Microbiology & Hygiene, University of Lübeck, Lübeck, Germany.

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http://dx.doi.org/10.1167/iovs.14-14311	DOI Listing

July 2014

The level of hepatic ABCC6 expression determines the severity of calcification after cardiac injury.

Authors:

Christopher Brampton Zouhair Aherrahrou Li-Hsieh Chen Ludovic Martin Arthur A B Bergen Theo G M F Gorgels Jeannette Erdmann Jeannette Erdfdi Heribert Schunkert Zalán Szabó András Váradi Olivier Le Saux

Am J Pathol 2014 Jan;184(1):159-70

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3873484	PMC
http://dx.doi.org/10.1016/j.ajpath.2013.09.015	DOI Listing

January 2014

Dysfunctional nitric oxide signalling increases risk of myocardial infarction.

Nature 2013 Dec 10;504(7480):432-6. Epub 2013 Nov 10.

1] Deutsches Herzzentrum München and 1. Medizinische Klinik, Klinikum rechts der Isar, Technische Universität München, 80636 München, Germany [2] German Centre for Cardiovascular Research (DZHK), partner site Munich Heart Alliance, 80636 Munich, Germany.

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http://dx.doi.org/10.1038/nature12722	DOI Listing

December 2013

Functional interaction of osteogenic transcription factors Runx2 and Vdr in transcriptional regulation of Opn during soft tissue calcification.

Authors:

Ann-Kathrin Sowa Frank J Kaiser Juliane Eckhold Thorsten Kessler Redouane Aherrahrou Sandra Wrobel Piotr M Kaczmarek Lars Doehring Heribert Schunkert Jeanette Erdmann Zouhair Aherrahrou

Am J Pathol 2013 Jul 2;183(1):60-8. Epub 2013 May 2.

Institute for Integrative and Experimental Genomics and DZHK-German Centre for Cardiovascular Research, partner site Lübeck/Hamburg/Kiel, University of Lübeck, Lübeck, Germany.

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http://dx.doi.org/10.1016/j.ajpath.2013.03.007	DOI Listing

July 2013

Genetics of atherosclerosis and vascular calcification go hand-in-hand.

Authors:

Zouhair Aherrahrou Heribert Schunkert

Atherosclerosis 2013 Jun 11;228(2):325-6. Epub 2012 Oct 11.

Universität zu Lübeck, Medizinische Klinik II, Lübeck, Germany.

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http://dx.doi.org/10.1016/j.atherosclerosis.2012.10.029	DOI Listing

June 2013

The molecular and physiological roles of ABCC6: more than meets the eye.

Authors:

Olivier Le Saux Ludovic Martin Zouhair Aherrahrou Georges Leftheriotis András Váradi Christopher N Brampton

Front Genet 2012 12;3:289. Epub 2012 Dec 12.

Department of Cell and Molecular Biology, John A. Burns School of Medicine, University of Hawaii Honolulu, HI, USA.

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http://dx.doi.org/10.3389/fgene.2012.00289	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3520154	PMC

December 2012

Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease.

Authors:

Heribert Schunkert Inke R König Sekar Kathiresan Muredach P Reilly Themistocles L Assimes Hilma Holm Michael Preuss Alexandre F R Stewart Maja Barbalic Christian Gieger Devin Absher Zouhair Aherrahrou Hooman Allayee David Altshuler Sonia S Anand Karl Andersen Jeffrey L Anderson Diego Ardissino Stephen G Ball Anthony J Balmforth Timothy A Barnes Diane M Becker Lewis C Becker Klaus Berger Joshua C Bis S Matthijs Boekholdt Eric Boerwinkle Peter S Braund Morris J Brown Mary Susan Burnett Ian Buysschaert John F Carlquist Li Chen Sven Cichon Veryan Codd Robert W Davies George Dedoussis Abbas Dehghan Serkalem Demissie Joseph M Devaney Patrick Diemert Ron Do Angela Doering Sandra Eifert Nour Eddine El Mokhtari Stephen G Ellis Roberto Elosua James C Engert Stephen E Epstein Ulf de Faire Marcus Fischer Aaron R Folsom Jennifer Freyer Bruna Gigante Domenico Girelli Solveig Gretarsdottir Vilmundur Gudnason Jeffrey R Gulcher Eran Halperin Naomi Hammond Stanley L Hazen Albert Hofman Benjamin D Horne Thomas Illig Carlos Iribarren Gregory T Jones J Wouter Jukema Michael A Kaiser Lee M Kaplan John J P Kastelein Kay-Tee Khaw Joshua W Knowles Genovefa Kolovou Augustine Kong Reijo Laaksonen Diether Lambrechts Karin Leander Guillaume Lettre Mingyao Li Wolfgang Lieb Christina Loley Andrew J Lotery Pier M Mannucci Seraya Maouche Nicola Martinelli Pascal P McKeown Christa Meisinger Thomas Meitinger Olle Melander Pier Angelica Merlini Vincent Mooser Thomas Morgan Thomas W Mühleisen Joseph B Muhlestein Thomas Münzel Kiran Musunuru Janja Nahrstaedt Christopher P Nelson Markus M Nöthen Oliviero Olivieri Riyaz S Patel Chris C Patterson Annette Peters Flora Peyvandi Liming Qu Arshed A Quyyumi Daniel J Rader Loukianos S Rallidis Catherine Rice Frits R Rosendaal Diana Rubin Veikko Salomaa M Lourdes Sampietro Manj S Sandhu Eric Schadt Arne Schäfer Arne Schillert Stefan Schreiber Jürgen Schrezenmeir Stephen M Schwartz David S Siscovick Mohan Sivananthan Suthesh Sivapalaratnam Albert Smith Tamara B Smith Jaapjan D Snoep Nicole Soranzo John A Spertus Klaus Stark Kathy Stirrups Monika Stoll W H Wilson Tang Stephanie Tennstedt Gudmundur Thorgeirsson Gudmar Thorleifsson Maciej Tomaszewski Andre G Uitterlinden Andre M van Rij Benjamin F Voight Nick J Wareham George A Wells H-Erich Wichmann Philipp S Wild Christina Willenborg Jaqueline C M Witteman Benjamin J Wright Shu Ye Tanja Zeller Andreas Ziegler Francois Cambien Alison H Goodall L Adrienne Cupples Thomas Quertermous Winfried März Christian Hengstenberg Stefan Blankenberg Willem H Ouwehand Alistair S Hall Panos Deloukas John R Thompson Kari Stefansson Robert Roberts Unnur Thorsteinsdottir Christopher J O'Donnell Ruth McPherson Jeanette Erdmann Nilesh J Samani

Nat Genet 2011 Mar 6;43(4):333-8. Epub 2011 Mar 6.

Universität zu Lübeck, Medizinische Klinik II, Lübeck, Germany.

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http://dx.doi.org/10.1038/ng.784	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3119261	PMC

March 2011

Genome-wide association study identifies a new locus for coronary artery disease on chromosome 10p11.23.

Eur Heart J 2011 Jan 18;32(2):158-68. Epub 2010 Nov 18.

Medizinische Klinik II, Universität zu Lübeck, Lübeck, Germany.

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http://eurheartj.oxfordjournals.org/content/ehj/32/2/158.ful	Web Search
http://eurheartj.oxfordjournals.org/cgi/doi/10.1093/eurheart	Publisher Site
http://dx.doi.org/10.1093/eurheartj/ehq405	DOI Listing