Publications

Redox active metals and H2O2 mediate the increased efficacy of pharmacological ascorbate in combination with gemcitabine or radiation in pre-clinical sarcoma models.
Redox Biol 2017 Sep 28;14:417-422. Epub 2017 Sep 28.
Free Radical and Radiation Biology Program, Department of Radiation Oncology, Holden Comprehensive Cancer Center, The University of Iowa, Iowa City, IA 52242, United States. Electronic address:


Pharmacological Ascorbate Radiosensitizes Pancreatic Cancer.
Cancer Res 2015 Aug 16;75(16):3314-26. Epub 2015 Jun 16.
Department of Surgery, University of Iowa College of Medicine, Iowa City, Iowa. Department of Radiation Oncology, University of Iowa College of Medicine, Iowa City, Iowa. Holden Comprehensive Cancer Center, Iowa City, Iowa. Veterans Affairs Medical Center, Iowa City, Iowa.

Ketogenic diets as an adjuvant cancer therapy: History and potential mechanism.
Redox Biol 2014 7;2:963-70. Epub 2014 Aug 7.
Free Radical and Radiation Biology Program, Department of Radiation Oncology, Holden Comprehensive Cancer Center, University of Iowa, Iowa City, IA 52242, USA.

Extracellular superoxide dismutase suppresses hypoxia-inducible factor-1α in pancreatic cancer.
Free Radic Biol Med 2014 Apr 7;69:357-66. Epub 2014 Feb 7.
Department of Surgery, The University of Iowa College of Medicine, Iowa City, IA 52242, USA; Department of Radiation Oncology, The University of Iowa College of Medicine, Iowa City, IA 52242, USA; Holden Comprehensive Cancer Center, Iowa City, IA 52242, USA; Veterans Affairs Medical Center, Iowa City, IA 52242, USA. Electronic address:

Erlotinib-mediated inhibition of EGFR signaling induces metabolic oxidative stress through NOX4.
Cancer Res 2011 Jun 11;71(11):3932-40. Epub 2011 Apr 11.
Free Radical and Radiation Biology Program, Department of Radiation Oncology, Holden Comprehensive Cancer Center, The University of Iowa, Iowa City, Iowa 52242, USA.


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