Ziyuan Zhou

Ziyuan Zhou

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Ziyuan Zhou

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Human Acetyl-CoA Carboxylase 1 Is an Isomerase: Carboxyl Transfer Is Activated by Catalytic Effect of Isomerization.

J Phys Chem B 2019 Aug 25;123(31):6757-6764. Epub 2019 Jul 25.

School of Biological Science and Technology , University of Jinan , Jinan 250022 , China.

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http://dx.doi.org/10.1021/acs.jpcb.9b05384DOI Listing
August 2019

Directional assembly of a stapled α-helical peptide.

Chem Commun (Camb) 2019 Aug;55(70):10484-10487

State Key Laboratory of Chemical Oncogenomics, School of Chemical Biology and Biotechnology, Shenzhen Graduate School, Peking University, Shenzhen 518055, China.

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http://xlink.rsc.org/?DOI=C9CC04591K
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http://dx.doi.org/10.1039/c9cc04591kDOI Listing
August 2019

Design and synthesis of novel hydrocarbylidene nitrohydrazinecarboximidamides against aphids based on natural product galegine.

Nat Prod Res 2019 Aug 20:1-7. Epub 2019 Aug 20.

College of Agriculture, Yangtze University , Jinzhou , China.

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http://dx.doi.org/10.1080/14786419.2019.1655409DOI Listing
August 2019

PERK regulates Nrf2/ARE antioxidant pathway against dibutyl phthalate-induced mitochondrial damage and apoptosis dependent of reactive oxygen species in mouse spermatocyte-derived cells.

Toxicol Lett 2019 Jun 23;308:24-33. Epub 2019 Mar 23.

Key Lab of Medical Protection for Electromagnetic Radiation, Ministry of Education of China, Institute of Toxicology, College of Preventive Medicine, Third Military Medical University, Chongqing, 400038, China. Electronic address:

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http://dx.doi.org/10.1016/j.toxlet.2019.03.007DOI Listing
June 2019

Development of a long-acting Fc-fused cocaine hydrolase with improved yield of protein expression.

Chem Biol Interact 2019 Jun 12;306:89-95. Epub 2019 Apr 12.

Molecular Modeling and Biopharmaceutical Center and Department of Pharmaceutical Sciences, College of Pharmacy, University of Kentucky, 789 South Limestone Street, Lexington, KY, 40536, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00092797193035
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http://dx.doi.org/10.1016/j.cbi.2019.04.012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6555559PMC
June 2019

Low f-Number Diffraction-Limited Pancharatnam-Berry Microlenses Enabled by Plasmonic Photopatterning of Liquid Crystal Polymers.

Adv Mater 2019 May 25;31(18):e1808028. Epub 2019 Mar 25.

Advanced Materials and Liquid Crystal Institute, Kent State University, Kent, OH, 44242, USA.

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http://dx.doi.org/10.1002/adma.201808028DOI Listing
May 2019

Autophagy inducing cyclic peptides constructed by methionine alkylation.

Chem Commun (Camb) 2019 Apr;55(29):4198-4201

State Key laboratory of Chemical Oncogenomics, School of Chemical Biology and Biotechnology, Peking University Shenzhen Graduate School, Shenzhen, 518055, P. R. China.

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http://dx.doi.org/10.1039/c9cc01027kDOI Listing
April 2019

Peptide-Aptamer Coassembly Nanocarrier for Cancer Therapy.

Bioconjug Chem 2019 Mar 7;30(3):536-540. Epub 2019 Feb 7.

State Key Laboratory of Chemical Oncogenomics, School of Chemical Biology and Biotechnology , Peking University Shenzhen Graduate School , Shenzhen 518055 , China.

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http://pubs.acs.org/doi/10.1021/acs.bioconjchem.8b00903
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http://dx.doi.org/10.1021/acs.bioconjchem.8b00903DOI Listing
March 2019

Mitochondrial functionality modifies human sperm acrosin activity, acrosome reaction capability and chromatin integrity.

Hum Reprod 2019 Jan;34(1):3-11

Key Lab of Medical Protection for Electromagnetic Radiation, Ministry of Education of China, Institute of Toxicology, College of Preventive Medicine, Third Military Medical University, Chongqing, China.

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https://academic.oup.com/humrep/advance-article/doi/10.1093/
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http://dx.doi.org/10.1093/humrep/dey335DOI Listing
January 2019

Lignocellulosic biomass to biofuels and biochemicals: A comprehensive review with a focus on ethanol organosolv pretreatment technology.

Biotechnol Bioeng 2018 11 15;115(11):2683-2702. Epub 2018 Sep 15.

Department of Chemistry and Chemical Engineering, MOE Engineering Research Center of Forestry Biomass Materials and Bioenergy, Beijing Forestry University, Beijing, China.

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http://dx.doi.org/10.1002/bit.26788DOI Listing
November 2018

Design, synthesis, and discovery of 5-((1,3-diphenyl-1H-pyrazol-4-yl)methylene)pyrimidine-2,4,6(1H,3H,5H)-triones and related derivatives as novel inhibitors of mPGES-1.

Bioorg Med Chem Lett 2018 03 8;28(5):858-862. Epub 2018 Feb 8.

Molecular Modeling and Biopharmaceutical Center, College of Pharmacy, University of Kentucky, 789 South Limestone Street, Lexington, KY 40536, United States; Department of Pharmaceutical Sciences, College of Pharmacy, University of Kentucky, 789 South Lime-stone Street, Lexington, KY 40536, United States; Center for Pharmaceutical Research and Innovation, College of Pharmacy, University of Kentucky, 789 South Limestone Street, Lexington, KY 40536, United States. Electronic address:

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http://dx.doi.org/10.1016/j.bmcl.2018.02.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5836806PMC
March 2018

Development of Fc-Fused Cocaine Hydrolase for Cocaine Addiction Treatment: Catalytic and Pharmacokinetic Properties.

AAPS J 2018 03 19;20(3):53. Epub 2018 Mar 19.

Molecular Modeling and Biopharmaceutical Center (MMBC) and Department of Pharmaceutical Sciences, College of Pharmacy, University of Kentucky, 789 South Limestone Street, Lexington, KY, 40536, USA.

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http://link.springer.com/10.1208/s12248-018-0214-9
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http://dx.doi.org/10.1208/s12248-018-0214-9DOI Listing
March 2018

Structure-based discovery of mPGES-1 inhibitors suitable for preclinical testing in wild-type mice as a new generation of anti-inflammatory drugs.

Sci Rep 2018 03 26;8(1):5205. Epub 2018 Mar 26.

Molecular Modeling and Biopharmaceutical Center, College of Pharmacy, University of Kentucky, 789 South Limestone Street, Lexington, KY, 40536, USA.

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http://dx.doi.org/10.1038/s41598-018-23482-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5979965PMC
March 2018

Exposures to Atmospheric PM and PM Affect Male Semen Quality: Results of MARHCS Study.

Environ Sci Technol 2018 02 24;52(3):1571-1581. Epub 2018 Jan 24.

Key Lab of Medical Protection for Electromagnetic Radiation, Ministry of Education of China, Institute of Toxicology, College of Preventive Medicine, Third Military Medical University , Chongqing, China.

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http://dx.doi.org/10.1021/acs.est.7b05206DOI Listing
February 2018

Clinical Potential of an Enzyme-based Novel Therapy for Cocaine Overdose.

Sci Rep 2017 11 10;7(1):15303. Epub 2017 Nov 10.

Molecular Modeling and Biopharmaceutical Center, College of Pharmacy, University of Kentucky, 789 South Limestone Street, Lexington, KY, 40536, USA.

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http://www.nature.com/articles/s41598-017-14105-5
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http://dx.doi.org/10.1038/s41598-017-14105-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5681513PMC
November 2017

Effectiveness of a Cocaine Hydrolase for Cocaine Toxicity Treatment in Male and Female Rats.

AAPS J 2017 11 27;20(1). Epub 2017 Nov 27.

Molecular Modeling and Biopharmaceutical Center, College of Pharmacy, University of Kentucky, 789 South Limestone Street, Lexington, Kentucky, 40536, USA.

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http://dx.doi.org/10.1208/s12248-017-0167-4DOI Listing
November 2017

Selective inhibitors of human mPGES-1 from structure-based computational screening.

Bioorg Med Chem Lett 2017 08 29;27(16):3739-3743. Epub 2017 Jun 29.

Molecular Modeling and Biopharmaceutical Center, College of Pharmacy, University of Kentucky, 789 South Limestone Street, Lexington, KY 40536, United States; Department of Pharmaceutical Sciences, College of Pharmacy, University of Kentucky, 789 South Limestone Street, Lexington, KY 40536, United States; Center for Pharmaceutical Research and Innovation, College of Pharmacy, University of Kentucky, 789 South Limestone Street, Lexington, KY 40536, United States.

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http://dx.doi.org/10.1016/j.bmcl.2017.06.075DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5586502PMC
August 2017

Mitochondrial Biomarkers Reflect Semen Quality: Results from the MARCHS Study in Chongqing, China.

PLoS One 2016 22;11(12):e0168823. Epub 2016 Dec 22.

Institute of Toxicology, College of Preventive Medicine, Third Military Medical University, Chongqing, China.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0168823PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5179063PMC
July 2017

Phthalate exposure, even below US EPA reference doses, was associated with semen quality and reproductive hormones: Prospective MARHCS study in general population.

Environ Int 2017 07 25;104:58-68. Epub 2017 Apr 25.

Key Lab of Medical Protection for Electromagnetic Radiation, Ministry of Education of China, Institute of Toxicology, College of Preventive Medicine, Third Military Medical University, Gaotanyan St 30, Chongqing 400038, China. Electronic address:

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http://dx.doi.org/10.1016/j.envint.2017.04.005DOI Listing
July 2017

Phytoavailability and mechanism of bound PAH residues in filed contaminated soils.

Environ Pollut 2017 Mar 4;222:465-476. Epub 2017 Jan 4.

Institute of Organic Contaminant Control and Soil Remediation, College of Resource and Environmental Sciences, Nanjing Agricultural University, Nanjing 210095, PR China.

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http://dx.doi.org/10.1016/j.envpol.2016.11.076DOI Listing
March 2017

A quantitative LC-MS/MS method for simultaneous determination of cocaine and its metabolites in whole blood.

J Pharm Biomed Anal 2017 Feb 11;134:243-251. Epub 2016 Nov 11.

Molecular Modeling and Biopharmaceutical Center, Department of Pharmaceutical Sciences, College of Pharmacy, University of Kentucky, 789 South Limestone Street, Lexington, KY 40536, United States. Electronic address:

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http://dx.doi.org/10.1016/j.jpba.2016.11.024DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5196007PMC
February 2017

Polycyclic aromatic hydrocarbons exposure decreased sperm mitochondrial DNA copy number: A cross-sectional study (MARHCS) in Chongqing, China.

Environ Pollut 2017 Jan 15;220(Pt A):680-687. Epub 2016 Oct 15.

Institute of Toxicology, College of Preventive Medicine, Third Military Medical University, Chongqing, China. Electronic address:

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http://dx.doi.org/10.1016/j.envpol.2016.10.026DOI Listing
January 2017

Reply to comment on "Effects of cell phone use on semen parameters: Results from the MARHCS cohort study in Chongqing, China".

Environ Int 2017 01 9;98:231-232. Epub 2016 Nov 9.

Institute of Toxicology, College of Preventive Medicine, Third Military Medical University, Chongqing, China. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S01604120163050
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http://dx.doi.org/10.1016/j.envint.2016.10.026DOI Listing
January 2017

Effects of a cocaine hydrolase engineered from human butyrylcholinesterase on metabolic profile of cocaine in rats.

Chem Biol Interact 2016 Nov 3;259(Pt B):104-109. Epub 2016 May 3.

Molecular Modeling and Biopharmaceutical Center, College of Pharmacy, University of Kentucky, 789 South Limestone Street, Lexington, KY 40536, United States; Department of Pharmaceutical Sciences, College of Pharmacy, University of Kentucky, 789 South Limestone Street, Lexington, KY 40536, United States. Electronic address:

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http://dx.doi.org/10.1016/j.cbi.2016.05.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5094907PMC
November 2016

Metabolic Enzymes of Cocaine Metabolite Benzoylecgonine.

ACS Chem Biol 2016 08 9;11(8):2186-94. Epub 2016 Jun 9.

Molecular Modeling and Biopharmaceutical Center and Department of Pharmaceutical Sciences, College of Pharmacy, University of Kentucky , 789 South Limestone Street, Lexington, Kentucky 40536, United States.

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http://dx.doi.org/10.1021/acschembio.6b00277DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5626564PMC
August 2016

Association between Genetic Polymorphisms of DNA Repair Genes and Chromosomal Damage for 1,3-Butadiene-Exposed Workers in a Matched Study in China.

Biomed Res Int 2015 3;2015:234675. Epub 2015 Aug 3.

Institute of Toxicology, College of Preventive Medicine, Third Military Medical University, Chongqing 400038, China.

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http://dx.doi.org/10.1155/2015/234675DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4538405PMC
May 2016

Effects of cell phone use on semen parameters: Results from the MARHCS cohort study in Chongqing, China.

Environ Int 2016 May 4;91:116-21. Epub 2016 Mar 4.

Institute of Toxicology, College of Preventive Medicine, Third Military Medical University, Chongqing, China. Electronic address:

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http://dx.doi.org/10.1016/j.envint.2016.02.028DOI Listing
May 2016

Anogenital distance is associated with serum reproductive hormones, but not with semen quality in young men.

Hum Reprod 2016 May 6;31(5):958-67. Epub 2016 Apr 6.

Key Lab of Medical Protection for Electromagnetic Radiation, Ministry of Education of China, Institute of Toxicology, College of Preventive Medicine, Third Military Medical University, Chongqing, PR China

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http://dx.doi.org/10.1093/humrep/dew052DOI Listing
May 2016

Lifestyles Associated With Human Semen Quality: Results From MARHCS Cohort Study in Chongqing, China.

Medicine (Baltimore) 2015 Jul;94(28):e1166

From the Institute of Toxicology (HuanY, QC, NZ, LS, LT, HC, GZ, LH, XW, PZ, KP, KL, TL, ZC, JL, LA, JC), College of Preventive Medicine, Third Military Medical University; The Key Laboratory of Birth Defects and Reproductive Health of National Health and Family Planning Commission (Chongqing Population and Family Planning Science and Technology Research Institute) (HB, LL, MM, HaoY); and Department of Environmental Hygiene (ZZ), College of Preventive Medicine, Third Military Medical University, Chongqing, P.R. China.

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http://dx.doi.org/10.1097/MD.0000000000001166DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4617091PMC
July 2015

Associations between variants on ADIPOQ and ADIPOR1 with colorectal cancer risk: a Chinese case-control study and updated meta-analysis.

BMC Med Genet 2014 Dec 17;15:137. Epub 2014 Dec 17.

Key Laboratory of Food Safety Research, Institute for Nutritional Sciences, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, University of Chinese Academy of Sciences, Shanghai, 200031, P. R China.

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http://dx.doi.org/10.1186/s12881-014-0137-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4411774PMC
December 2014

Air pollution and decreased semen quality: a comparative study of Chongqing urban and rural areas.

Environ Pollut 2014 Apr 1;187:145-52. Epub 2014 Feb 1.

Institute of Toxicology, College of Preventive Medicine, Third Military Medical University, Chongqing 400038, People's Republic of China. Electronic address:

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http://dx.doi.org/10.1016/j.envpol.2013.12.030DOI Listing
April 2014

Prevalence of cutaneous adverse drug reactions in Southwest China: an 11-year retrospective survey on in-patients of a dermatology ward.

Dermatitis 2012 Mar-Apr;23(2):81-5

Department of Dermatology, Southwest Hospital, The Third Military Medical University, Chongqing, China.

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http://dx.doi.org/10.1097/DER.0b013e31823d1aaeDOI Listing
April 2013

Socio-psycho-behavioural factors associated with male semen quality in China: results from 1346 healthy men in Chongqing.

J Fam Plann Reprod Health Care 2013 Apr 20;39(2):102-10. Epub 2012 Aug 20.

Third Military Medical University, Department of Social Medicine and Health Service Management, Chongqing, China.

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http://jfprhc.bmj.com/content/early/2012/08/19/jfprhc-2011-1
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http://jfprhc.bmj.com/lookup/doi/10.1136/jfprhc-2011-100276
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http://dx.doi.org/10.1136/jfprhc-2011-100276DOI Listing
April 2013

XRCC1 Arg280His polymorphism and glioma risk: A meta-analysis involving 1439 cases and 2564 controls.

Pak J Med Sci 2013 Jan;29(1):37-42

Weiqun Shu, Department of Environmental Hygiene, College of Preventive Medicine, Third Military Medical University, Chongqing, China.

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http://dx.doi.org/10.12669/pjms.291.2694DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3809186PMC
January 2013

The XRCC1 Arg194Trp polymorphism is not a risk factor for glioma: A meta-analysis involving 1,440 cases and 2,562 controls.

Exp Ther Med 2012 Dec 18;4(6):1057-1062. Epub 2012 Sep 18.

Department of Environmental Hygiene, College of Preventive Medicine, Third Military Medical University, Chongqing 400038;

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http://dx.doi.org/10.3892/etm.2012.716DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3494116PMC
December 2012

Genetic variants of a BH3-only pro-apoptotic gene, PUMA, and risk of HPV16-associated squamous cell carcinoma of the head and neck.

Mol Carcinog 2012 Oct 15;51 Suppl 1:E54-64. Epub 2011 Nov 15.

Department of Epidemiology, The University of Texas MD Anderson Cancer Center, Houston, Texas 77030, USA.

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http://dx.doi.org/10.1002/mc.21838DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3326219PMC
October 2012

Genetic variants of NOXA and MCL1 modify the risk of HPV16-associated squamous cell carcinoma of the head and neck.

BMC Cancer 2012 May 1;12:159. Epub 2012 May 1.

Department of Epidemiology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.

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http://dx.doi.org/10.1186/1471-2407-12-159DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3428689PMC
May 2012

Shortened telomere length is associated with increased risk of cancer: a meta-analysis.

PLoS One 2011 10;6(6):e20466. Epub 2011 Jun 10.

Department of Epidemiology, The University of Texas MD Anderson Cancer Center, Houston, Texas, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0020466PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3112149PMC
November 2011

Association between p21 Ser31Arg polymorphism and cancer risk: a meta-analysis.

Chin J Cancer 2011 Apr;30(4):254-63

Department of Epidemiology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4013352PMC
April 2011

The combined toxicity of dibutyl phthalate and benzo(a)pyrene on the reproductive system of male Sprague Dawley rats in vivo.

J Hazard Mater 2011 Feb 27;186(1):835-41. Epub 2010 Nov 27.

Laboratory of Reproductive Biology, Chongqing Medical University, Chongqing, PR China.

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http://dx.doi.org/10.1016/j.jhazmat.2010.11.078DOI Listing
February 2011

A novel polymorphism rs1329149 of CYP2E1 and a known polymorphism rs671 of ALDH2 of alcohol metabolizing enzymes are associated with colorectal cancer in a southwestern Chinese population.

Cancer Epidemiol Biomarkers Prev 2009 Sep 25;18(9):2522-7. Epub 2009 Aug 25.

Department of Hygienic Toxicology, College of Preventive Medicine, Third Military Medical University, Chongqing 400038, China.

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http://dx.doi.org/10.1158/1055-9965.EPI-09-0398DOI Listing
September 2009

Semen quality of 1346 healthy men, results from the Chongqing area of southwest China.

Hum Reprod 2009 Feb 1;24(2):459-69. Epub 2008 Dec 1.

Department of Epidemiology, College of Preventive Medicine, Third Military Medical University, Chongqing 400038, People's Republic of China.

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http://dx.doi.org/10.1093/humrep/den399DOI Listing
February 2009

HPRT mutations in lymphocytes from 1,3-butadiene-exposed workers in China.

Environ Health Perspect 2008 Feb;116(2):203-8

Department of Hygienic Toxicology, Preventive Medical College, Third Military Medical University, Chongqing, People's Republic of China.

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http://dx.doi.org/10.1289/ehp.10353DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2235214PMC
February 2008

Chromosomal aberrations, DNA strand breaks and gene mutations in nasopharyngeal cancer patients undergoing radiation therapy.

Mutat Res 2002 Jul;504(1-2):85-90

Hygiene Toxicology Department, Preventive Medicine College, Third Military Medical University, Chongqing, PR China.

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http://dx.doi.org/10.1016/s0027-5107(02)00082-9DOI Listing
July 2002