Ziying Yan

Ziying Yan

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Ziying Yan

Ziying Yan

Publications by authors named "Ziying Yan"

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Advances in gene therapy for cystic fibrosis lung disease.

Hum Mol Genet 2019 Oct;28(R1):R88-R94

Department of Anatomy and Cell Biology, Carver College of Medicine, University of Iowa, Iowa City, IA 52242, USA.

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http://dx.doi.org/10.1093/hmg/ddz139DOI Listing
October 2019

A Comprehensive RNA-seq Analysis of Human Bocavirus 1 Transcripts in Infected Human Airway Epithelium.

Viruses 2019 01 7;11(1). Epub 2019 Jan 7.

Department of Microbiology, Molecular Genetics and Immunology, University of Kansas Medical Center, Kansas City, KS 66160, USA.

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http://dx.doi.org/10.3390/v11010033DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6357044PMC
January 2019

Development of a Novel Recombinant Adeno-Associated Virus Production System Using Human Bocavirus 1 Helper Genes.

Mol Ther Methods Clin Dev 2018 Dec 4;11:40-51. Epub 2018 Oct 4.

Department of Microbiology, Molecular Genetics and Immunology, University of Kansas Medical Center, Kansas City, KS 66160, USA.

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http://dx.doi.org/10.1016/j.omtm.2018.09.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6205362PMC
December 2018

Human Parvovirus Infection of Human Airway Epithelia Induces Pyroptotic Cell Death by Inhibiting Apoptosis.

J Virol 2017 12 30;91(24). Epub 2017 Nov 30.

Department of Microbiology, Molecular Genetics and Immunology, University of Kansas Medical Center, Kansas City, Kansas, USA

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http://dx.doi.org/10.1128/JVI.01533-17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5709578PMC
December 2017

Human Bocavirus 1 Is a Novel Helper for Adeno-associated Virus Replication.

J Virol 2017 Sep 24;91(18). Epub 2017 Aug 24.

Department of Microbiology, Molecular Genetics and Immunology, University of Kansas Medical Center, Kansas City, Kansas, USA

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http://dx.doi.org/10.1128/JVI.00710-17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5571279PMC
September 2017

Parvovirus Expresses a Small Noncoding RNA That Plays an Essential Role in Virus Replication.

J Virol 2017 04 29;91(8). Epub 2017 Mar 29.

Department of Microbiology, Molecular Genetics and Immunology, University of Kansas Medical Center, Kansas City, Kansas, USA

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http://dx.doi.org/10.1128/JVI.02375-16DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5375684PMC
April 2017

DNA Damage Signaling Is Required for Replication of Human Bocavirus 1 DNA in Dividing HEK293 Cells.

J Virol 2017 Jan 16;91(1). Epub 2016 Dec 16.

Department of Microbiology, Molecular Genetics and Immunology, University of Kansas Medical Center, Kansas City, Kansas, USA

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http://dx.doi.org/10.1128/JVI.01831-16DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5165215PMC
January 2017

Analysis of cis and trans Requirements for DNA Replication at the Right-End Hairpin of the Human Bocavirus 1 Genome.

J Virol 2016 09 12;90(17):7761-77. Epub 2016 Aug 12.

Department of Microbiology, Molecular Genetics and Immunology, University of Kansas Medical Center, Kansas City, Kansas, USA

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http://jvi.asm.org/content/90/17/7761.full.pdf
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http://jvi.asm.org/lookup/doi/10.1128/JVI.00708-16
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http://dx.doi.org/10.1128/JVI.00708-16DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4988151PMC
September 2016

Nonstructural Protein NP1 of Human Bocavirus 1 Plays a Critical Role in the Expression of Viral Capsid Proteins.

J Virol 2016 May 14;90(9):4658-4669. Epub 2016 Apr 14.

Department of Microbiology, Molecular Genetics and Immunology, University of Kansas Medical Center, Kansas City, Kansas, USA

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http://dx.doi.org/10.1128/JVI.02964-15DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4836317PMC
May 2016

Definitive localization of intracellular proteins: Novel approach using CRISPR-Cas9 genome editing, with glucose 6-phosphate dehydrogenase as a model.

Anal Biochem 2016 Feb 11;494:55-67. Epub 2015 Nov 11.

Joslin Diabetes Center, 1 Joslin Place, Boston, MA, 02215, USA; Harvard Medical School, 25 Shattuck St., Boston, MA, 02115, USA; Beth Israel Deaconess Medical Center, 330 Brookline Ave., Boston, MA, 02215, USA.

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http://dx.doi.org/10.1016/j.ab.2015.11.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4695245PMC
February 2016

Replication of an Autonomous Human Parvovirus in Non-dividing Human Airway Epithelium Is Facilitated through the DNA Damage and Repair Pathways.

PLoS Pathog 2016 Jan 14;12(1):e1005399. Epub 2016 Jan 14.

Department of Microbiology, Molecular Genetics and Immunology, University of Kansas Medical Center, Kansas City, Kansas, United States of America.

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http://dx.doi.org/10.1371/journal.ppat.1005399DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4713420PMC
January 2016

Identification and Functional Analysis of Novel Nonstructural Proteins of Human Bocavirus 1.

J Virol 2015 Oct 29;89(19):10097-109. Epub 2015 Jul 29.

Department of Microbiology, Molecular Genetics and Immunology, University of Kansas Medical Center, Kansas City, Kansas, USA

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http://dx.doi.org/10.1128/JVI.01374-15DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4577888PMC
October 2015

Optimization of Recombinant Adeno-Associated Virus-Mediated Expression for Large Transgenes, Using a Synthetic Promoter and Tandem Array Enhancers.

Hum Gene Ther 2015 Jun 20;26(6):334-46. Epub 2015 Apr 20.

1 Department of Anatomy and Cell Biology, University of Iowa School of Medicine , Iowa City, IA 52242.

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http://dx.doi.org/10.1089/hum.2015.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4492606PMC
June 2015

Ferret and pig models of cystic fibrosis: prospects and promise for gene therapy.

Hum Gene Ther Clin Dev 2015 Mar 12;26(1):38-49. Epub 2015 Feb 12.

1 Department of Anatomy and Cell Biology, University of Iowa School of Medicine , Iowa City, IA 52242.

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http://dx.doi.org/10.1089/humc.2014.154DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4367511PMC
March 2015

Establishment of a reverse genetics system for studying human bocavirus in human airway epithelia.

PLoS Pathog 2012 30;8(8):e1002899. Epub 2012 Aug 30.

Department of Microbiology, Molecular Genetics and Immunology, University of Kansas Medical Center, Kansas City, Kansas, USA.

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http://dx.doi.org/10.1371/journal.ppat.1002899DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3431310PMC
September 2014

Hepatocytes produce TNF-α following hypoxia-reoxygenation and liver ischemia-reperfusion in a NADPH oxidase- and c-Src-dependent manner.

Am J Physiol Gastrointest Liver Physiol 2013 Jul 2;305(1):G84-94. Epub 2013 May 2.

Department of Anatomy and Cell Biology, The University of Iowa, Iowa City, IA 52242, USA.

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http://dx.doi.org/10.1152/ajpgi.00430.2012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3725690PMC
July 2013

In vitro modeling of human bocavirus 1 infection of polarized primary human airway epithelia.

J Virol 2013 Apr 23;87(7):4097-102. Epub 2013 Jan 23.

College of Life Sciences, Central China Normal University, Wuhan, China.

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http://dx.doi.org/10.1128/JVI.03132-12DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3624236PMC
April 2013

Abnormal endocrine pancreas function at birth in cystic fibrosis ferrets.

J Clin Invest 2012 Oct 17;122(10):3755-68. Epub 2012 Sep 17.

Department of Pathology, College of Public Health, and Fraternal Order of Eagles Diabetes Research Center, University of Iowa, Iowa City, Iowa 52242, USA.

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http://dx.doi.org/10.1172/JCI60610DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3534166PMC
October 2012

Directing integrin-linked endocytosis of recombinant AAV enhances productive FAK-dependent transduction.

Mol Ther 2012 May 10;20(5):972-83. Epub 2012 Jan 10.

Department of Anatomy and Cell Biology, College of Medicine, The University of Iowa, Iowa City, Iowa 52242, USA.

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http://linkinghub.elsevier.com/retrieve/pii/S152500161631937
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http://dx.doi.org/10.1038/mt.2011.295DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3345987PMC
May 2012

Unique characteristics of AAV1, 2, and 5 viral entry, intracellular trafficking, and nuclear import define transduction efficiency in HeLa cells.

Hum Gene Ther 2011 Nov 28;22(11):1433-44. Epub 2011 Jun 28.

Department of Anatomy and Cell Biology, University of Iowa Carver College of Medicine, Iowa City, IA 52242, USA.

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http://dx.doi.org/10.1089/hum.2011.044DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3225038PMC
November 2011

Control of hepatic nuclear superoxide production by glucose 6-phosphate dehydrogenase and NADPH oxidase-4.

J Biol Chem 2011 Mar 6;286(11):8977-87. Epub 2011 Jan 6.

Department of Anatomy and Cell Biology, College of Medicine, The University of Iowa, Iowa City, Iowa 52242, USA.

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http://dx.doi.org/10.1074/jbc.M110.193821DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3059029PMC
March 2011

Dual reporter comparative indexing of rAAV pseudotyped vectors in chimpanzee airway.

Mol Ther 2010 Mar 13;18(3):594-600. Epub 2009 Oct 13.

Department of Pediatrics, University of Massachusetts Medical School, Worcester, Massachusetts 01655, USA.

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http://dx.doi.org/10.1038/mt.2009.230DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2839428PMC
March 2010

Analysis of adeno-associated virus progenitor cell transduction in mouse lung.

Mol Ther 2009 Feb 25;17(2):285-93. Epub 2008 Nov 25.

Department of Anatomy and Cell Biology, College of Medicine, The University of Iowa, Iowa City, Iowa, USA.

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http://dx.doi.org/10.1038/mt.2008.248DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2665184PMC
February 2009

Indexing TNF-alpha gene expression using a gene-targeted reporter cell line.

BMC Biol 2009 Feb 16;7. Epub 2009 Feb 16.

Department of Anatomy and Cell Biology, Carver College of Medicine, University of Iowa, Iowa City, IA, USA.

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http://dx.doi.org/10.1186/1741-7007-7-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2657777PMC
February 2009

Adeno-associated virus-targeted disruption of the CFTR gene in cloned ferrets.

J Clin Invest 2008 Apr;118(4):1578-83

Department of Anatomy and Cell Biology, University of Iowa Carver College of Medicine, Iowa City, Iowa 52242, USA.

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http://dx.doi.org/10.1172/JCI34599DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2263147PMC
April 2008

Bioelectric properties of chloride channels in human, pig, ferret, and mouse airway epithelia.

Am J Respir Cell Mol Biol 2007 Mar 28;36(3):313-23. Epub 2006 Sep 28.

Department of Anatomy, The Center for Gene Therapy, College of Medicine, The University of Iowa, Iowa City, Iowa 52242, USA.

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http://dx.doi.org/10.1165/rcmb.2006-0286OCDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1894945PMC
March 2007

Unique biologic properties of recombinant AAV1 transduction in polarized human airway epithelia.

J Biol Chem 2006 Oct 9;281(40):29684-92. Epub 2006 Aug 9.

Department of Anatomy and Cell Biology, University of Iowa College of Medicine, Iowa City, Iowa 52242, USA.

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http://dx.doi.org/10.1074/jbc.M604099200DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1712671PMC
October 2006

Species-specific differences in mouse and human airway epithelial biology of recombinant adeno-associated virus transduction.

Am J Respir Cell Mol Biol 2006 Jan 29;34(1):56-64. Epub 2005 Sep 29.

Department of Anatomy and Cell Biology, University of Iowa College of Medicine, 51 Newton Road, Iowa City, IA 52242, USA.

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http://www.atsjournals.org/doi/abs/10.1165/rcmb.2005-0189OC
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http://dx.doi.org/10.1165/rcmb.2005-0189OCDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1752084PMC
January 2006

Inverted terminal repeat sequences are important for intermolecular recombination and circularization of adeno-associated virus genomes.

J Virol 2005 Jan;79(1):364-79

Department of Anatomy and Cell Biology, University of Iowa School of Medicine, Iowa City, Iowa 52242-1109, USA.

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http://dx.doi.org/10.1128/JVI.79.1.364-379.2005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC538689PMC
January 2005

Targeted correction of single-base-pair mutations with adeno-associated virus vectors under nonselective conditions.

J Virol 2004 Apr;78(8):4165-75

Department of Anatomy and Cell Biology and the Center for Gene Therapy of Cystic Fibrosis and Other Genetic Diseases, University of Iowa College of Medicine, Iowa City, Iowa 52242, USA.

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http://jvi.asm.org/content/78/8/4165.full.pdf
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC374254PMC
http://dx.doi.org/10.1128/jvi.78.8.4165-4175.2004DOI Listing
April 2004

Second-strand genome conversion of adeno-associated virus type 2 (AAV-2) and AAV-5 is not rate limiting following apical infection of polarized human airway epithelia.

J Virol 2003 Jul;77(13):7361-6

Department of Anatomy and Cell Biology, Gene Therapy Center for Cystic Fibrosis and Other Genetic Diseases, University of Iowa, Iowa City, Iowa 52242, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC164830PMC
http://dx.doi.org/10.1128/jvi.77.13.7361-7366.2003DOI Listing
July 2003

Trans-splicing vectors expand the packaging limits of adeno-associated virus for gene therapy applications.

Methods Mol Med 2003 ;76:287-307

Department of Molecular Microbiology and Immunology, School of Medicine, University of Missouri, Columbia, MO, USA.

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April 2003

Efficiency of chimeraplast gene targeting by direct nuclear injection using a GFP recovery assay.

Mol Ther 2003 Feb;7(2):248-53

Department of Anatomy and Cell Biology and the Center for Gene Therapy of Cystic Fibrosis and Other Genetic Diseases, University of Iowa College of Medicine, Iowa City, IA 52242-1109, USA.

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http://dx.doi.org/10.1016/s1525-0016(02)00039-4DOI Listing
February 2003

Recombinant AAV-mediated gene delivery using dual vector heterodimerization.

Methods Enzymol 2002 ;346:334-57

Department of Anatomy and Cell Biology, University of Iowa College of Medicine, Iowa City, Iowa 52242, USA.

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http://dx.doi.org/10.1016/s0076-6879(02)46065-xDOI Listing
April 2002

Ubiquitination of both adeno-associated virus type 2 and 5 capsid proteins affects the transduction efficiency of recombinant vectors.

J Virol 2002 Mar;76(5):2043-53

Department of Anatomy and Cell Biology, University of Iowa College of Medicine, 51 Newton Road, Iowa City, IA 52242, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC135943PMC
http://dx.doi.org/10.1128/jvi.76.5.2043-2053.2002DOI Listing
March 2002