Zilong Wen

Zilong Wen

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Zilong Wen

Publications by authors named "Zilong Wen"

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Optimal dilation time for combined small endoscopic sphincterotomy and balloon dilation for common bile duct stones: a multicentre, single-blinded, randomised controlled trial.

Lancet Gastroenterol Hepatol 2019 Jun 16;4(6):425-434. Epub 2019 Apr 16.

Fifth Department of General Surgery, The First Hospital of Lanzhou University, Lanzhou, China; Hepatopancreatobiliary Surgery Institute of Gansu Province, Clinical Medical College Cancer Center of Lanzhou University, Lanzhou, China; Key Laboratory of Biological Therapy and Regenerative Medicine Transformation Gansu Province, Lanzhou, China. Electronic address:

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http://dx.doi.org/10.1016/S2468-1253(19)30075-5DOI Listing
June 2019

Nlrc3-like is required for microglia maintenance in zebrafish.

J Genet Genomics 2019 Jun 22. Epub 2019 Jun 22.

Division of Life Science and State Key Laboratory of Molecular Neuroscience, Center of Systems Biology and Human Health, The Hong Kong University of Science and Technology, Clearwater Bay, Kowloon, Hong Kong, China. Electronic address:

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http://dx.doi.org/10.1016/j.jgg.2019.06.002DOI Listing
June 2019

An Ectoderm-Derived Myeloid-like Cell Population Functions as Antigen Transporters for Langerhans Cells in Zebrafish Epidermis.

Dev Cell 2019 May 18;49(4):605-617.e5. Epub 2019 Apr 18.

Division of Life Science, State Key Laboratory of Molecular Neuroscience and Center of Systems Biology and Human Health, Hong Kong University of Science and Technology, Clear Water Bay, Kowloon, Hong Kong, P.R. China; Shenzhen Key Laboratory for Neuronal Structural Biology, Biomedical Research Institute, Shenzhen Peking University-Hong Kong University of Science and Technology Medical Center, Shenzhen 518036, P.R. China. Electronic address:

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http://dx.doi.org/10.1016/j.devcel.2019.03.028DOI Listing
May 2019

Dysregulation of Microglial Function Contributes to Neuronal Impairment in Mcoln1a-Deficient Zebrafish.

iScience 2019 Mar 2;13:391-401. Epub 2019 Mar 2.

Division of Life Science, State Key Laboratory of Molecular Neuroscience and Center of Systems Biology and Human Health, the Hong Kong University of Science and Technology, Clear Water Bay, Kowloon, Hong Kong, PR. China; Shenzhen Key Laboratory for Neuronal Structural Biology, Biomedical Research Institute, Shenzhen Peking University-Hong Kong University of Science and Technology Medical Center, Shenzhen 518036, PR. China. Electronic address:

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http://dx.doi.org/10.1016/j.isci.2019.02.031DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6426713PMC
March 2019

Il34-Csf1r Pathway Regulates the Migration and Colonization of Microglial Precursors.

Dev Cell 2018 09;46(5):552-563.e4

Division of Life Science, State Key Laboratory of Molecular Neuroscience, Hong Kong University of Science and Technology, Clear Water Bay, Kowloon, Hong Kong, PRC; Center of Systems Biology and Human Health, Hong Kong University of Science and Technology, Clear Water Bay, Kowloon, Hong Kong, PRC; Shenzhen Key Laboratory for Neuronal Structural Biology, Biomedical Research Institute, Shenzhen Peking University-Hong Kong University of Science and Technology Medical Center, Shenzhen, Guangdong 518036, PRC. Electronic address:

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http://dx.doi.org/10.1016/j.devcel.2018.08.005DOI Listing
September 2018

Adult zebrafish Langerhans cells arise from hematopoietic stem/progenitor cells.

Elife 2018 06 15;7. Epub 2018 Jun 15.

Division of Cell, Developmental and Integrative Biology, School of Medicine, South China University of Technology, Guangzhou, China.

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http://dx.doi.org/10.7554/eLife.36131DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6017808PMC
June 2018

The first wave of T lymphopoiesis in zebrafish arises from aorta endothelium independent of hematopoietic stem cells.

J Exp Med 2017 Nov 20;214(11):3347-3360. Epub 2017 Sep 20.

Division of Life Science, State Key Laboratory of Molecular Neuroscience and Center of Systems Biology and Human Health, Hong Kong University of Science and Technology, Clear Water Bay, Kowloon, Hong Kong, P.R. China

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http://dx.doi.org/10.1084/jem.20170488DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5679161PMC
November 2017

Role of AP-2α and MAPK7 in the regulation of autocrine TGF-β/miR-200b signals to maintain epithelial-mesenchymal transition in cholangiocarcinoma.

J Hematol Oncol 2017 10 30;10(1):170. Epub 2017 Oct 30.

Department of Hepatobiliary Surgery, The Second Affiliated Hospital of Guangzhou Medical University, No 250 East Changgang Road, Guangzhou, 510260, China.

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http://dx.doi.org/10.1186/s13045-017-0528-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5663068PMC
October 2017

Distinct regulatory networks control the development of macrophages of different origins in zebrafish.

Blood 2017 01 9;129(4):509-519. Epub 2016 Dec 9.

Division of Life Science, State Key Laboratory of Molecular Neuroscience and Center of Systems Biology and Human Health, Hong Kong University of Science and Technology, Clear Water Bay, Kowloon, Hong Kong, People's Republic of China.

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http://dx.doi.org/10.1182/blood-2016-07-727651DOI Listing
January 2017

Cebpα is essential for the embryonic myeloid progenitor and neutrophil maintenance in zebrafish.

J Genet Genomics 2016 10 3;43(10):593-600. Epub 2016 Sep 3.

Key Laboratory of Zebrafish Modeling and Drug Screening for Human Diseases of Guangdong Higher Education Institutes, Department of Cell Biology, School of Basic Medical Sciences, Southern Medical University, Guangzhou 510515, China. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S16738527163012
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http://dx.doi.org/10.1016/j.jgg.2016.09.001DOI Listing
October 2016

c-Myb acts in parallel and cooperatively with Cebp1 to regulate neutrophil maturation in zebrafish.

Blood 2016 07 6;128(3):415-26. Epub 2016 Jun 6.

Key Laboratory of Zebrafish Modeling and Drug Screening for Human Diseases of Guangdong Higher Education Institutes, Department of Developmental Biology, School of Basic Medical Sciences, Southern Medical University, Guangzhou, People's Republic of China; and.

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http://dx.doi.org/10.1182/blood-2015-12-686147DOI Listing
July 2016

Microglia Colonization of Developing Zebrafish Midbrain Is Promoted by Apoptotic Neuron and Lysophosphatidylcholine.

Dev Cell 2016 07 14;38(2):214-22. Epub 2016 Jul 14.

Division of Life Science, State Key Laboratory of Molecular Neuroscience and Center of Systems Biology and Human Health, Hong Kong University of Science and Technology, Clear Water Bay, Kowloon, Hong Kong, P.R. China. Electronic address:

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http://www.cell.com/developmental-cell/pdf/S1534-5807(16)304
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http://www.cell.com/cms/attachment/2062037557/2063490178/mmc
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http://linkinghub.elsevier.com/retrieve/pii/S153458071630421
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http://dx.doi.org/10.1016/j.devcel.2016.06.018DOI Listing
July 2016

RNA polymerase III component Rpc9 regulates hematopoietic stem and progenitor cell maintenance in zebrafish.

Development 2016 06 5;143(12):2103-10. Epub 2016 May 5.

State Key Laboratory of Membrane Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing 100101, China University of Chinese Academy of Sciences, Beijing 100049, China

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http://dev.biologists.org/content/develop/143/12/2103.full.p
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http://dev.biologists.org/content/develop/early/2016/05/04/d
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http://dx.doi.org/10.1242/dev.126797DOI Listing
June 2016

Temporal-Spatial Resolution Fate Mapping Reveals Distinct Origins for Embryonic and Adult Microglia in Zebrafish.

Dev Cell 2015 Sep;34(6):632-41

Division of Life Science, State Key Laboratory of Molecular Neuroscience, Center of Systems Biology and Human Health, Hong Kong University of Science and Technology, Clear Water Bay, Kowloon, Hong Kong, PRC. Electronic address:

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http://dx.doi.org/10.1016/j.devcel.2015.08.018DOI Listing
September 2015

Functions of idh1 and its mutation in the regulation of developmental hematopoiesis in zebrafish.

Blood 2015 May 16;125(19):2974-84. Epub 2015 Mar 16.

Division of Haematology, Department of Medicine, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong, China;

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http://dx.doi.org/10.1182/blood-2014-09-601187DOI Listing
May 2015

Sumoylation of CCAAT/enhancer-binding protein α is implicated in hematopoietic stem/progenitor cell development through regulating runx1 in zebrafish.

Sci Rep 2015 Mar 11;5:9011. Epub 2015 Mar 11.

1] CNRS-LIA124, Sino-French Research Center for Life Sciences and Genomics, State Key Laboratory of Medical Genomics, Rui-Jin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China [2] Université de Paris 7/INSERM/CNRS UMR 944/7212, Equipe Labellisée No. 11 Ligue Nationale Contre le Cancer, Hôpital St. Louis, Paris, France.

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http://dx.doi.org/10.1038/srep09011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4355724PMC
March 2015

In Vivo nonlinear optical imaging of immune responses: tissue injury and infection.

Biophys J 2014 Nov;107(10):2436-43

Biophotonics Research Laboratory, Department of Electronic and Computer Engineering, Hong Kong University of Science and Technology, Clear Water Bay, Kowloon, Hong Kong SAR, P.R. China; Center of Systems Biology and Human Health, School of Science and Institute for Advanced Study, Hong Kong University of Science and Technology, Clear Water Bay, Kowloon, Hong Kong SAR, P.R. China. Electronic address:

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http://dx.doi.org/10.1016/j.bpj.2014.09.041DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4241436PMC
November 2014

IL-1β and reactive oxygen species differentially regulate neutrophil directional migration and Basal random motility in a zebrafish injury-induced inflammation model.

J Immunol 2014 Jun 16;192(12):5998-6008. Epub 2014 May 16.

State Key Laboratory of Molecular Neuroscience, Center of Systems Biology and Human Health, Division of Life Science, Hong Kong University of Science and Technology, Kowloon, Hong Kong, China;

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http://dx.doi.org/10.4049/jimmunol.1301645DOI Listing
June 2014

In vivo micro-vascular imaging and flow cytometry in zebrafish using two-photon excited endogenous fluorescence.

Biomed Opt Express 2014 Mar 4;5(3):653-63. Epub 2014 Feb 4.

Biophotonics Research Laboratory, Department of Electronic and Computer Engineering, Hong Kong University of Science and Technology, Clear Water Bay, Kowloon, Hong Kong SAR, China ; Center of Systems Biology and Human Health, School of Science and Institute for Advanced Study, Hong Kong University of Science and Technology, Clear Water Bay, Kowloon, Hong Kong SAR, China.

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http://www.ece.ust.hk/~eequ/Dr%20Qu's%20Homepage_files/2014_
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https://www.osapublishing.org/abstract.cfm?URI=boe-5-3-653
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http://dx.doi.org/10.1364/BOE.5.000653DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3959833PMC
March 2014

Hemogenic endothelium specification and hematopoietic stem cell maintenance employ distinct Scl isoforms.

Development 2013 Oct;140(19):3977-85

State Key Laboratory of Molecular Neuroscience, Center of Systems Biology and Human Health, Division of Life Science, Hong Kong University of Science and Technology, Clear Water Bay, Kowloon, Hong Kong, P.R. China.

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http://dx.doi.org/10.1242/dev.097071DOI Listing
October 2013

Label-free in vivo imaging of human leukocytes using two-photon excited endogenous fluorescence.

J Biomed Opt 2013 Apr;18(4):040504

Hong Kong University of Science and Technology, Department of Electronic and Computer Engineering, Biophotonics Research Laboratory, Clear Water Bay, Kowloon, Hong Kong SAR, China.

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http://dx.doi.org/10.1117/1.JBO.18.4.040504DOI Listing
April 2013

SUMO1-activating enzyme subunit 1 is essential for the survival of hematopoietic stem/progenitor cells in zebrafish.

Development 2012 Dec;139(23):4321-9

State Key Laboratory of Molecular Neuroscience, Center of Systems Biology and Human Health, Division of Life Science, The Hong Kong University of Science and Technology, Clear Water Bay, Kowloon, Hong Kong, P. R. China.

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http://dx.doi.org/10.1242/dev.081869DOI Listing
December 2012

Antiparallel coiled-coil-mediated dimerization of myosin X.

Proc Natl Acad Sci U S A 2012 Oct 10;109(43):17388-93. Epub 2012 Sep 10.

Division of Life Science, State Key Laboratory of Molecular Neuroscience and Center of Systems Biology and Human Health, School of Science and Institute for Advanced Study, Hong Kong University of Science and Technology, Kowloon, Hong Kong, China.

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http://dx.doi.org/10.1073/pnas.1208642109DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3491486PMC
October 2012

Myelopoiesis during zebrafish early development.

J Genet Genomics 2012 Sep 4;39(9):435-42. Epub 2012 Aug 4.

State Key Laboratory of Molecular Neuroscience, Division of Life Science, Hong Kong University of Science and Technology, Clear Water Bay, Kowloon, Hong Kong, China.

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http://dx.doi.org/10.1016/j.jgg.2012.06.005DOI Listing
September 2012

Label-free in vivo flow cytometry in zebrafish using two-photon autofluorescence imaging.

Opt Lett 2012 Jul;37(13):2490-2

Department of Electronic and Computer Engineering, Hong Kong University of Science and Technology, Clear Water Bay, Kowloon, Hong Kong, China.

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http://dx.doi.org/10.1364/OL.37.002490DOI Listing
July 2012

Runx1 regulates embryonic myeloid fate choice in zebrafish through a negative feedback loop inhibiting Pu.1 expression.

Blood 2012 May 4;119(22):5239-49. Epub 2012 Apr 4.

State Key Laboratory of Molecular Neuroscience, Division of Life Science, Hong Kong University of Science and Technology, Hong Kong, PR China.

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http://dx.doi.org/10.1182/blood-2011-12-398362DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3369614PMC
May 2012

cMyb regulates hematopoietic stem/progenitor cell mobilization during zebrafish hematopoiesis.

Blood 2011 Oct 19;118(15):4093-101. Epub 2011 Aug 19.

State Key Laboratory of Molecular Neuroscience, Division of Life Science, The Hong Kong University of Science and Technology, Hong Kong, People's Republic of China.

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http://www.bloodjournal.org/cgi/doi/10.1182/blood-2011-03-34
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http://dx.doi.org/10.1182/blood-2011-03-342501DOI Listing
October 2011

Rumba and Haus3 are essential factors for the maintenance of hematopoietic stem/progenitor cells during zebrafish hematopoiesis.

Development 2011 Feb 12;138(4):619-29. Epub 2011 Jan 12.

State Key Laboratory of Molecular Neuroscience, Department of Biochemistry, Hong Kong University of Science and Technology, Clear Water Bay, Kowloon, Hong Kong, PR China.

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http://dx.doi.org/10.1242/dev.054536DOI Listing
February 2011

Irf8 regulates macrophage versus neutrophil fate during zebrafish primitive myelopoiesis.

Blood 2011 Jan 15;117(4):1359-69. Epub 2010 Nov 15.

State Key Laboratory of Molecular Neuroscience, Department of Biochemistry, Hong Kong University of Science and Technology, Clear Water Bay, Kowloon, Hong Kong, People's Republic of China.

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http://dx.doi.org/10.1182/blood-2010-06-290700DOI Listing
January 2011

A Runx1 intronic enhancer marks hemogenic endothelial cells and hematopoietic stem cells.

Stem Cells 2010 Oct;28(10):1869-81

Cancer Science Institute of Singapore, National University of Singapore, Singapore.

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http://dx.doi.org/10.1002/stem.507DOI Listing
October 2010

Regulation of gene expression by FSP27 in white and brown adipose tissue.

BMC Genomics 2010 Jul 22;11:446. Epub 2010 Jul 22.

College of Life Sciences, Beijing Normal University Xinjiekouwai Street 19, Xichen District Beijing 100875, China.

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http://dx.doi.org/10.1186/1471-2164-11-446DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3091643PMC
July 2010

Autoinhibition of UNC5b revealed by the cytoplasmic domain structure of the receptor.

Mol Cell 2009 Mar;33(6):692-703

Department of Biochemistry, Molecular Neuroscience Center, Hong Kong University of Science and Technology, Clear Water Bay, Kowloon, Hong Kong.

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http://dx.doi.org/10.1016/j.molcel.2009.02.016DOI Listing
March 2009

Definitive hematopoietic stem/progenitor cells manifest distinct differentiation output in the zebrafish VDA and PBI.

Development 2009 Feb;136(4):647-54

Department of Biochemistry, the Hong Kong University of Science and Technology, Clear Water Bay, Kowloon, People's Republic of China.

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http://dx.doi.org/10.1242/dev.029637DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2646468PMC
February 2009

Cideb regulates diet-induced obesity, liver steatosis, and insulin sensitivity by controlling lipogenesis and fatty acid oxidation.

Diabetes 2007 Oct 23;56(10):2523-32. Epub 2007 Jul 23.

Department of Biology, Hong Kong University of Science and Technology, Clear Water Bay, Kowloon, Hong Kong.

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http://dx.doi.org/10.2337/db07-0040DOI Listing
October 2007

The zebrafish udu gene encodes a novel nuclear factor and is essential for primitive erythroid cell development.

Blood 2007 Jul 16;110(1):99-106. Epub 2007 Mar 16.

Laboratory of Molecular & Developmental Immunology, Institute of Molecular and Cell Biology, Proteos, Singapore.

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http://dx.doi.org/10.1182/blood-2006-11-059204DOI Listing
July 2007

Migratory path of definitive hematopoietic stem/progenitor cells during zebrafish development.

Blood 2007 Jun 27;109(12):5208-14. Epub 2007 Feb 27.

Laboratory of Molecular & Developmental Immunology, Institute of Molecular and Cell Biology, Proteos, Department of Biological Sciences, the National University of Singapore, Singapore.

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http://dx.doi.org/10.1182/blood-2007-01-069005DOI Listing
June 2007

Distinct functions for different scl isoforms in zebrafish primitive and definitive hematopoiesis.

PLoS Biol 2007 May;5(5):e132

Laboratory of Molecular and Developmental Immunology, Institute of Molecular and Cell Biology, Singapore, Singapore.

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http://dx.doi.org/10.1371/journal.pbio.0050132DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1858710PMC
May 2007

Amotl2 is essential for cell movements in zebrafish embryo and regulates c-Src translocation.

Development 2007 Mar;134(5):979-88

State Key Laboratory of Biomembrane and Membrane Biotechnology, Department of Biological Sciences and Biotechnology, Tsinghua University, Beijing 100084, China.

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http://dev.biologists.org/cgi/doi/10.1242/dev.02782
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http://dx.doi.org/10.1242/dev.02782DOI Listing
March 2007

The 5' zebrafish scl promoter targets transcription to the brain, spinal cord, and hematopoietic and endothelial progenitors.

Dev Dyn 2006 Jan;235(1):60-7

Laboratory of Molecular and Developmental Immunology, Institute of Molecular and Cell Biology, Proteos, Singapore.

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http://dx.doi.org/10.1002/dvdy.20613DOI Listing
January 2006

Loss of function of def selectively up-regulates Delta113p53 expression to arrest expansion growth of digestive organs in zebrafish.

Genes Dev 2005 Dec;19(23):2900-11

Laboratory of Functional Genomics, Laboratory of Molecular and Developmental Immunology, Laboratory of Control of p53 Pathway, Institute of Molecular and Cell Biology, Proteos, Singapore 138673.

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http://www.genesdev.org/cgi/doi/10.1101/gad.1366405
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http://dx.doi.org/10.1101/gad.1366405DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1315396PMC
December 2005

Identification of the conserved serine/threonine residues important for gibberellin-sensitivity of Arabidopsis RGL2 protein.

Plant J 2005 Oct;44(1):88-99

Institute of Molecular and Cell Biology, 61 Biopolis Drive, Proteos, Singapore 138673.

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http://dx.doi.org/10.1111/j.1365-313X.2005.02512.xDOI Listing
October 2005

Microarray analysis of zebrafish cloche mutant using amplified cDNA and identification of potential downstream target genes.

Dev Dyn 2005 Jul;233(3):1163-72

Laboratory of Molecular and Developmental Immunology, Institute of Molecular and Cell Biology, Proteos, Singapore.

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http://doi.wiley.com/10.1002/dvdy.20444
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http://dx.doi.org/10.1002/dvdy.20444DOI Listing
July 2005

Genome-wide identification of female-enriched genes in zebrafish.

Dev Dyn 2005 Jan;232(1):171-9

Institute of Molecular & Cell Biology, Proteos, Singapore.

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http://dx.doi.org/10.1002/dvdy.20210DOI Listing
January 2005

Chromatin-remodelling factor BRG1 selectively activates a subset of interferon-alpha-inducible genes.

Nat Cell Biol 2002 Oct;4(10):774-81

Laboratory of Molecular and Developmental Immunology, Institute of Molecular and Cell Biology, 30 Medical Drive, Singapore 117609.

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http://dx.doi.org/10.1038/ncb855DOI Listing
October 2002

Cloning and expression pattern of the lysozyme C gene in zebrafish.

Authors:
Feng Liu Zilong Wen

Mech Dev 2002 Apr;113(1):69-72

Laboratory of Molecular Immunology, Institute of Molecular Agrobiology, 1 Research Link, 117604, Singapore.

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April 2002