Publications by authors named "Zohreh Hosseinkhani"

2 Publications

  • Page 1 of 1

Adaptive Real-Time Removal of Impulse Noise in Medical Images.

J Med Syst 2018 Oct 2;42(11):216. Epub 2018 Oct 2.

Department of Electrical and Computer Engineering, Isfahan University of Technology, Isfahan, 84156-83111, Iran.

Noise is an important factor that degrades the quality of medical images. Impulse noise is a common noise caused by malfunctioning of sensor elements or errors in the transmission of images. In medical images due to presence of white foreground and black background, many pixels have intensities similar to impulse noise and hence the distinction between noisy and regular pixels is difficult. Therefore, it is important to design a method to accurately remove this type of noise. In addition to the accuracy, the complexity of the method is very important in terms of hardware implementation. In this paper a low complexity de-noising method is proposed that distinguishes between noisy and non-noisy pixels and removes the noise by local analysis of the image blocks. All steps are designed to have low hardware complexity. Simulation results show that in the case of magnetic resonance images, the proposed method removes impulse noise with an acceptable accuracy.
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October 2018

The effect of , , and polymorphism in patients under warfarin therapy in city of Kermanshah.

Res Pharm Sci 2018 Aug;13(4):377-384

Medical Biology Research Center, Kermanshah University of Medical Sciences, Kermanshah, I.R. Iran.

Polymorphism in the genes encoding enzyme and reductase significantly influence warfarin dose requirement since patients with , and mutant alleles require lower warfarin maintenance doses. Studies have reported the ethnic variations in the frequency of these genes within the various populations in Iran and other parts of the world. However, no such study has been done yet on Kurdish population in Kermanshah. From Kurdish population of Kermanshah province in Iran, a total of 110 patients who had heart surgery and taking warfarin, were genotyped for polymorphisms of , , and . Polymorphism genotyping was performed by sequencing as well as polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) using restriction enzymes of and , respectively. The frequencies of -1639 GG, GA, and AA genotypes were 42%, 36%, and 22%, respectively and for 1*/1*, 1*/2*, 2*/2*, 1*/3*, 3*/3*, 2*/3* were 71%, 17%, 5.4%, 1.8%, 4.5%, and 0%, respectively. The frequency of -1639A allele was 42.3% and the frequencies of and *3 alleles were 14% and 5.4%, respectively. It was indicated that low warfarin dose requirements are strongly associated with the presence of and variant alleles. Our results confirmed the supply to understand the distribution of genomic biomarkers related to the drugs metabolism for future planning health programs.
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August 2018