Zlatko Trajanoski

Zlatko Trajanoski

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Zlatko Trajanoski

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Microbial Colonization in Adulthood Shapes the Intestinal Macrophage Compartment.

J Crohns Colitis 2019 Sep;13(9):1173-1185

Medizinische Klinik für Gastroenterologie, Infektiologie und Rheumatologie, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Berlin, Germany.

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http://dx.doi.org/10.1093/ecco-jcc/jjz036DOI Listing
September 2019

Next-generation computational tools for interrogating cancer immunity.

Nat Rev Genet 2019 Sep 12. Epub 2019 Sep 12.

Biocenter, Institute of Bioinformatics, Medical University of Innsbruck, Innsbruck, Austria.

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http://dx.doi.org/10.1038/s41576-019-0166-7DOI Listing
September 2019

Advancing cancer immunotherapy: a vision for the field.

Genome Med 2019 07 29;11(1):51. Epub 2019 Jul 29.

Biocenter, Institute of Bioinformatics, Medical University of Innsbruck, Innrain, 6020, Innsbruck, Austria.

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http://dx.doi.org/10.1186/s13073-019-0662-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6661948PMC
July 2019

Mutational and Antigenic Landscape in Tumor Progression and Cancer Immunotherapy.

Trends Cell Biol 2019 May 11;29(5):396-416. Epub 2019 Feb 11.

Department of Radiation Oncology, Weill Cornell Medical College, New York, NY, USA; Sandra and Edward Meyer Cancer Center, New York, NY, USA; Department of Dermatology, Yale University School of Medicine, New Haven, CT, USA; Université Paris Descartes/Paris V, Paris, France; Co-senior authors. Electronic address:

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http://dx.doi.org/10.1016/j.tcb.2019.01.003DOI Listing
May 2019

Adoptive T Cell Therapy: New Avenues Leading to Safe Targets and Powerful Allies.

Trends Immunol 2018 11 9;39(11):921-936. Epub 2018 Oct 9.

Laboratory of Tumor Immunology, Erasmus MC-Cancer Institute, Rotterdam, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.it.2018.09.004DOI Listing
November 2018

Quantifying tumor-infiltrating immune cells from transcriptomics data.

Cancer Immunol Immunother 2018 07 14;67(7):1031-1040. Epub 2018 Mar 14.

Biocenter, Division for Bioinformatics, Medical University of Innsbruck, Innrain 80, 6020, Innsbruck, Austria.

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http://dx.doi.org/10.1007/s00262-018-2150-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6006237PMC
July 2018

Neoantigens Generated by Individual Mutations and Their Role in Cancer Immunity and Immunotherapy.

Front Immunol 2017 28;8:1679. Epub 2017 Nov 28.

Biocenter, Division of Bioinformatics, Medical University of Innsbruck, Innsbruck, Austria.

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http://dx.doi.org/10.3389/fimmu.2017.01679DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5712389PMC
November 2017

TIminer: NGS data mining pipeline for cancer immunology and immunotherapy.

Bioinformatics 2017 Oct;33(19):3140-3141

Division of Bioinformatics, Biocenter, Medical University of Innsbruck, 6020 Innsbruck, Austria.

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http://dx.doi.org/10.1093/bioinformatics/btx377DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5870678PMC
October 2017

Reduced CD62L Expression on T Cells and Increased Soluble CD62L Levels Predict Molecular Response to Tyrosine Kinase Inhibitor Therapy in Early Chronic-Phase Chronic Myelogenous Leukemia.

J Clin Oncol 2017 Jan 7;35(2):175-184. Epub 2016 Nov 7.

Sieghart Sopper, Günther Gastl, Matthias Baldauf, Zlatko Trajanoski, and Dominik Wolf, Medical University Innsbruck; Sieghart Sopper and Dominik Wolf, Tyrolean Cancer Research Institute; Matthias Baldauf, Oncotyrol, Innsbruck; Peter Valent, Medical University of Vienna, Vienna, Austria; Satu Mustjoki and Kimmo Porkka, University of Helsinki and Helsinki University Hospital Comprehensive Cancer Center, Helsinki, Finland; Deborah White and Timothy Hughes, South Australian Health and Medical Research Institute and University of Adelaide School of Medicine, Adelaide, South Australia, Australia; Andreas Burchert, Universitätsklinikum Gießen und Marburg and Philipps Universität Marburg, Marburg; Andreas Hochhaus, Thomas Ernst, and Thomas Schenk, Universitätsklinikum Jena, Jena; Dominik Wolf, University Hospital of Bonn, Bonn, Germany; Bjørn T. Gjertsen, University of Bergen, Bergen, Norway; Frank Giles, Northwestern University, Chicago, IL; and Jeroen J.W.M. Janssen and Gert J. Ossenkoppele, Vrije Universiteit Medical Center, Amsterdam, the Netherlands.

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http://dx.doi.org/10.1200/JCO.2016.67.0893DOI Listing
January 2017

New strategies for cancer immunotherapy: targeting regulatory T cells.

Genome Med 2017 01 27;9(1):10. Epub 2017 Jan 27.

Biocenter, Division of Bioinformatics, Medical University of Innsbruck, Innsbruck, 6020, Austria.

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http://dx.doi.org/10.1186/s13073-017-0402-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5273791PMC
January 2017

Differential cytokine sensitivities of STAT5-dependent enhancers rely on Stat5 autoregulation.

Nucleic Acids Res 2016 Dec 30;44(21):10277-10291. Epub 2016 Sep 30.

Laboratory of Genetics and Physiology, National Institute of Diabetes and Digestive and Kidney Diseases, US National Institutes of Health, Bethesda, MD 20892, USA

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http://dx.doi.org/10.1093/nar/gkw844DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5137441PMC
December 2016

Computational genomics tools for dissecting tumour-immune cell interactions.

Nat Rev Genet 2016 07;17(8):441-58

Division of Bioinformatics, Biocenter, Medical University of Innsbruck, Innrain 80-82, 6020 Innsbruck, Austria.

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http://dx.doi.org/10.1038/nrg.2016.67DOI Listing
July 2016

miR-22 and miR-29a Are Members of the Androgen Receptor Cistrome Modulating LAMC1 and Mcl-1 in Prostate Cancer.

Mol Endocrinol 2015 Jul 8;29(7):1037-54. Epub 2015 Jun 8.

Department of Urology (L.P., H.B., M.P., B.S., G.S., H.K.), Division of Experimental Urology, Medical University of Innsbruck, 6020 Innsbruck, Austria; Research Institute for Biomedical Aging Research (H.B.), University of Innsbruck, 6020 Innsbruck, Austria; Medical Genomics and Metabolic Genetics Branch (N.N.), National Human Genome Research Institute, National Institutes of Health, Bethesda, Maryland 20892; Biocenter Innsbruck (J.R.), Section for Molecular Pathophysiology, Medical University of Innsbruck, 6020 Innsbruck, Austria; Center for Biomedicine (J.R., C.F.), EURAC Bolzano, 39100 Bolzano, Italy; Oncotyrol (B.S.), Center for Personalized Cancer Medicine, 6020 Innsbruck, Austria; Department of Pathology (G.S.), Medical University of Innsbruck, 6020 Innsbruck, Austria; Biocenter Innsbruck (M.A., Z.T.), Division of Bioinformatics, Medical University of Innsbruck, 6020 Innsbruck, Austria; Max Planck Institute for Molecular Genetics (S.T.B., M.R.S.), 14195 Berlin, Germany; Cologne Center for Genomics (M.R.S.), University of Cologne, 50931 Cologne, Germany; and Department of Biostatistic (C.F.), University of Michigan, Ann Arbor, Michigan 48109.

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http://dx.doi.org/10.1210/me.2014-1358DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4484780PMC
July 2015

Somatically mutated tumor antigens in the quest for a more efficacious patient-oriented immunotherapy of cancer.

Cancer Immunol Immunother 2015 Jan 28;64(1):99-104. Epub 2014 Aug 28.

Biocenter, Division for Bioinformatics, Innsbruck Medical University, Innrain 80, 6020, Innsbruck, Austria.

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http://dx.doi.org/10.1007/s00262-014-1599-7DOI Listing
January 2015

Personalized Oncology Suite: integrating next-generation sequencing data and whole-slide bioimages.

BMC Bioinformatics 2014 Sep 18;15:306. Epub 2014 Sep 18.

Division for Bioinformatics, Biocenter, Innsbruck Medical University, Innrain 80-82, 6020 Innsbruck, Austria.

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http://dx.doi.org/10.1186/1471-2105-15-306DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4261581PMC
September 2014

MEMOSys 2.0: an update of the bioinformatics database for genome-scale models and genomic data.

Database (Oxford) 2014 14;2014:bau004. Epub 2014 Feb 14.

Division for Bioinformatics, Innsbruck Medical University, 6020 Innsbruck, Austria, Health & Environment Department, AIT-Austrian Institute of Technology, Molecular Diagnostics, 1190 Vienna, Austria, Oncotyrol, Center for Personalized Cancer Medicine, 6020 Innsbruck, Austria and Development Anti-Infectives Microbiology, Sandoz GmbH, 6250 Kundl, Austria.

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http://dx.doi.org/10.1093/database/bau004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3924767PMC
August 2014

SPARQLGraph: a web-based platform for graphically querying biological Semantic Web databases.

BMC Bioinformatics 2014 Aug 15;15:279. Epub 2014 Aug 15.

Division for Bioinformatics, Biocenter, Innsbruck Medical University, Innsbruck, Austria.

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http://dx.doi.org/10.1186/1471-2105-15-279DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4148538PMC
August 2014

Co-expressed genes prepositioned in spatial neighborhoods stochastically associate with SC35 speckles and RNA polymerase II factories.

Cell Mol Life Sci 2014 May 12;71(9):1741-59. Epub 2013 Sep 12.

Division of Bioinformatics, Biocenter, Innsbruck Medical University, Innrain 80, 6020, Innsbruck, Austria.

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http://dx.doi.org/10.1007/s00018-013-1465-3DOI Listing
May 2014

A survey of tools for variant analysis of next-generation genome sequencing data.

Brief Bioinform 2014 Mar 21;15(2):256-78. Epub 2013 Jan 21.

Division for Bioinformatics, Innsbruck Medical University, Innrain 80, 6020 Innsbruck, Austria. Tel.: +43-512-9003-71401; Fax: +43-512-9003-73100;

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http://dx.doi.org/10.1093/bib/bbs086DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3956068PMC
March 2014

SeqBench: integrated solution for the management and analysis of exome sequencing data.

BMC Res Notes 2014 Jan 20;7:43. Epub 2014 Jan 20.

Division for Bioinformatics, Biocenter, Innsbruck Medical University, Innsbruck, Austria.

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http://dx.doi.org/10.1186/1756-0500-7-43DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3898724PMC
January 2014

Mathematical models for translational and clinical oncology.

J Clin Bioinforma 2013 Nov 7;3(1):23. Epub 2013 Nov 7.

Biocenter, Division of Bioinformatics, Innsbruck Medical University, Innrain 80, 6020 Innsbruck, Austria.

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http://dx.doi.org/10.1186/2043-9113-3-23DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3828625PMC
November 2013

Spatiotemporal dynamics of intratumoral immune cells reveal the immune landscape in human cancer.

Immunity 2013 Oct;39(4):782-95

INSERM U872, Laboratory of Integrative Cancer Immunology, Paris 75006, France; Université Paris Descartes, Paris 75006, France; Cordeliers Research Centre, Université Pierre et Marie Curie Paris 6, Paris 75006, France.

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http://dx.doi.org/10.1016/j.immuni.2013.10.003DOI Listing
October 2013

GPViz: dynamic visualization of genomic regions and variants affecting protein domains.

Bioinformatics 2013 Sep 19;29(17):2195-6. Epub 2013 Jun 19.

Biocenter, Division of Bioinformatics, Innsbruck Medical University and Oncotyrol Center for Personalized Cancer Medicine GmbH, 6020 Innsbruck, Austria.

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http://dx.doi.org/10.1093/bioinformatics/btt354DOI Listing
September 2013

Genome-scale model management and comparison.

Methods Mol Biol 2013 ;985:3-16

Division for Bioinformatics, Biocenter, Innsbruck Medical University, Innsbruck, Austria.

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http://dx.doi.org/10.1007/978-1-62703-299-5_1DOI Listing
July 2013

Nr4a1 is required for fasting-induced down-regulation of Pparγ2 in white adipose tissue.

Mol Endocrinol 2013 Jan 18;27(1):135-49. Epub 2012 Dec 18.

Division of Bioinformatics, Biocenter, Innsbruck Medical University, 6020 Innsbruck, Austria.

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http://dx.doi.org/10.1210/me.2012-1248DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5416946PMC
January 2013

Bioinformatics for cancer immunology and immunotherapy.

Cancer Immunol Immunother 2012 Nov 18;61(11):1885-903. Epub 2012 Sep 18.

Biocenter, Division of Bioinformatics, Innsbruck Medical University, Innrain 80, 6020, Innsbruck, Austria.

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http://dx.doi.org/10.1007/s00262-012-1354-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3493665PMC
November 2012

Transcription factories.

Front Genet 2012 23;3:221. Epub 2012 Oct 23.

Division of Bioinformatics, Biocenter, Innsbruck Medical University Innsbruck, Austria.

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http://dx.doi.org/10.3389/fgene.2012.00221DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3478587PMC
October 2012

Insights into global mechanisms and disease by gene expression profiling.

Methods Mol Biol 2011 ;719:269-98

Genomics Unit, Centro Nacional de Investigaciones Cardiovasculares, Madrid, Spain.

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http://dx.doi.org/10.1007/978-1-61779-027-0_13DOI Listing
June 2011

GiSAO.db: a database for ageing research.

BMC Genomics 2011 May 24;12:262. Epub 2011 May 24.

Division for Bioinformatics, Biocenter, Innsbruck Medical University, Schöpfstrasse, Austria.

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http://dx.doi.org/10.1186/1471-2164-12-262DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3113790PMC
May 2011

MEMOSys: Bioinformatics platform for genome-scale metabolic models.

BMC Syst Biol 2011 Jan 31;5:20. Epub 2011 Jan 31.

Institute for Genomics and Bioinformatics, Graz University of Technology, Petersgasse 14, 8010 Graz, Austria.

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http://dx.doi.org/10.1186/1752-0509-5-20DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3045322PMC
January 2011

Information technology solutions for integration of biomolecular and clinical data in the identification of new cancer biomarkers and targets for therapy.

Pharmacol Ther 2010 Dec 9;128(3):488-98. Epub 2010 Sep 9.

Biocenter, Section for Bioinformatics, Innsbruck Medical University, Schöpfstrasse 45, 6020, Innsbruck, Austria.

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http://dx.doi.org/10.1016/j.pharmthera.2010.08.012DOI Listing
December 2010

Identification of differential and functionally active miRNAs in both anaplastic lymphoma kinase (ALK)+ and ALK- anaplastic large-cell lymphoma.

Proc Natl Acad Sci U S A 2010 Sep 30;107(37):16228-33. Epub 2010 Aug 30.

Laboratory for Immunological and Molecular Cancer Research, Third Medical Department with Hematology, Paracelsus Medical University Salzburg, 5020 Salzburg, Austria.

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http://dx.doi.org/10.1073/pnas.1009719107DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2941277PMC
September 2010

Novel insights into adipogenesis from omics data.

Curr Med Chem 2009 ;16(23):2952-64

Institute for Genomics and Bioinformatics, Graz University of Technology, Graz, Austria.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2765082PMC
http://dx.doi.org/10.2174/092986709788803132DOI Listing
November 2009

iLAP: a workflow-driven software for experimental protocol development, data acquisition and analysis.

BMC Bioinformatics 2009 Nov 26;10:390. Epub 2009 Nov 26.

Institute for Genomics and Bioinformatics, Graz University of Technology, Petersgasse 14, 8010 Graz, Austria.

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http://dx.doi.org/10.1186/1471-2105-10-390DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2789074PMC
November 2009

QPCR: Application for real-time PCR data management and analysis.

BMC Bioinformatics 2009 Aug 27;10:268. Epub 2009 Aug 27.

Institute for Genomics and Bioinformatics, Graz University of Technology, Petersgasse 14, 8010 Graz, Austria.

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http://dx.doi.org/10.1186/1471-2105-10-268DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2741456PMC
August 2009

Stathmin-like 2, a developmentally-associated neuronal marker, is expressed and modulated during osteogenesis of human mesenchymal stem cells.

Biochem Biophys Res Commun 2008 Sep 9;374(1):64-8. Epub 2008 Jul 9.

IBDC, Université de Nice Sophia-Antipolis, CNRS, 28 Avenue Valrose, 06108 Nice cedex 2, France.

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http://dx.doi.org/10.1016/j.bbrc.2008.06.121DOI Listing
September 2008

Comparative transcriptomics of human multipotent stem cells during adipogenesis and osteoblastogenesis.

BMC Genomics 2008 Jul 17;9:340. Epub 2008 Jul 17.

Institute for Genomics and Bioinformatics and Christian Doppler Laboratory for Genomics and Bioinformatics, Graz University of Technology, Petersgasse 14, 8010 Graz, Austria.

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http://dx.doi.org/10.1186/1471-2164-9-340DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2492879PMC
July 2008

Arsenic trioxide induces apoptosis preferentially in B-CLL cells of patients with unfavourable prognostic factors including del17p13.

J Mol Med (Berl) 2008 May 23;86(5):541-52. Epub 2008 Feb 23.

Laboratory for Immunological and Molecular Cancer Research, IIIrd Medical Department with Hematology, Medical Oncology, Hemostaseology, Rheumatology and Infectiology, Paracelsus Medical University Salzburg, Salzburg, Austria.

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http://dx.doi.org/10.1007/s00109-008-0314-6DOI Listing
May 2008

The phosphatidylethanolamine level of yeast mitochondria is affected by the mitochondrial components Oxa1p and Yme1p.

FEBS J 2007 Dec 1;274(23):6180-90. Epub 2007 Nov 1.

Institute of Biochemistry, Graz University of Technology, Austria.

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http://dx.doi.org/10.1111/j.1742-4658.2007.06138.xDOI Listing
December 2007

A new platform linking chromosomal and sequence information.

Chromosome Res 2007 10;15(3):327-39. Epub 2007 May 10.

CCRI, Children's Cancer Research Institute, St. Anna Kinderkrebsforschung, 1090, Vienna, Austria.

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http://dx.doi.org/10.1007/s10577-007-1129-yDOI Listing
August 2007

MASPECTRAS: a platform for management and analysis of proteomics LC-MS/MS data.

BMC Bioinformatics 2007 Jun 13;8:197. Epub 2007 Jun 13.

Institute for Genomics and Bioinformatics and Christian-Doppler Laboratory for Genomics and Bioinformatics, Graz University of Technology, Petersgasse 14, Graz, Austria.

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http://dx.doi.org/10.1186/1471-2105-8-197DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1906842PMC
June 2007

Organization of chromatin and histone modifications at a transcription site.

J Cell Biol 2007 Jun;177(6):957-67

Laboratory of Receptor Biology and Gene Expression, National Cancer Institute, Bethesda, MD 20892, USA.

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http://dx.doi.org/10.1083/jcb.200703157DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2064357PMC
June 2007

TAMEE: data management and analysis for tissue microarrays.

BMC Bioinformatics 2007 Mar 7;8:81. Epub 2007 Mar 7.

Institute for Genomics and Bioinformatics, Graz University of Technology, Petersgasse 14, 8010 Graz, Austria.

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http://dx.doi.org/10.1186/1471-2105-8-81DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1838435PMC
March 2007

LPL-mediated lipolysis of VLDL induces an upregulation of AU-rich mRNAs and an activation of HuR in endothelial cells.

Atherosclerosis 2006 Dec 21;189(2):310-7. Epub 2006 Feb 21.

Institute of Molecular Biosciences, Karl-Franzens-University, Graz, Heinrichstrasse 31 a, 8010 Graz, Austria.

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http://linkinghub.elsevier.com/retrieve/pii/S002191500600033
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http://dx.doi.org/10.1016/j.atherosclerosis.2006.01.007DOI Listing
December 2006

Molecular processes during fat cell development revealed by gene expression profiling and functional annotation.

Genome Biol 2005 19;6(13):R108. Epub 2005 Dec 19.

Institute for Genomics and Bioinformatics and Christian Doppler Laboratory for Genomics and Bioinformatics, Graz University of Technology, Petersgasse 14, 8010 Graz, Austria.

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http://genomebiology.biomedcentral.com/articles/10.1186/gb-2
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http://dx.doi.org/10.1186/gb-2005-6-13-r108DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1414107PMC
July 2006

CARMAweb: comprehensive R- and bioconductor-based web service for microarray data analysis.

Nucleic Acids Res 2006 Jul;34(Web Server issue):W498-503

Institute for Genomics and Bioinformatics, Graz University of Technology, Petersgasse 14, 8010 Graz, Austria.

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http://dx.doi.org/10.1093/nar/gkl038DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1538903PMC
July 2006

Effector memory T cells, early metastasis, and survival in colorectal cancer.

N Engl J Med 2005 Dec;353(25):2654-66

INSERM Unité 255, René Descartes Faculté de Médecine, Assistance Publique-Hôpitaux de Paris, Cordeliers Biomedical Research Center, University Paris 6, Paris, France.

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http://dx.doi.org/10.1056/NEJMoa051424DOI Listing
December 2005

Systems for the management of pharmacogenomic information.

Methods Mol Biol 2005 ;311:193-208

Institute for Genomics and Bioinformatics, Graz University of Technology, Graz, Austria.

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http://dx.doi.org/10.1385/1-59259-957-5:193DOI Listing
November 2005

The role of intramyocellular lipids during hypoglycemia in patients with intensively treated type 1 diabetes.

J Clin Endocrinol Metab 2005 Oct 5;90(10):5559-65. Epub 2005 Jul 5.

Division of Endocrinology and Metabolism, Department of Internal Medicine III, Medical University of Vienna, Austria.

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https://academic.oup.com/jcem/article-lookup/doi/10.1210/jc.
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http://dx.doi.org/10.1210/jc.2004-1756DOI Listing
October 2005

PathwayExplorer: web service for visualizing high-throughput expression data on biological pathways.

Nucleic Acids Res 2005 Jul;33(Web Server issue):W633-7

Institute for Genomics and Bioinformatics and Christian-Doppler Laboratory for Genomics and Bioinformatics, Graz University of Technology, Petersgasse 14, Graz 8010, Austria.

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http://dx.doi.org/10.1093/nar/gki391DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1160152PMC
July 2005